Zobrazeno 1 - 10
of 7 575
pro vyhledávání: '"muc1"'
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 11, Pp 1370-1382 (2024)
Objective·To identify the functional motifs of mucin 1 (MUC1) involved in regulating tumor cell proliferation, migration, and stemness maintenance.Methods·Mutational characteristics of the MUC1 gene across different cancers were identified from The
Externí odkaz:
https://doaj.org/article/18870c6f69344488a938d05d036fa083
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract MUC1 is a highly glycosylated transmembrane protein with a high molecular weight. It plays a role in lubricating and protecting mucosal epithelium, participates in epithelial cell renewal and differentiation, and regulates cell adhesion, sig
Externí odkaz:
https://doaj.org/article/a2399b4523384a5fa61f1baee1a50368
Autor:
Shabnam Malik, Mohammed Sikander, Natasha Bell, Daniel Zubieta, Maria C. Bell, Murali M. Yallapu, Subhash C. Chauhan
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Ovarian cancer stands as the deadliest gynecologic malignancy, responsible for nearly 65% of all gynecologic cancer-related deaths. The challenges in early detection and diagnosis, coupled with the widespread intraperitoneal spread of cancer
Externí odkaz:
https://doaj.org/article/0e43e92e8c534847a4bbbef07a98032f
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
AbstractBackground The chemotherapy resistance often leads to chemotherapy failure. This study aims to explore the molecular mechanism by which MUC1 regulates paclitaxel resistance in lung adenocarcinoma (LUAD), providing scientific basis for future
Externí odkaz:
https://doaj.org/article/ce78e1fb238942bca79b5cded5cf5199
Autor:
Huilin Cui, Qianqian Yu, Qumiao Xu, Chen Lin, Long Zhang, Wei Ye, Yifei Yang, Sijia Tian, Yilu Zhou, Runzhe Sun, Yongsheng Meng, Ningning Yao, Haizhen Wang, Feilin Cao, Meilin Liu, Jinfeng Ma, Cheng Liao, Ruifang Sun
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundEpidermal growth factor receptor (EGFR) is a key protein in cellular signaling that is overexpressed in many human cancers, making it a compelling therapeutic target. On-target severe skin toxicity has limited its clinical application. Dual
Externí odkaz:
https://doaj.org/article/db6ab132041548648605cce96cddb727
Autor:
Cheryl M. Cameron, Vineet Raghu, Brian Richardson, Leah L. Zagore, Banumathi Tamilselvan, Jackelyn Golden, Michael Cartwright, Robert E. Schoen, Olivera J. Finn, Panayiotis V. Benos, Mark J. Cameron
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSelf-antigens abnormally expressed on tumors, such as MUC1, have been targeted by therapeutic cancer vaccines. We recently assessed in two clinical trials in a preventative setting whether immunity induced with a MUC1 peptide vaccine coul
Externí odkaz:
https://doaj.org/article/a3a7f6fa5d1840b3b25ec451cb78574b
Autor:
Maryam Abtin, Nahid Nafisi, Asghar Hosseinzadeh, Sepideh Kadkhoda, Ramesh Omranipour, Leyla Sahebi, Masoumeh Razipour, Soudeh Ghafouri-Fard, Abbas Shakoori
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 2, Pp 367-375 (2024)
Circular RNAs (circRNAs) characterize a novel kind of regulatory RNAs distinguished by great evolutionary conservation and constancy. Although their exact role in malignancies is not fully understood, they mainly work through specific axes. Circular
Externí odkaz:
https://doaj.org/article/0c8ba7fb37e247c7a34dad53b7e3212f
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Diabetic retinopathy (DR) is the leading cause of blinding eye disease among working adults and is primarily attributed to the excessive proliferation of microvessels, which leads to vitreous hemorrhage and retinal traction, there
Externí odkaz:
https://doaj.org/article/67bb1ec7b72147e4be7ecf6c75991e06
Autor:
Aiqin Zhao, Yunzhi Pan, Yingyin Gao, Zheng Zhi, Haiying Lu, Bei Dong, Xuan Zhang, Meiying Wu, Fenxia Zhu, Sufang Zhou, Sai Ma
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract In contrast to the decreasing trends in developed countries, the incidence and mortality rates of cervical squamous cell carcinoma in China have increased significantly. The screening and identification of reliable biomarkers and candidate d
Externí odkaz:
https://doaj.org/article/042bb3dcc4a44ba39705e9a18abc19b4
Publikováno v:
Клінічна та профілактична медицина, Iss 2, Pp 43-48 (2024)
Introduction. Determining the cause of postnasal drip syndrome can be quite challenging. Nasal septum deformation has been recognized as one possible factor. Understanding the fundamental processes of postnasal drip syndrome is crucial for developing
Externí odkaz:
https://doaj.org/article/fc4055b577c64f8e841b3460df30eb31