Zobrazeno 1 - 10
of 5 810
pro vyhledávání: '"msh2"'
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Candida glabrata is the second most common cause of invasive candidiasis worldwide. In this study, we determined the clinical characteristics and drug sensitivity of C. glabrata isolates and investigated the associations between M
Externí odkaz:
https://doaj.org/article/eb89df6095324f9cb73497848a0f4b5b
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 38, Iss 1 (2024)
AbstractColorectal cancer is one of the most common cancers and a frequent cause of mortality and morbidity. In this study, we aimed to investigate the Mismatch Repair (MMR) gene products of colorectal adenocarcinomas by immunohistochemistry, to inve
Externí odkaz:
https://doaj.org/article/4f6d3937e47242cf929c18cf4a57931c
Autor:
Lan Zhong, Wenxiang Wang, Yuanqiong Duan, Liang Song, Zhanghuan Li, Kaixuan Yang, Qintong Li, Rutie Yin
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundLynch syndrome (LS) is an autosomal dominant inherited disorder caused by mutations in mismatch repair genes. Genetic counseling is crucial for the prevention and treatment of LS, as individuals with these mutations have an increased lifeti
Externí odkaz:
https://doaj.org/article/8ac0b288ed5448b68e773a09e903b4dc
Autor:
Pål Møller, Saskia Haupt, Aysel Ahadova, Matthias Kloor, Julian R. Sampson, Lone Sunde, Toni Seppälä, John Burn, Inge Bernstein, Gabriel Capella, D. Gareth Evans, Annika Lindblom, Ingrid Winship, Finlay Macrae, Lior Katz, Ido Laish, Elez Vainer, Kevin Monahan, Elizabeth Half, Karoline Horisberger, Leandro Apolinário da Silva, Vincent Heuveline, Christina Therkildsen, Charlotte Lautrup, Louise L Klarskov, Giulia Martina Cavestro, Gabriela Möslein, Eivind Hovig, Mev Dominguez-Valentin
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Colorectal cancers (CRCs) in the Lynch syndromes have been assumed to emerge through an accelerated adenoma-carcinoma pathway. In this model adenomas with deficient mismatch repair have an increased probability of acquiring additi
Externí odkaz:
https://doaj.org/article/b927da2164d549d2a1b8caf236ddd5ed
Autor:
Nooshin Nazarinejad, Bahareh Hajikhani, Amir Abbas Vaezi, Farzaneh Firoozeh, Fatemeh Sameni, Somayeh Yaslianifard, Mehdi Goudarzi, Masoud Dadashi
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Deficient DNA mismatch repair (MMR) can cause microsatellite instability (MSI) and is more common in colorectal cancer (CRC) patients. Understanding the carcinogenic mechanism of bacteria and their impact on cancer cells is crucia
Externí odkaz:
https://doaj.org/article/2283b0f5b477476bbaca7f846fa906d8
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 15, Iss 1, Pp 43-48 (2024)
The major mortality factor for women globally is breast cancer, and current treatments have several adverse effects. Hesperetin (HSP) is a flavone that occurs naturally with anti-tumor capabilities and has been investigated as a potential treatment f
Externí odkaz:
https://doaj.org/article/82d969b1cfd848b29869a1d13c399814
Autor:
Yuhan Wang, Zhiyuan Zhang
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Gliosarcoma is a rare subtype of glioblastoma (GBM) with a shorter medical history and a worse prognosis compared to other Grade 4 gliomas. Most gliosarcomas are sporadic, but it is undeniable that a small percentage are linked to germline mutations
Externí odkaz:
https://doaj.org/article/3b57bf9a366744858e93bea4ae625e81
Autor:
Sekine, Shigeki1,2,3 ssekine@ncc.go.jp, Ogawa, Reiko2, Saito, Shinya4, Ushiama, Mineko3,5, Shida, Dai6, Nakajima, Takeshi3,7, Taniguchi, Hirokazu1, Hiraoka, Nobuyoshi1,2,3, Yoshida, Teruhiko3,5, Sugano, Kokichi3,4
Publikováno v:
Histopathology. Mar2017, Vol. 70 Issue 4, p664-669. 6p.
Publikováno v:
Cancer Treatment and Research Communications, Vol 40, Iss , Pp 100826- (2024)
Background: Recently, some evidence emphasized the value of MSH2 and MSH6 inactivation and their hypermutation in predicting different cancers. The present consideration is to evaluate the value of MSH2 and MSH6 protein deficient studied by the immun
Externí odkaz:
https://doaj.org/article/f41982c74328400e8b9387ccf3663af0
Autor:
Seyed Mohsen Mirabdolhosseini, Mohammad Yaghoob Taleghani, Leili Rejali, Hossein Sadeghi, Nayeralsadat Fatemi, Mehdi Tavallaei, Amin Famil Meyari, Narges Saeidi, Pardis Ketabi Moghadam, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Ehsan Nazemalhosseini Mojarad
Publikováno v:
Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Approximately 5% of colorectal cancers (CRCs) are hereditary. Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is the most common form of recognized hereditary CRC. Although Iran, as a developi
Externí odkaz:
https://doaj.org/article/a454974b56704bf9a1743d83cb433cff