Effect of sesamol on damaged peripheral nerves: Evaluation of functional, histological, molecular, and oxidative stress parameters

Autor: Nastaran Amerian, Athar Talebi, Manouchehr Safari, Hamid Reza Sameni, Ali Ghanbari, Parisa Hayat, Moslem Mohammadi, Maryam Ardekanian, Sam Zarbakhsh

Publikováno v: Avicenna Journal of Phytomedicine, Vol 12, Iss 6, Pp 602-613 (2022)

Objective: Peripheral nerve injury is a clinical problem that may cause sensory and motor inabilities. Sesamol is an antioxidant that can help in repairing damaged central nervous system (CNS) and other organs. The present study aimed to investigate

Externí odkaz: https://doaj.org/article/88e62799ee344c37a1966cc82aa7293f

A role for Schwann cell-derived neuregulin-1 in remyelination

Autor: Viktorija Velanac, Michael W. Sereda, Ruth M. Stassart, Dies Meijer, Markus H. Schwab, Bastian G. Brinkmann, Klaus-Armin Nave, Robert Fledrich

Publikováno v: Nature Neuroscience; Vol 16
Nature reviews / Neuroscience 16(1), 48-54 (2012). doi:10.1038/nn.3281
Nature Neuroscience, 16(1), 48-U76. Nature Publishing Group

After peripheral nerve injury, axons regenerate and become remyelinated by resident Schwann cells. However, myelin repair never results in the original myelin thickness, suggesting insufficient stimulation by neuronal growth factors. Upon testing thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0176cddab12324d400af0426f4e98db9