Determination of the healing effect of Piper aduncum (spiked pepper or matico) on human fibroblasts

Autor: Karen Paco, Luis Alberto Ponce-Soto, Marco Lopez-Ilasaca, José L. Aguilar

Publikováno v: Revista Peruana de Medicina Experimental y Salud Pública, Vol 33, Iss 3, Pp 438-47 (2016)

Objectives. To evaluate the healing effect of a Piper aduncum ethanol-water extract on an adult human dermal fibroblast cell line (hDFa). Materials and Methods. After obtaining the extract via solid-liquid extraction, concentration, and lyophilizatio

Externí odkaz: https://doaj.org/article/76a7d4a34e5d4fb9be58e9d98bca696d

Effects of BPA on expression of apoptotic genes and migration of ovine trophectoderm (oTr1) cells during the peri-implantation period of pregnancy

Autor: Amal A. Halawa, Wanjin Tang, Mohammed A Elmetwally, Yasser Y. Lenis, Fuller W. Bazer, Guoyao Wu

Publikováno v: Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A

Bisphenol A (BPA) is an endocrine-disrupting chemical used in the manufacture of many products used daily. In the present study, the effects of BPA (1 × 10 −4 to 1 × 10 -9 M) on migration and on the expression of some apoptotic genes were examine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79679eec55af183f3f39f0f798ac7b33
https://doi.org/10.1016/j.reprotox.2018.12.001

iPS-Derived Early Oligodendrocyte Progenitor Cells from SPMS Patients Reveal Deficient In Vitro Cell Migration Stimulation

Autor: Pedro Carmona-Sáez, Jordi Martorell-Marugán, Elena González-Muñoz, Lidia Lopez-Caraballo

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Cells
Volume 9
Issue 8
Cells, Vol 9, Iss 1803, p 1803 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

This research was funded by Ministerio de Economia y Competitividad Gobierno de Espana (RYC-2014-15410 and SAF2015-66105-R), Fundacion GENZYME, Consejeria Economia y Conocimiento Junta de Andalucia-FEDER (UMA18-FEDERJA-107) and Fundacion Progreso y S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80ecb0b8f7c4f3d42d34ff3ec7f7fb7

Anti-fibrotic effects of pirfenidone and rapamycin in primary IPF fibroblasts and human alveolar epithelial cells

Autor: Maria Molina-Molina, Roger Llatjós, Ignacio Escobar, P. Luburich-Hernaiz, Vanesa Vicens-Zygmunt, E. Sala-Llinas, Jordi Dorca, Ana Montes-Worboys, C. Machahua-Huamani

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-13 (2018)
BMC Pulmonary Medicine
Dipòsit Digital de la UB
Universidad de Barcelona

Background: Pirfenidone, a pleiotropic anti-fibrotic treatment, has been shown to slow down disease progression of idiopathic pulmonary fibrosis (IPF), a fatal and devastating lung disease. Rapamycin, an inhibitor of fibroblast proliferation could be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899bd058433e8630ceaa203696005937
https://doi.org/10.1186/s12890-018-0626-4

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation

Autor: Rayman Choo-Wing, John M. Asara, Dimitrios Anastasiou, Mark J. Arends, Gelareh Zadeh, Adamo Valle, Nikos Koundouros, Yuxiang Zheng, George Poulogiannis, Amit Gupta, Lewis C. Cantley, Yu-Hsin Chiu, Maria Dimitriadi, Sara Anjomani-Virmouni, Sameer Agnihotri

Publikováno v: Gupta, A, Anjomani-Virmouni, S, Koundouros, N, Dimitriadi, M, Choo-Wing, R, Valle, A, Zheng, Y, Chiu, Y-H, Agnihotri, S, Zadeh, G, Wagner, M, M. Asara, J, Anastasiou, D, Arends, M J, Cantley, L C & Poulogiannis, G 2017, ' PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-nitrosylation ', Molecular Cell, vol. 65, no. 6, pp. 999-1013.e7 . https://doi.org/10.1016/j.molcel.2017.02.019

PARK2 is a gene implicated in disease states with opposing responses in cell fate determination, yet its contribution in pro-survival signaling is largely unknown. Here we show that PARK2 is altered in over a third of all human cancers, and its deple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8382cb9e16caada1493c79977d1b5ea
https://doi.org/10.1016/j.molcel.2017.02.019