Zobrazeno 1 - 10
of 25 814
pro vyhledávání: '"mouse models."'
Autor:
Wolfgang Stremmel, Ralf Weiskirchen
Publikováno v:
Livers, Vol 4, Iss 3, Pp 479-494 (2024)
Intestinal mucus serves as the first line barrier within the mucosa to protect against microbiota attack due to its water-repellent properties, which are the result of the high abundance of phosphatidylcholine bound to mucins. A deficiency of mucus p
Externí odkaz:
https://doaj.org/article/139240af546c423dac07acc314fa0fd3
Autor:
Xingshen Li
Publikováno v:
Discover Psychology, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Autism Spectrum Disorder (ASD) presents a significant challenge due to its complex genetic basis and associated comorbidities. Among the genes implicated in ASD, SHANK3 has been identified as a critical player, affecting synaptic structure a
Externí odkaz:
https://doaj.org/article/98b8a3691d0349ee825af5e0d4cd9f40
Autor:
Antonio Cigliano, Isabella Gigante, Marina Serra, Gianpaolo Vidili, Maria M. Simile, Sara Steinmann, Francesco Urigo, Eleonora Cossu, Giovanni M. Pes, Maria P. Dore, Silvia Ribback, Egle P. Milia, Elena Pizzuto, Serena Mancarella, Li Che, Rosa M. Pascale, Gianluigi Giannelli, Matthias Evert, Xin Chen, Diego F. Calvisi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Intrahepatic cholangiocarcinoma (iCCA) is a lethal primary liver tumor characterized by clinical aggressiveness, poor prognosis, and scarce therapeutic possibilities. Therefore, new treatments are urgently needed to render this di
Externí odkaz:
https://doaj.org/article/4358a36380b8455e977ec4053d406fe2
Autor:
Magali Boucher, Cyndi Henry, Louis Gélinas, Rosalie Packwood, Andrés Rojas-Ruiz, Liah Fereydoonzad, Percival Graham, Ynuk Bossé
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The level of airway constriction in thin slices of lung tissue is highly variable. Owing to the labor-intensive nature of these experiments, determining the number of airways to be analyzed in order to allocate a reliable value of constricti
Externí odkaz:
https://doaj.org/article/637cd8a18c8343308419698a40b24834
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 1729-1737 (2024)
Hui Tang,1,* Xiaoxia Ding,2,3,* Youming Huang,2 Danfeng Xu,2 Yibin Fan1,2 1Graduate School of Clinical Medicine, Bengbu Medical College, Bengbu, 233030, People’s Republic of China; 2Center for Plastic & Reconstructive Surgery, Department of
Externí odkaz:
https://doaj.org/article/18933d2536d54bf5802dec6d4a8cfb9b
Autor:
Ruoshi Xu, Xiaohan Zhang, Weimin Lin, Yushun Wang, Danting Zhang, Shuang Jiang, Linfeng Liu, Jiaying Wang, Xutao Luo, Xiao Zhang, Junjun Jing, Quan Yuan, Chenchen Zhou
Publikováno v:
Advanced Science, Vol 11, Iss 47, Pp n/a-n/a (2024)
Abstract Oral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural tee
Externí odkaz:
https://doaj.org/article/2b2c09057e8a4a5e8bf33a0ef3f09f51
Autor:
Tove Selvin, Malin Berglund, Anders Åkerström, Marco Zia, Jakob Rudfeldt, Malin Jarvius, Rolf Larsson, Claes R Andersson, Mårten Fryknäs
Publikováno v:
SLAS Technology, Vol 29, Iss 6, Pp 100232- (2024)
To facilitate the translation of immunotherapies from bench to bedside, predictive preclinical models are essential. We developed the in vivo immuno-oncology Hollow Fiber Assay (HFA) to bridge the gap between simpler cell-based in vitro assays and mo
Externí odkaz:
https://doaj.org/article/d2e6640e28ad4e36aa4dfe94b2089f19
Autor:
Yuji Shi, Patricia Perez‐Bonilla, Xian Chen, Kelly Tam, Mackenzie Marshall, Jeffrey Morin, Brianna LaViolette, Nouaying R. Kue, Federico Damilano, Russell A. Miller, Bei B. Zhang, Rachel J. Roth Flach, Dinesh Hirenallur‐Shanthappa
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 23 (2024)
Background Heart failure with preserved ejection fraction (HFpEF) currently accounts for more than half of patients with HF, with limited approved evidence‐based therapies. HFpEF is a complex multifactorial disease associated with hypertension, obe
Externí odkaz:
https://doaj.org/article/c52cdc9ad89248bdb1fd6e12ca76e8aa
Autor:
Wei Yang, Chen Zhang, Li-Bo Liu, Zhan-Zhan Bian, Jia-Tong Chang, Dong-Ying Fan, Na Gao, Pei-Gang Wang, Jing An
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
During its global epidemic, Zika virus (ZIKV) attracted widespread attention due to its link with various severe neurological symptoms and potential harm to male fertility. However, the understanding of how ZIKV invades and persists in the male repro
Externí odkaz:
https://doaj.org/article/72c87595558742629fc139c515bf4759