Zobrazeno 1 - 10
of 245
pro vyhledávání: '"mouse double minute 2"'
Autor:
Chinchilla-Tábora LM, Ortiz Rodríguez-Parets J, Otero-Rodríguez Á, Ruiz Martín L, Paniagua Escudero JC, Navarro Martín LM, Cigarral García B, Nieto Palacios A, González Morais I, Sayagués JM, Ludeña de la Cruz MD
Publikováno v:
International Medical Case Reports Journal, Vol Volume 16, Pp 709-714 (2023)
Luis Miguel Chinchilla-Tábora,1 Javier Ortiz Rodríguez-Parets,1 Álvaro Otero-Rodríguez,2 Laura Ruiz Martín,2 Juan Carlos Paniagua Escudero,3 Luis Miguel Navarro Martín,4 Belén Cigarral García,4 Adelaida Nieto Palacios,5 Idalia González Morai
Externí odkaz:
https://doaj.org/article/793722138811481095cac935020e4a26
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract Objective It has been evidenced that microRNAs (miRs) exert crucial effects on acute liver failure (ALF), while the detailed function of miR‐450b‐5p in ALF progression remained obscure. The purpose of this research was to unravel the reg
Externí odkaz:
https://doaj.org/article/853b28283e514f2bb7428cb50a7dea97
Autor:
Yanting Zhu, Qianqian Zhang, Xin Yan, Lu Liu, Cui Zhai, Qingting Wang, Limin Chai, Manxiang Li
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-9 (2021)
Pulmonary arterial hypertension is a devastating pulmonary vascular disease, in which the pathogenesis is complicated and unclear. Pulmonary arterial smooth muscle cells (PASMCs) proliferation is a key pathological feature of pulmonary arterial hyper
Externí odkaz:
https://doaj.org/article/a3745575a43c429f856f2f8d75238105
Akademický článek
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Autor:
Yasmine M. Abdel Aziz, Gehad Lotfy, Mohamed M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany, Saied M. Soliman, Marwa M. Abu-Serie, Mohamed Teleb, Sammer Yousuf, Alexander Dömling, Luis R. Domingo, Assem Barakat
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The tumor resistance to p53 activators posed a clinical challenge. Combination studies disclosed that concomitant administration of Bcl2 inhibitors can sensitize the tumor cells and induce apoptosis. In this study, we utilized a rapid synthetic route
Externí odkaz:
https://doaj.org/article/1550dff8a8cb47f0a1a434fd5e635b7f
Autor:
Nazanin Jalilian, Yosra Maleki, Ebrahim Shakiba, Mozafar Aznab, Ziba Rahimi, Mehdi salimi, Zohreh Rahimi
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 15, Iss 3 (2021)
Background: Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. The MDM2 and p53 are interacting proteins that play crucial roles in cell biology. Genetic variations of p53 and MDM2 (p53 codon 72 and MDM2 SNP30) have been identi
Externí odkaz:
https://doaj.org/article/773502b0b5bd4d4bb21ae2f1877b4395
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-19 (2019)
Abstract Background Neural tube defects (NTDs) are common congenital malformations resulting in failure of the neural tube closure during early embryonic development. Although it is known that maternal folate deficiency increases the risk of NTDs, th
Externí odkaz:
https://doaj.org/article/4bf258fef3704c5cafe4ddcfcc58edee
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Aiting Wang, Mengdi Yang, Rui Liang, Fangming Zhu, Fuxiang Zhu, Xinnan Liu, Yichao Han, Ruirong Lin, Xiaoxia Wang, Dan Li, Hecheng Li, Xiaojun Yuan, Hui Zhao, Bin Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Regulatory T cells (Treg cells) are essential for maintaining immune tolerance, and the dysfunction of Treg cells may cause autoimmune diseases and tumors. Forkhead box P3 (FOXP3) is the key transcription factor controlling Treg cell development and
Externí odkaz:
https://doaj.org/article/6c7baed319ee4a789a50f36bd1a926d2
Autor:
Jinkyung Kim, Sung-Min Kang, Su Young Oh, Soo Hyun Kang, Inhan Lee, Jae Chan Hwang, Heon-Jin Lee, So-Young Choi, Su-Hyung Hong
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 5, Pp 1869-1881 (2018)
Background/Aims: The functional relevance of early growth response-1 (EGR1) on cancer invasion remains controversial. The effect of EGR1 on the expression of MMP9, which is important for HNSCC invasion, is still disputed. There is no previous data sh
Externí odkaz:
https://doaj.org/article/92f72759c59c497480b58e915aa6d4cf