Zobrazeno 1 - 10
of 610
pro vyhledávání: '"motoneuron disease"'
Publikováno v:
Foods, Vol 13, Iss 14, p 2257 (2024)
Cramp–fasciculation syndrome (CFS) is a rare and benign neuromuscular disorder that may initially masquerade as motor neuron disease/amyotrophic lateral sclerosis. While CFS may have a familial disposition, we report on cases associated with high c
Externí odkaz:
https://doaj.org/article/0646593d178e47f1a6f79b54bb050083
Autor:
Nadja Ratia, Edouard Palu, Hanna Lantto, Emil Ylikallio, Ritva Luukkonen, Anu Suomalainen, Mari Auranen, Päivi Piirilä
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionSpinal muscular atrophy, Jokela type (SMAJ) is a rare autosomal dominantly hereditary form of spinal muscular atrophy caused by a point mutation c.197G>T in CHCHD10. CHCHD10 is known to be involved in the regulation of mitochondrial funct
Externí odkaz:
https://doaj.org/article/e7cdf08fadf84726b0c12e38e21565db
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord. The causes of ALS are not fully understood. About 10% of ALS cases were associated with genetic facto
Externí odkaz:
https://doaj.org/article/6e343e5391dd4453bc028fef363440bb
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-32 (2022)
Abstract Background Major efforts have been made in the last decade to develop and improve therapies for proximal spinal muscular atrophy (SMA). The introduction of Nusinersen/Spinraza™ as an antisense oligonucleotide therapy, Onasemnogene abeparvo
Externí odkaz:
https://doaj.org/article/aacdb715c31044bfbb97d4bce198a0c4
Autor:
Albert J. B. Lee, Tyler E. Kittel, Renaid B. Kim, Thao-Nguyen Bach, Tian Zhang, Cassie S. Mitchell
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
IntroductionAmyotrophic Lateral Sclerosis (ALS) is a paralyzing, multifactorial neurodegenerative disease with limited therapeutics and no known cure. The study goal was to determine which pathophysiological treatment targets appear most beneficial.M
Externí odkaz:
https://doaj.org/article/6a6ee18d61ff4ee9a3771fa4782d0b5c
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Anna Martínez-Muriana, Diego Pastor, Renzo Mancuso, Amaya Rando, Rosario Osta, Salvador Martínez, Rubèn López-Vales, Xavier Navarro
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Background The simultaneous contribution of several etiopathogenic disturbances makes amyotrophic lateral sclerosis (ALS) a fatal and challenging disease. Here, we studied two different cell therapy protocols to protect both central and peri
Externí odkaz:
https://doaj.org/article/8d33161732da499ba5e50cfa37ffd723
Autor:
Rosario Gulino
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4613 (2023)
Recent evidence has supported the hypothesis that amyotrophic lateral sclerosis (ALS) is a multi-step disease, as the onset of symptoms occurs after sequential exposure to a defined number of risk factors. Despite the lack of precise identification o
Externí odkaz:
https://doaj.org/article/fb2b4ab4db0f4b8687d96b2aeb948abd
Publikováno v:
Brain Sciences, Vol 12, Iss 11, p 1558 (2022)
Superficial siderosis of the central nervous system (SS-CNS) is a rare condition characterized by a hemosiderin accumulation along the subpial surfaces and arises from an intermittent chronic bleeding in the subarachnoid space usually as a result of
Externí odkaz:
https://doaj.org/article/18f7155c696b483eb5c19989ee24ee49