Zobrazeno 1 - 10
of 239
pro vyhledávání: '"monoiodoacetate"'
Publikováno v:
Life, Vol 14, Iss 8, p 983 (2024)
Pain is the primary clinical indication of osteoarthritis (OA), and behavioral assessments in rodent pain models are widely used to understand pain patterns. These preclinical pain assessments can also help us to understand the effectiveness of emerg
Externí odkaz:
https://doaj.org/article/872a207e77524e099446db4f018ba63f
Autor:
George Bică, Otilia-Constantina Rogoveanu, Florin-Liviu Gherghina, Cătălina-Gabriela Pisoschi, Sandra-Alice Buteică, Cristina-Elena Biță, Iulia-Alexandra Paliu, Ion Mîndrilă
Publikováno v:
Biology, Vol 13, Iss 5, p 331 (2024)
Iron oxide nanoparticles (IONPs) represent an important advance in the field of medicine with application in both diagnostic and drug delivery domains, offering a therapeutic approach that effectively overcomes physical and biological barriers. The c
Externí odkaz:
https://doaj.org/article/aba30c22f1044ceda5b993874f82531f
Autor:
Takahito Arai, Miyako Suzuki-Narita, Jun Takeuchi, Ikuko Tajiri, Kazuhide Inage, Yuya Kawarai, Yawara Eguchi, Yasuhiro Shiga, Takashi Hozumi, Geundong Kim, Ryuto Tsuchiya, Takuma Otagiri, Tomohito Mukaihata, Takahisa Hishiya, Noriyasu Toshi, Kohei Okuyama, Soichiro Tokeshi, Takeo Furuya, Satoshi Maki, Yusuke Matsuura, Takane Suzuki, Junichi Nakamura, Shigeo Hagiwara, Seiji Ohtori, Sumihisa Orita
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Diclofenac etalhyaluronate (DF-HA) is a recently developed analgesic conjugate of diclofenac and hyaluronic acid that has analgesic and anti-inflammatory effects on acute arthritis. In this study, we investigated its analgesic eff
Externí odkaz:
https://doaj.org/article/f2beb6adf9e14b90be82d5330cf7bc94
Autor:
Satoshi Yoh, Yuya Kawarai, Shigeo Hagiwara, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Takane Suzuki, Tsutomu Akazawa, Yuki Shiko, Yohei Kawasaki, Seiji Ohtori
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Monoiodoacetate (MIA)-induced arthritis models are used widely in osteoarthritis (OA) research to develop effective conservative treatments for hip OA, as an alternative to joint replacement surgery. In joint OA models, such as th
Externí odkaz:
https://doaj.org/article/2b090adb3c6d4e98bdc4414235c6f03f
Akademický článek
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Autor:
Adithan Aravinthan, Mohammad Amjad Hossain, Bumseok Kim, Chang-Won Kang, Nam Soo Kim, Ki-Chul Hwang, Jong-Hoon Kim
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 2, Pp 287-294 (2021)
Background: Ginsenoside Rb1 (G-Rb1), one of the major active compounds in Panax ginseng, has already been shown to reduce inflammation in various diseases. Osteoarthritis (OA) has traditionally been considered a degenerative disease with degradation
Externí odkaz:
https://doaj.org/article/3a2d94f7e1de4bf881a159e8e389cbbb
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Osteoarthritis (OA) associated pain (OA-pain) is a significant global problem. OA-pain limits limb use and mobility and is associated with widespread sensitivity. Therapeutic options are limited, and the available options are often associated with ad
Externí odkaz:
https://doaj.org/article/3ba76ba42a0b45369aa9586c11660597
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Giada Amodeo, Silvia Franchi, Giulia Galimberti, Laura Comi, Simona D’Agnelli, Marco Baciarello, Elena Giovanna Bignami, Paola Sacerdote
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2847 (2022)
Knee osteoarthritis is a common cause of pain and disability in old subjects. Pain may predispose to the development of frailty. Studies on mechanisms underlying pain in osteoarthritis models during aging are lacking. In this work, we used the monoso
Externí odkaz:
https://doaj.org/article/0c4fd6e6e83c4f7185c6d7ca1daf0a8f
Autor:
Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe, Ai Takahashi, Kazuya Honjoh, Hideaki Nakajima, Hisashi Oki, Yasuo Kokubo, Akihiko Matsumine
Publikováno v:
BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Previous basic research and clinical studies examined the effects of mesenchymal stem cells (MSCs) on regeneration and maintenance of articular cartilage. However, our pilot study suggested that MSCs are more effective at suppress
Externí odkaz:
https://doaj.org/article/15ee7601a938487f983d14842ae03ea3