Zobrazeno 1 - 10
of 189
pro vyhledávání: '"monoamine reuptake inhibitor"'
Autor:
Kosuke Shirose, Masanobu Yoshikawa, Takugi Kan, Masaaki Miura, Mariko Watanabe, Mitsumasa Matsuda, Hiroyuki Kobayashi, Mitsuru Kawaguchi, Kenji Ito, Takeshi Suzuki
Publikováno v:
Biology, Vol 13, Iss 9, p 679 (2024)
Xerostomia induced by antidepressants such as imipramine has long been thought to be due to their anticholinergic effects. However, even antidepressants with low anticholinergic effects may have a high incidence of xerostomia. In salivary glands, nor
Externí odkaz:
https://doaj.org/article/7cc07a6f6ae549649a389eafab6e8ffd
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Current Pharmaceutical Design. 26:244-252
In this narrative review, we intended to summarize the evidence of pharmacological and somatic treatment choices for treatment-resistant depression (TRD). There are several types of therapeutic strategies to improve inadequate response to antidepress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870d3a5d5d172d055630cac2b7121227
https://doi.org/10.2174/1381612826666200110101604
https://doi.org/10.2174/1381612826666200110101604
Autor:
Haibo Zhu, Wenyan Wang, Chunjie Sha, Wei Guo, Chunmei Li, Fengjuan Zhao, Hongbo Wang, Wanglin Jiang, Jingwei Tian
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2ec5f0cf786bd0b50f519b049ffa1b
https://doi.org/10.3389/fphar.2021.741794
https://doi.org/10.3389/fphar.2021.741794
Autor:
Katherine Conant, Ismary Blanco
Publikováno v:
Eur J Neurosci
Emerging evidence suggests that extracellular matrix (ECM) alterations occur with stress. Specifically, increases in perineuronal net (PNN) deposition have been observed in rodents exposed to chronic corticosterone or persistent social defeat stress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfff1bb96a3654303a1010c014843d7
https://pubmed.ncbi.nlm.nih.gov/32673433
https://pubmed.ncbi.nlm.nih.gov/32673433
Autor:
Kwang-Hee Shin, Soo Hyeon Bae, Yoojeong Jang, Anhye Kim, Hyeon-Cheol Jeong, Jung-Woo Bae, Sooyeun Lee
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 618 (2019)
Pharmaceutics
Volume 11
Issue 11
Pharmaceutics
Volume 11
Issue 11
Tramadol is a &mu
opioid receptor agonist and a monoamine reuptake inhibitor. O-desmethyltramadol (M1), the major active metabolite of tramadol, is produced by CYP2D6. A physiologically-based pharmacokinetic model was developed to predict change
opioid receptor agonist and a monoamine reuptake inhibitor. O-desmethyltramadol (M1), the major active metabolite of tramadol, is produced by CYP2D6. A physiologically-based pharmacokinetic model was developed to predict change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbec662699ac184823546050564619a
https://www.mdpi.com/1999-4923/11/11/618
https://www.mdpi.com/1999-4923/11/11/618
Autor:
Anthony McKinney, Michelle E. Lee, Amir H. Rezvani, Corinne Wells, Susan Slade, Jed E. Rose, Edward D. Levin
Publikováno v:
Nicotine Tob Res
Introduction Existing treatments can aid tobacco smoking cessation, but they have low efficacy. Because there is a network of neural systems involved in tobacco addiction, combination treatments may provide greater efficacy. Chronic nicotine and amit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a03b9d629cc27302f8c249e813db82d
https://europepmc.org/articles/PMC7297093/
https://europepmc.org/articles/PMC7297093/
Autor:
Cienna L. Nielsen, Christopher K. Surratt, Nicholas E. Wolters, Gianluigi Tanda, Maddalena Mereu, Rehana K. Leak, Martín Indarte, Jessica E. Jorvig, Elizabeth Dallman, Laura M. Geffert, Mary Ellen Amos, Hailey Choi, Caitlin A. Munro, Ruben I. Goldstein, Jonathan L. Katz, Jeffry D. Madura, Jeffery N. Talbot
Publikováno v:
Pharmacol Biochem Behav
Rational design of lead compounds targeting monoamine transporters (MATs) is critical to developing novel therapeutics to treat psychiatric disorders including depression and substance abuse. A 3-D dopamine transporter (DAT) computer model was used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91740c0c191642d61b94a46a13ee6f7
https://doi.org/10.1016/j.pbb.2016.08.007
https://doi.org/10.1016/j.pbb.2016.08.007