Zobrazeno 1 - 10
of 48
pro vyhledávání: '"molekulare Evolution"'
Site-specific tyrosine-type recombinases are effective tools for genome engineering, with the first engineered variants having demonstrated therapeutic potential. So far, adaptation to new DNA target site selectivity of designerrecombinases has been
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91838
https://tud.qucosa.de/api/qucosa%3A91838/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91838/attachment/ATT-0/
Autor:
Lansing, Felix, Mukhametzyanova, Liliya, Rojo-Romanos, Teresa, Iwasawa, Kentaro, Kimura, Masaki, Paszkowski-Rogacz, Maciej, Karpinski, Janet, Grass, Tobias, Sonntag, Jan, Schneider, Paul Martin, Günes, Ceren, Hoersten, Jenna, Schmitt, Lukas Theo, Rodriguez-Muela, Natalia, Knöfler, Ralf, Takebe, Takanori, Buchholz, Frank
Despite advances in nuclease-based genome editing technologies, correcting human disease-causing genomic inversions remains a challenge. Here, we describe the potential use of a recombinase-based system to correct the 140 kb inversion of the F8 gene
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91150
https://tud.qucosa.de/api/qucosa%3A91150/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91150/attachment/ATT-0/
Autor:
Sun, Jianfeng
We have built on deep residual neural networks and coevolutionary features to develop two novel deep-learning-based systems, DeepHelicon and DeepTMInter, for sequence-based prediction of residue contacts and interaction sites in TM proteins, respecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______518::34a834a0a8143120f08c7d5cb31453b4
https://mediatum.ub.tum.de/1577512
https://mediatum.ub.tum.de/1577512
Autor:
Wesseling, Anne-Maria
The specialized metabolism of plants (also called secondary metabolism) and the evolution of proteins are two fascinating and active fields of biological research which overlap in the subject of the present doctoral thesis: pyrrolizidine alkaloid bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::198c471326e2b7ed2b6e6dd7b23ca43f
http://macau.uni-kiel.de/receive/dissertation_diss_00020757
http://macau.uni-kiel.de/receive/dissertation_diss_00020757
Autor:
Worst, Emanuel Gregor
Seit Beginn des Lebens entstehen durch Reproduktion, Variation und Selektion immer neue Spezies. Stetige Erneuerung statt Stagnation ist Teil der Evolution. Ein Modellsystem aus linearen DNA-Molekülen wurde entwickelt, in dem durch spontane Ligation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5df6bd5fb520746f6230b5d6139cb7
Autor:
Shen, Hong
Für eine umfassende Untersuchung der Phylogenie der Decapoda wurden von mir die mitochondrialen Genome von 13 Dekapoden sequenziert. Zusammen mit den in der GenBank verfügbaren Sequenzen von 31 Dekapoden und dem von der Universität Bonn zur Verfü
Externí odkaz:
http://edoc.hu-berlin.de/18452/17157
Autor:
Alva Kullanja, Vikram
Though seemingly endless, the diversity of proteins in nature is in fact narrowly confined. Many proteins share recognizable similarity in sequence and structure, since they arose by amplification, recombination, and divergence from a basic complemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______707::1c37efe1b1e0d6919357fcc37caba889
https://hdl.handle.net/10900/49752
https://hdl.handle.net/10900/49752