Zobrazeno 1 - 10
of 1 557
pro vyhledávání: '"molecular targeting"'
Autor:
Aiman Al-Ruwishan, Bushra Amer, Ahmed Salem, Ahmed Abdi, Namoonga Chimpandu, Abdelmonem Esa, Alexandros Melemenis, Muhammad Zubair Saleem, Roselit Mathew, Yaser Gamallat
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8340-8367 (2024)
Despite recent advancements in technology, breast cancer still poses a significant threat, often resulting in fatal consequences. While early detection and treatments have shown some promise, many breast cancer patients continue to struggle with the
Externí odkaz:
https://doaj.org/article/b2c40c9c36904375920d6e62cd7b6769
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Bevacizumab, a humanized monoclonal antibody targeting vascular endothelial growth factor (VEGF), was the first anti-angiogenic agent incorporated into metastatic colorectal cancer treatment strategies and demonstrated broad-spectrum anti-tumor effic
Externí odkaz:
https://doaj.org/article/81669ddae2ce4160bbcd33d263298315
A novel translational model of atherosclerosis, the ex vivo pump-perfused amputated human limb model
Autor:
Adam Hartley, Jonathan Afoke, Guiqing Liu, Samuel Owen, Reza Hajhosseiny, Kimberly Hassen, Prakash Punjabi, Dorian Haskard, Joseph Shalhoub, Ramzi Khamis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The preclinical study of atherosclerosis has traditionally centred around the use of small animal models, translating to large animal models, prior to first-in-man studies. We propose to disrupt this paradigm by designing an ex vivo pump per
Externí odkaz:
https://doaj.org/article/a21a5569c1134a95a7c1d0b93def871c
Autor:
Huizi Li, Jin Liu, Jie Lai, Xinyao Su, Xiaofeng Wang, Jiaqing Cao, Shengxun Mao, Tong Zhang, Qiuping Gu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Accumulating evidence indicated that HHEX participated in the initiation and development of several cancers, but the potential roles and mechanisms of HHEX in hepatocellular carcinoma (HCC) were largely unclear. Cancer stem cells (CSCs) are
Externí odkaz:
https://doaj.org/article/7d3074e505ef40c29486c815df8af649
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35723- (2024)
Tropomyosin (TPM) is an important regulatory protein that binds to actin in fine myofilaments, playing a crucial role in the regulation of muscle contraction. TPM3, as one of four tropomyosin genes, is notably prevalent in eukaryotic cells. Tradition
Externí odkaz:
https://doaj.org/article/c3b3c8bb90014a2e9962652f1ea36201
Autor:
Chihiro Mimura, Tatsuya Nagano, Nanako Miwa, Kanoko Matsumura, Jun Yamada, Hiroki Satoh, Ratoe Suraya, Daisuke Hazama, Daisuke Tamura, Masatsugu Yamamoto, Motoko Tachihara, Yoshihiro Nishimura, Kazuyuki Kobayashi
Publikováno v:
Thoracic Cancer, Vol 15, Iss 9, Pp 722-729 (2024)
Abstract Background Skin disorders are the most common side effect associated with epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) therapy. It is important to manage skin lesions. Adapalene has been used to treat skin lesion
Externí odkaz:
https://doaj.org/article/ed68ecb858704cc7a49655e82b32b61b
Autor:
Chen, Anjie a, b, 1, Li, Sixin a, b, 1, Gui, Jiandong a, b, 1, Zhou, Hangsheng a, b, 1, Zhu, Lijie a, ⁎⁎, Mi, Yuanyuan a, ⁎
Publikováno v:
In Heliyon 15 August 2024 10(15)
Autor:
Rintaro Moroi, Yoichi Kakuta, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Yoshitaka Kinouchi, Atsushi Masamune
Publikováno v:
JGH Open, Vol 8, Iss 6, Pp n/a-n/a (2024)
Abstract Background and Aim The number of older patients with ulcerative colitis is increasing; however, limited data exist regarding the differences between elderly‐ and non‐elderly‐onset ulcerative colitis. We aimed to compare the clinical pr
Externí odkaz:
https://doaj.org/article/b2fb6884ea0e49d4ad21326984fc222c
Autor:
Rintaro Moroi, Yoichi Kakuta, Taku Obara, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Yoshitaka Kinouchi, Atsushi Masamune
Publikováno v:
JGH Open, Vol 7, Iss 10, Pp 682-689 (2023)
Abstract Background and Aim There is a scarcity of data on long‐term outcomes in patients with new‐onset ulcerative colitis (UC) in the era of biologics. We aimed to clarify the long‐term prognosis of UC and the clinical practice of prescriptio
Externí odkaz:
https://doaj.org/article/19ea21790c3346feb16787bd73e83173
Autor:
Rizky Nurdiansyah, Agus Budiawan Naro Putra, Ainun Nadhifah, Erika Chriscensia, Ulung Khoe Gondo Kusumo, Stephanie Angela Yosiano, Anastasia Beatrix Musung, Sintikhe A Wenas, Steve Makalew, Patricia Lovina, Intani Quarta Lailaty, Fransisca Aurelia Rahmad, Fandi Sutanto, Pietradewi Hartrianti
Publikováno v:
Pharmaceutical Sciences, Vol 29, Iss 4, Pp 448-458 (2023)
Background: The exploration of bryophytes biodiversity in Indonesia due to its abundance and the bioactivity of its phytochemical content, such as alkaloids and polyphenols, has received increased interest. Despite some species proven to possess phar
Externí odkaz:
https://doaj.org/article/0f14361f13f447baa874b2d1caae1fb5