Zobrazeno 1 - 10
of 1 277
pro vyhledávání: '"molecular signature"'
Autor:
Ruhao Wu, Ge Zhang, Mingzhou Guo, Yue Li, Lu Qin, Tianci Jiang, Pengfei Li, Yu Wang, Ke Wang, Yize Liu, Zhiqiu He, Zhe Cheng
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)
Abstract Pulmonary arterial hypertension (PAH) is a progressive and rapidly fatal disease with an intricate etiology. Identifying biomarkers for early PAH lesions based on the exploration of subtle biological processes is significant for timely diagn
Externí odkaz:
https://doaj.org/article/9a39d49464f742fa95c4fea841bd7cff
Autor:
Huang Q, Huang XY, Xue YT, Wu XH, Wu YP, Ke ZB, Kang Z, Xu YC, Chen DN, Wei Y, Xue XY, Huang ZY, Xu N
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7017-7036 (2024)
Qi Huang,1– 3,* Xu-Yun Huang,1,2,* Yu-Ting Xue,1,2,* Xiao-Hui Wu,1,2,* Yu-Peng Wu,1,2,* Zhi-Bin Ke,1,2 Zhen Kang,1,2 Yi-Cheng Xu,1,2 Dong-Ning Chen,1,2 Yong Wei,1,2 Xue-Yi Xue,1,2 Zhi-Yang Huang,3 Ning Xu1,2,4 1Department of Uro
Externí odkaz:
https://doaj.org/article/33a95eedb038465288b2592e28d56f3f
Autor:
Zhiwei Wang, Zhiyan Weng, Luping Lin, Xianyi Wu, Wenju Liu, Yong Zhuang, Jinliang Jian, Changhua Zhuo
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Gastric cancer is a significant global health concern with complex molecular underpinnings influencing disease progression and patient outcomes. Various molecular drivers were reported, and these studies offered potential avenues for targete
Externí odkaz:
https://doaj.org/article/536e001c65e2429d9bc6600c5f809200
Autor:
Esteban Cortes Garcia, Alessia Giarraputo, Maud Racapé, Valentin Goutaudier, Cindy Ursule-Dufait, Pierre de la Grange, Lucie Adoux, Marc Raynaud, Clément Couderau, Fariza Mezine, Jessie Dagobert, Oriol Bestard, Francesc Moreso, Jean Villard, Fabian Halleck, Magali Giral, Sophie Brouard, Richard Danger, Pierre-Antoine Gourraud, Marion Rabant, Lionel Couzi, Moglie Le Quintrec, Nassim Kamar, Emmanuel Morelon, François Vrtovsnik, Jean-Luc Taupin, Renaud Snanoudj, Christophe Legendre, Dany Anglicheau, Klemens Budde, Carmen Lefaucheur, Alexandre Loupy, Olivier Aubert
Publikováno v:
Transplant International, Vol 37 (2024)
Recently, interest in transcriptomic assessment of kidney biopsies has been growing. This study investigates the use of NGS to identify gene expression changes and analyse the pathways involved in rejection. An Illumina bulk RNA sequencing on the pol
Externí odkaz:
https://doaj.org/article/9ecc3009d82f4404afee19ecf718e603
Publikováno v:
Physiological Reports, Vol 12, Iss 11, Pp n/a-n/a (2024)
Abstract The bronchoalveolar organoid (BAO) model is increasingly acknowledged as an ex‐vivo platform that accurately emulates the structural and functional attributes of proximal airway tissue. The transition from bronchoalveolar progenitor cells
Externí odkaz:
https://doaj.org/article/cd80d819e9604864aeae97dc2fe94a45
Autor:
Mehran Radak, Hossein Fallahi
Publikováno v:
Global Medical Genetics, Vol 10, Iss 04, Pp 339-344 (2023)
This review article discusses the epigenetic regulation of quiescent stem cells. Quiescent stem cells are a rare population of stem cells that remain in a state of cell cycle arrest until activated to proliferate and differentiate. The molecular sign
Externí odkaz:
https://doaj.org/article/fdfbe1b2e1a94da4bac4fcf7a733c777
Autor:
Jeffrey R. Curtis, Vibeke Strand, Steven J. Golombek, George A. Karpouzas, Lixia Zhang, Angus Wong, Krishna Patel, Jennifer Dines, Viatcheslav R. Akmaev
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 1, Pp 61-77 (2023)
Abstract Introduction Clinical guidelines offer little guidance for treatment selection following inadequate response to conventional synthetic disease-modifying antirheumatic drug (csDMARD) in rheumatoid arthritis (RA). A molecular signature respons
Externí odkaz:
https://doaj.org/article/fe1216b916824c379498e0495b271723
Autor:
Han Gao, Huixin Li, Chen Lin, Pedro J.J. Alvarez, Caroline A. Masiello, Dongqiang Zhu, Ao Kong, Xiaolei Qu
Publikováno v:
Eco-Environment & Health, Vol 1, Iss 4, Pp 212-218 (2022)
The concentration and molecular composition of soil organic matter (SOM) are important factors in mitigation against climate change as well as providing other ecosystem services. Our quantitative understanding of how land use influences SOM molecular
Externí odkaz:
https://doaj.org/article/202ccf45c80445cfba826e192c21586f
Autor:
José Luis García-Giménez, Elena R. García-Trevijano, Ana I. Avilés-Alía, José Santiago Ibañez-Cabellos, Miquel Bovea-Marco, Teresa Bas, Federico V. Pallardó, Juan R. Viña, Rosa Zaragozá
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background Limb-girdle muscular dystrophy (LGMD) is a rare neuromuscular disease including a growing and heterogeneous number of subtypes with variable phenotype. Their clinical and histopathological characteristics frequently overlap with o
Externí odkaz:
https://doaj.org/article/83e53770d7ef42e49a96358ffec61d31
Autor:
Stanley Cohen, Jeffrey R. Curtis, Theodore Mellors, Lixia Zhang, Johanna B. Withers, Alex Jones, Susan D. Ghiassian, Viatcheslav R. Akmaev
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 1, Pp 1-6 (2022)
Abstract A 2021 study described the development and validation of a blood-based precision medicine test called the molecular signature response classifier (MSRC) that uses 23 features to identify rheumatoid arthritis (RA) patients who are likely nonr
Externí odkaz:
https://doaj.org/article/b3fadc1547454009bb794c3aaa255287