Zobrazeno 1 - 10
of 2 724
pro vyhledávání: '"molecular profiling"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Sarcomas, malignant tumors from mesenchymal tissues, exhibit poor prognosis despite advancements in treatment modalities such as surgery, radiotherapy, and chemotherapy, with doxorubicin being a cornerstone treatment. Resistance to doxorubic
Externí odkaz:
https://doaj.org/article/21f890e2a3414a9498dfc915e001c148
Autor:
Daniel Netto, Melissa Frizziero, Victoria Foy, Mairéad G. McNamara, Alison Backen, Richard A. Hubner
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 5206-5223 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a significant cause of cancer-associated mortality, with a rising global incidence. A paucity of strong predictive risk factors mean screening programmes are difficult to implement. Historically, a lack of i
Externí odkaz:
https://doaj.org/article/82cdbede92d547bc8b5e3d4f02cac346
Autor:
Amanda J. Nguyen, MD, Zachary C. Fogarty, MS, Jaime Davila, PhD, Svetomir N. Markovic, MD, PhD, Chen Wang, PhD, Ruifeng Guo, MD, PhD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 189-191 (2024)
Externí odkaz:
https://doaj.org/article/1ed0d3bd581c490aaa7556df85763474
Autor:
Nathaniel Grabill, MD, Mena Louis, DO, Mariah Cawthon, MD, Claudia Gherasim, MD, James Chambers, MD
Publikováno v:
Radiology Case Reports, Vol 19, Iss 12, Pp 6016-6026 (2024)
Adenosquamous carcinoma of the pancreas (ASCP) is a rare and aggressive variant of pancreatic cancer, characterized by both adenocarcinoma and squamous cell carcinoma components. It presents significant diagnostic and therapeutic challenges due to it
Externí odkaz:
https://doaj.org/article/784af63923114cdf8e71bd5db5955890
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 8, Pp 2039-2058 (2024)
Abstract Skin cancer is the most common cancer type in the USA, with over five million annually treated cases and one in five Americans predicted to develop the disease by the age of 70. Skin cancer can be classified as melanoma or non-melanoma (NMSC
Externí odkaz:
https://doaj.org/article/1485b9caf5cb41549d6d4222a2b84c07
Autor:
Christopher Godina, Mattias Belting, Johan Vallon-Christersson, Karolin Isaksson, Ana Bosch, Helena Jernström
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Combining information from the tumor microenvironment (TME) with PAM50 Risk of Recurrence (ROR) score could improve breast cancer prognostication. Caveolin-1 (CAV1) is a marker of an active TME. CAV1 is a membrane protein involved in cell si
Externí odkaz:
https://doaj.org/article/97f3d582073e472a88a489644135df4a
Autor:
João Casanova, Ana G. da Costa, Ana Pestana Lopes, Ana Catarino, Mónica Nave, Ana Carla Sousa, Jorge Lima
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
BackgroundSince the seminal publication of the TCGA consortium in 2013, the molecular classification of endometrial cancer has been widely accepted as a new and powerful tool to better understand the natural history of this malignancy. Adoption of ro
Externí odkaz:
https://doaj.org/article/8d585cfa59b34a47a6dbffab123189d8
Autor:
Francesca Romana Di Pietro, Sofia Verkhovskaia, Rosa Falcone, Giulia Poti, Maria Luigia Carbone, Maria Francesca Morelli, Albina Rita Zappalà, Roberto Morese, Zorika Christiana Di Rocco, Gabriele Piesco, Paolo Chesi, Cristina Maria Failla, Paolo Marchetti, Federica De Galitiis
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundStage III surgically resected melanoma is a disease at high risk of recurrence. Immune checkpoint inhibitors (ICIs) and the target therapy with BRAF and MEK inhibitors significantly changed the outcome of patients with metastatic melanoma a
Externí odkaz:
https://doaj.org/article/4e3a503e397a44e9aa55f222bb49925b
Autor:
Abhishek Chauhan, Vinay Mohan Pathak, Monika Yadav, Ritu Chauhan, Neelesh Babu, Manish Chowdhary, Anuj Ranjan, Darin Mansor Mathkor, Shafiul Haque, Hardeep Singh Tuli, Seema Ramniwas, Vikas Yadav
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Gastrointestinal malignancies are one of the major worldwide health concerns. In the present review, we have assessed the plausible therapeutic implication of Ursolic Acid (UA) against gastrointestinal cancer. By modulating several signaling pathways
Externí odkaz:
https://doaj.org/article/15cad30e9ce24d21a45fc5d22c6d3861
Autor:
Mustafa Ozdogan, Eirini Papadopoulou, Vasiliki Metaxa-Mariatou, George Kapetsis, Angeliki Meintani, Chrysiida Florou-Chatzigiannidou, Akin Yildiz, Muharrem Okan Cakir, Onder Kirca, George Nasioulas
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Predictive biomarkers are necessary for the identification of immunotherapy-responsive patients. Tumor mutation burden (TMB), as determined by next-generation sequencing (NGS), and PD-L1 expression, as evaluated by Immunohistochemistry (IHC), are the
Externí odkaz:
https://doaj.org/article/e74dcadbd5e740dbb31fb48151687675