Zobrazeno 1 - 10
of 2 469
pro vyhledávání: '"molecular network"'
Autor:
Lakshmi N Sridhar
Publikováno v:
AIMS Bioengineering, Vol 11, Iss 2, Pp 266-280 (2024)
Molecular biological networks are highly nonlinear systems that exhibit limit point singularities. Bifurcation analysis and multiobjective nonlinear model predictive control (MNLMPC) of a molecular network problem represented by the Pettigrew model w
Externí odkaz:
https://doaj.org/article/15672e5693654bddad22baecc697e795
Publikováno v:
Microbiology Research, Vol 15, Iss 2, Pp 447-456 (2024)
Over the decades, the aquaculture sector has witnessed substantial growth, contributing significantly to the nation’s economy. However, the menace of CyanoHABs threatens the sustainability of fish farming. Considering the possible hazards linked to
Externí odkaz:
https://doaj.org/article/a6afa35b1e854acb9a157821dca6036a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The prediction of potential protein–protein interactions (PPIs) is a critical step in decoding diseases and understanding cellular mechanisms. Traditional biological experiments have identified plenty of potential PPIs in recent years, but
Externí odkaz:
https://doaj.org/article/87c22ecccafa4f7dbe68a01103186b17
Autor:
Dee Yu, Kaokao Zhu, Mu Li, Fei Zhang, Yuan Yang, Chunyun Lu, Shanmei Zhong, Cai Qin, Yanan Lan, Jipeng Yu, Jindong Ding Petersen, Junjun Jiang, Hao Liang, Li Ye, Bingyu Liang
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background HIV-1 CRF65_cpx strain carries drug-resistant mutations, which raises concerns about its potential for causing virologic failure. The CRF65_cpx ranks as the fourth most prevalent on Hainan Island, China. However, the origin and mo
Externí odkaz:
https://doaj.org/article/0ccccac890dd4e8dbed60f87400f8602
Autor:
Ke Hung Tsui, Chien-Liang Liu, Hsiu-Lien Yeh, Ming-Kun Liu, Chien-Hsiu Li, Wei-Hao Chen, Kuo-Ching Jiang, Han-Ru Li, Phan Vu Thuy Dung, Michael Hsiao, Wassim Abou-Kheir, Yen-Nien Liu
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110562- (2024)
Summary: The interaction between prostate cancer (PCa) cells and prostate stromal cells fosters an immunosuppressive tumor microenvironment (TME) that promotes tumor growth and immune evasion. However, the specific signaling pathways involved remain
Externí odkaz:
https://doaj.org/article/b2660cab58d940baabbe7a276815442f
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110371- (2024)
Summary: Ab initio computational reconstructions of protein-protein interaction (PPI) networks will provide invaluable insights into cellular systems, enabling the discovery of novel molecular interactions and elucidating biological mechanisms within
Externí odkaz:
https://doaj.org/article/37b37cb66f144cc782610e2d61e925b0
Autor:
Sarthak Sahoo, Soundharya Ramu, Madhumathy G. Nair, Maalavika Pillai, Beatriz P. San Juan, Heloisa Zaccaron Milioli, Susmita Mandal, Chandrakala M. Naidu, Apoorva D. Mavatkar, Harini Subramaniam, Arpita G. Neogi, Christine L. Chaffer, Jyothi S. Prabhu, Jason A. Somarelli, Mohit Kumar Jolly
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110116- (2024)
Summary: Intra-tumoral phenotypic heterogeneity promotes tumor relapse and therapeutic resistance and remains an unsolved clinical challenge. Decoding the interconnections among different biological axes of plasticity is crucial to understand the mol
Externí odkaz:
https://doaj.org/article/184f963418524796bef6f9437338f851
Autor:
Bing Guo, Lina Yang, Hengyang Li, Qi An, Yongli Liu, Jie Cheng, Fangjie Hou, Long Guo, Dan Zhang
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
ObjectiveEphedra, widely used in clinical practice as a medicinal herb, belongs to the genus Ephedra in the family Ephedraceae. However, the presence of numerous Ephedra varieties and variants requires differentiation for accurate identification.Meth
Externí odkaz:
https://doaj.org/article/4db6d67d335341efbb02256553e8202a
Autor:
Shan He, Matthew M. Gubin, Hind Rafei, Rafet Basar, Merve Dede, Xianli Jiang, Qingnan Liang, Yukun Tan, Kunhee Kim, Maura L. Gillison, Katayoun Rezvani, Weiyi Peng, Cara Haymaker, Sharia Hernandez, Luisa M. Solis, Vakul Mohanty, Ken Chen
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110096- (2024)
Summary: Recent developments in immunotherapy, including immune checkpoint blockade (ICB) and adoptive cell therapy (ACT), have encountered challenges such as immune-related adverse events and resistance, especially in solid tumors. To advance the fi
Externí odkaz:
https://doaj.org/article/857a54432adf43e68098a98661073bd8
Autor:
Hui Wang, Yashoda M. Hosakote, Paul J. Boor, Jun Yang, Yuanyi Zhang, Xiaoying Yu, Casey Gonzales, Corri B. Levine, Susan McLellan, Nicole Cloutier, Xuping Xie, Pei-Yong Shi, Ping Ren, Haitao Hu, Keer Sun, Lynn Soong, Jiaren Sun, Yuejin Liang
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110117- (2024)
Summary: Dysregulated host immune responses contribute to disease severity and worsened prognosis in COVID-19 infection and the underlying mechanisms are not fully understood. In this study, we observed that IL-33, a damage-associated molecular patte
Externí odkaz:
https://doaj.org/article/05478d599ee54e169c154b5090b33c58