Zobrazeno 1 - 10
of 323
pro vyhledávání: '"mohammed bouachrine"'
Autor:
Ayoub Khaldan, Soukaina Bouamrane, Reda El-Mernissi, Marwa Alaqarbeh, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi, Abdelouahid Sbai
Publikováno v:
Current Chemistry Letters, Vol 14, Iss 1, Pp 79-106 (2025)
Diabetes mellitus is a serious health disease that affects people all over the world. The number of persons identified with diabetes mellitus rises each year. α -Glucosidase is a digestive enzyme used to control diabetes mellitus. The searching for
Externí odkaz:
https://doaj.org/article/7e1957ce43db4f55bf6d7bfc1bbcabdb
Autor:
Mohamed Ouabane, Zouhir Dichane, Marwa Alaqarbeh, Radwan Alnajjar, Chakib Sekkate, Tahar Lakhlifi, Mohammed Bouachrine
Publikováno v:
Current Chemistry Letters, Vol 14, Iss 1, Pp 205-232 (2025)
While the number of AIDS-related deaths continues to rise, efforts have been made to transform the disease into a manageable chronic condition. HIV protease inhibitors have become central to combination therapy. As a result, these inhibitors have bec
Externí odkaz:
https://doaj.org/article/96a4690f3573486d93d70318c316166c
Publikováno v:
Current Chemistry Letters, Vol 14, Iss 1, Pp 183-192 (2025)
The mechanism and regioselectivity of 1,3-dipolar reaction of 2-azido-N-(4-diazenylphenyl) acetamide and an alkyne have been studied in gas phase and in DMSO using the B3LYP-GD3 functional and 6-31G(d,p) basis set. The reaction followed a one-step me
Externí odkaz:
https://doaj.org/article/fcf68174926c4e9993c347178e210a8a
Autor:
Khadija Zaki, Fatimazahra Fakir, Abdelouahid Sbai, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi
Publikováno v:
Current Chemistry Letters, Vol 13, Iss 3, Pp 451-466 (2024)
Protein IDO1 (indoleamine 2,3-dioxygenase) occupies a critical position in the regulation of the immune system and is involved in cancer progression and the development of immune diseases. Being a therapeutic target for such critical diseases, we aim
Externí odkaz:
https://doaj.org/article/76c6be4381ef4d0d9bf7273bcb778c57
Autor:
Said El Rhabori, Marwa Alaqarbeh, Abdellah El Aissouq, Mohammed Bouachrine, Samir Chtita, Fouad Khalil
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100455- (2024)
Breast cancer is the most frequent form of malignant tumor in women, and represents a major public health problem due to its high mortality rate. Although a multitude of therapeutic options exist for control of this disease, the emergence of resistan
Externí odkaz:
https://doaj.org/article/b392200b709247dbad17bf6f68b393e7
Autor:
Soukaina Bouamrane, Ayoub Khaldan, Marwa Alaqarbeh, Abdelouahid Sbai, Mohammed Aziz Ajana, Tahar Lakhlifi, Mohammed Bouachrine, Hamid Maghat
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100502- (2024)
Fungal infections are a growing public health problem worldwide. Despite the availability of several medicines, their efficacy is still constrained by fungal resistance. This research conducted the 2D/3D-QSAR analysis on twenty-nine triazole molecule
Externí odkaz:
https://doaj.org/article/ed52f1aba3dd48468596591a87199319
Autor:
Ayoub Khaldan, Soukaina Bouamrane, Reda El-mernissi, Mohamed Ouabane, Marwa Alaqarbeh, Hamid Maghat, Mohammed Aziz Ajana, Chakib Sekkat, Mohammed Bouachrine, Tahar Lakhlifi, Abdelouahid Sbai
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105656- (2024)
Diabetes mellitus is a chronic and non-infectious metabolic disorder caused by insufficient insulin secretion. This study investigated a set of thirty-one 4-amino-1,2,4-triazole derivatives, experimentally evaluated for their α-glucosidase activity
Externí odkaz:
https://doaj.org/article/bb0a9df2199f4b89a6c426610662e072
Autor:
Soukaina Bouamrane, Ayoub Khaldan, Marwa Alaqarbeh, Abdelouahid Sbai, Mohammed Aziz Ajana, Mohammed Bouachrine, Tahar Lakhlifi, Hamid Maghat
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105642- (2024)
Fungal infections profoundly affect human health, causing a substantial number of infections and millions of fatalities annually on a global scale. The identification of new drugs targeting this infection is a challenge that is not yet complete. Natu
Externí odkaz:
https://doaj.org/article/e1a1625d98d74b1fa1f7ae5bc2bd83f7
Autor:
Imane Yamari, Oussama Abchir, Farhan Siddique, Hanane Zaki, Abdelkbir Errougui, Mohammed Talbi, Mohammed Bouachrine, M'hammed ElKouali, Samir Chtita
Publikováno v:
Scientific African, Vol 23, Iss , Pp e01986- (2024)
Lippia Alba, a plant commonly utilized in traditional folk medicine, particularly in Brazil, is renowned for its essential oil possessing anti-inflammatory, antibacterial, anesthetic, and antiviral properties. In this study, we conducted molecular an
Externí odkaz:
https://doaj.org/article/c8ad5e06319241cd98ca27c59b567810
Autor:
Esslali Soukaina, Liman Wissal, Koubi Yassine, El Allali Achraf, Farhate Guenoun, Mohammed Bouachrine
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 2, Pp 105584- (2024)
The 3CL protease plays a crucial role in the life cycle of SARS-CoV. This protease is considered an important antiviral target. In the present work, the 3D-QSAR study was performed on a set composed of twenty-six dipeptide SARS-CoV 3CLpro inhibitors
Externí odkaz:
https://doaj.org/article/5da58091681146a685c9ab68ab6533a6