Zobrazeno 1 - 2
of 2
pro vyhledávání: '"models zebrafish"'
Autor:
Dzung, Andreas, Saltari, Annalisa, Tiso, Natascia, Lyck, Ruth, Dummer, Reinhard, Levesque, Mitchell P
Publikováno v:
Dzung, Andreas; Saltari, Annalisa; Tiso, Natascia; Lyck, Ruth; Dummer, Reinhard; Levesque, Mitchell P (2022). STK11 Prevents Invasion Through STAT3/5 and FAK Repression in Cutaneous Melanoma. Journal of investigative dermatology, 142(4), 1171-1182.e10. Elsevier 10.1016/j.jid.2021.09.035
The serine/threonine kinase 11 (STK11/LKB1) is a tumor suppressor involved in metabolism and cell motility. In BRAFV600E melanoma, STK11 is inactivated by ERK and RSK, preventing it from binding and activating AMPK and promoting melanoma cell prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415598b98bcf640375faf748019e79a3
http://hdl.handle.net/11577/3405054
http://hdl.handle.net/11577/3405054
Autor:
Carvalho S; Research and Development Unit, Department of Human Genetics, INSA.; Faculty of Pharmacy, University of Coimbra.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., Moreira L; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., Santos JI; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals.; Biology department, Faculty of Sciences, University of Porto., Gaspar P; Newborn Screening, Metabolism and Genetics Unit, Department of Human Genetics, INSA., Gonçalves M; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals.; Inov4Agro, University of Trás-os-Montes and Alto Douro, CITAB, UTAD., Matos L; University of Porto Center for the Study of Animal Science, CECA-ICETA Porto Portugal.; Research and Development Unit, Department of Human Genetics, INSA.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., David H; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals.; Biology department, Faculty of Sciences, University of Porto., Encarnação M; Research and Development Unit, Department of Human Genetics.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., Ribeiro D; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals.; Newborn Screening, Metabolism and Genetics Unit, Department of Human Genetics, INSA., Duarte AJ; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., Amaral O; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., Rocha H; Newborn Screening, Metabolism and Genetics Unit, Department of Human Genetics, INSA., Diogo L; Centro de Referência de Doenças Hereditárias do Metabolismo, CHUC., Ferreira S; Centro de Referência de Doenças Hereditárias do Metabolismo, CHUC., Santos C; Centro de Referência de Doenças Hereditárias do Metabolismo, CHUC., Martins E; Centro Hospitalar Universitário do Porto, Hospital de Santo António, CHUdSA., Neuparth T; Endocrine Disrupters and Emerging Contaminants Group, CIMAR/CIIMAR, LA - Interdisciplinary Centre of Marine and Environmental Research., Soares J; Endocrine Disrupters and Emerging Contaminants Group, CIMAR/CIIMAR, LA - Interdisciplinary Centre of Marine and Environmental Research., Ribeiro M; Endocrine Disrupters and Emerging Contaminants Group, CIMAR/CIIMAR, LA - Interdisciplinary Centre of Marine and Environmental Research., Ribeiro Pinho B; Department of Drug Sciences, Pharmacology Lab, University of Porto, UCIBIO-REQUIMTE.; Department of Drug Sciences, Pharmacology Lab, University of Porto i4HB., Oliveira N; Department of Drug Sciences, Pharmacology Lab, University of Porto, UCIBIO-REQUIMTE.; Department of Drug Sciences, Pharmacology Lab, University of Porto i4HB., Ascenção Oliveira JM; Department of Drug Sciences, Pharmacology Lab, University of Porto, UCIBIO-REQUIMTE.; Department of Drug Sciences, Pharmacology Lab, University of Porto i4HB., Prata MJ; Biology department, Faculty of Sciences, University of Porto.; 13i3S - Health research and innovation institute, University of Porto., Santos M; Biology department, Faculty of Sciences, University of Porto.; Endocrine Disrupters and Emerging Contaminants Group, CIMAR/CIIMAR, LA - Interdisciplinary Centre of Marine and Environmental Research., Alves S; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals., Coutinho MF; Research and Development Unit, Department of Human Genetics, INSA.; Center for the Study of Animal Science, CECA-ICETA, University of Porto.; Associate Laboratory for Animal and Veterinary Sciences, AL4 Animals.
Publikováno v:
Endocrine, metabolic & immune disorders drug targets [Endocr Metab Immune Disord Drug Targets] 2023 Nov 02. Date of Electronic Publication: 2023 Nov 02.
