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Akademický článek

MOB kinase activator 1A acts as an oncogene by targeting PI3K/AKT/mTOR in ovarian cancer

Autor: Jian Lei, Jing-Ying Xu, Min Hu, San-Gang Wu, Juan Zhou

Publikováno v: Discover Oncology, Vol 14, Iss 1, Pp 1-18 (2023)

Abstract Background To illuminate the precise roles of MOB Kinase Activator 1 A (MOB1A) in the development of ovarian cancer (OC). Methods MOB1A expression and clinical data of OC were obtained from the public database on gene expression and proteomi

Externí odkaz: https://doaj.org/article/5aea474b2f2f4713a74b386fb89a00ff

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Akademický článek

Analysis of methylation and expression profile of MOB1A in blood, saliva, and tissue of patients with oral squamous cell carcinoma (OSCC) and precancerous patients

Autor: Hanieh Soleimani, Mohammad Rigi Ladez, Dor Mohammad Kordi-Tamandani

Publikováno v: Journal of Epigenetics, Vol 3, Iss 2, Pp 39-44 (2022)

Background: Oral squamous cell carcinoma (OSCC) is considered the most common type of oral cavity malignancy worldwide. OSCC accounts for more than 90% of all oral neoplasms. This cancer affects the lips, palate, and tongue and the average survival r

Externí odkaz: https://doaj.org/article/232c08641e574c2eacc56708408b6ebf

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Akademický článek

Analysis of Expression Profiles of GLI3A, LATS2 and MOB1A genes in Patients with Congenital hypothyroidism

Autor: Sepideh Eisazaei, Maryam Nakhaee-Moghadam, Dor-Mohammad Kordi Tamandani

Publikováno v: Journal of Epigenetics, Vol 3, Iss 1, Pp 21-26 (2022)

In recent years, congenital hypothyroidism (CH) has been reported as the most prevalent endocrine disorder and most common cause of preventable mental retardation in many parts of the world, especially in Asia. Delays in early diagnosis and treatment

Externí odkaz: https://doaj.org/article/6dc10ff7029e452db183ab9f124e1966

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Akademický článek

Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling

Autor: Xiangrong Cui, Huancheng Su, Jiaolin Yang, Xueqing Wu, Kai Huo, Xuan Jing, Sanyuan Zhang

Publikováno v: Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-14 (2022)

Abstract Background MTHFD2 is a folate-coupled metabolic enzyme, which has been proved to participant in the metabolic reprogramming and tumor cell-sustaining proliferative capacity. However, the function of MTHFD2 in the development of ovarian cance

Externí odkaz: https://doaj.org/article/e515dc5de33c4c96a99e28acd07d7402

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Akademický článek

Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression

Autor: Lingjiao Meng, Sheng Chang, Yang Sang, Pingan Ding, Liuxin Wang, Xixi Nan, Ruiyu Xu, Fei Liu, Lina Gu, Yang Zheng, Ziyi Li, Meixiang Sang

Publikováno v: Breast Cancer Research, Vol 24, Iss 1, Pp 1-13 (2022)

Abstract Background A growing body of evidence indicates that abnormal expression of circular RNAs (circRNAs) plays a crucial role by acting as molecular sponges of microRNAs (miRNAs) in various diseases, including cancer. In this study, we explored

Externí odkaz: https://doaj.org/article/06f793e28cb24b9683a0f4acdde803db

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Akademický článek

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Akademický článek

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Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling

Autor: Sanyuan Zhang, Jiaolin Yang, Xuan Jing, Xueqing Wu, Xiangrong Cui, Kai Huo, Huancheng Su

Publikováno v: Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-14 (2022)

Background MTHFD2 is a folate-coupled metabolic enzyme, which has been proved to participant in the metabolic reprogramming and tumor cell-sustaining proliferative capacity. However, the function of MTHFD2 in the development of ovarian cancer and its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1760b087d10fbe068deba15d3ffe6641
https://pubmed.ncbi.nlm.nih.gov/35135596

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Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression

Autor: Lingjiao Meng, Sheng Chang, Yang Sang, Pingan Ding, Liuxin Wang, Xixi Nan, Ruiyu Xu, Fei Liu, Lina Gu, Yang Zheng, Ziyi Li, Meixiang Sang

Publikováno v: Breast Cancer Research : BCR
Breast Cancer Research, Vol 24, Iss 1, Pp 1-13 (2022)

Background A growing body of evidence indicates that abnormal expression of circular RNAs (circRNAs) plays a crucial role by acting as molecular sponges of microRNAs (miRNAs) in various diseases, including cancer. In this study, we explored whether c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923aa89ca4a63d7ac78a9ec9597cf655
https://pubmed.ncbi.nlm.nih.gov/34983617

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