Zobrazeno 1 - 10
of 608
pro vyhledávání: '"mixed phenotype acute leukemia"'
Autor:
Masanori Aoki, Maho Ishikawa, Tsugumi Sato, Yoshitada Taji, Hidekazu Kayano, Naoki Takahashi, Yasuhiro Ebihara
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 855-858 (2024)
Abstract A 26‐year‐old man was diagnosed with B/T‐type mixed‐phenotype acute leukemia (MPAL‐B/T) based on blasts being positive for CD19, cytoplasmic CD3, and cyCD79a, but negative for myeloperoxidase. Acute lymphoblastic leukemia‐based c
Externí odkaz:
https://doaj.org/article/3bb2b0f9e4844f609515486ecc341c62
Autor:
Yusuke Takada, Shuhei Kurosawa, Toshimitsu Ueki, Yuho Najima, Satoshi Wakita, Hiroki Yamaguchi, Takako Yokota, Masaki Hibi, Ayumi Hirahara, Tsutomu Yoshida, So Okubo, Moe Masuda, Hitomi Nakayama, Aki Sakurai, Chisako Ito, Yoshinobu Aisa, Tomonori Nakazato
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 802-809 (2024)
Abstract Mixed‐phenotype acute leukemia (MPAL) with FLT3‐TKD mutations is a rare and challenging subtype of leukemia. Effective management strategies are crucial for improving patient outcomes. A 31‐year‐old man with FLT3‐TKD‐mutated MPAL
Externí odkaz:
https://doaj.org/article/9e043a80005145d6a962d5851eeb9dd1
Autor:
Khalil Khashei Varnamkhasti, Samire Khashei Varnamkhasti, Atefeh Shahrouzian, Masoomeh Rahimzadeh, Leila Naeimi, Behrouz Naeimi, Sirous Naeimi
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background The apparent lack of additional missense mutations data on mixed-phenotype leukemia is noteworthy. Single amino acid substitution by these non-synonymous single nucleotide variations can be related to many pathological conditions
Externí odkaz:
https://doaj.org/article/b708647b936444c786cd88b3242dbe1f
Autor:
Ji-nuo Wang, Bangcheng Ye, Fei Cheng, Li Yang, Yongxian Hu, Gaofeng Zheng, Zhen Cai, Jian Yu, Wenjun Wu
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Introduction: PICALM-MLLT10, formerly CALM-AF10, is a rarely reported fusion gene in hematological malignancies, especially in Asian people.Case presentations: Six patients with PICALM-MALLT10 fusion gene were identified at the First Affiliated Hospi
Externí odkaz:
https://doaj.org/article/f90accf898974e94a33f788713aa019f
Autor:
Kongfei Li, Yuxiao Wang, Renzhi Pei, Ying Lu, Junjie Cao, Xianxu Zhuang, Jiaying Lian, Bibo Zhang
Publikováno v:
Turkish Journal of Hematology, Vol 41, Iss 3, Pp 202-204 (2024)
Externí odkaz:
https://doaj.org/article/e70547399bb646d2a5a6c8a52a5ae63f
Autor:
Michèle Hoffmann, Yara Banz, Jörg Halter, Jacqueline Schoumans, Joëlle Tchinda, Ulrike Bacher, Thomas Pabst
Publikováno v:
Current Oncology, Vol 31, Iss 4, Pp 2067-2075 (2024)
Donor cell leukemia (DCL) is a rare complication after allogeneic hematopoietic stem cell transplantation (HSCT) accounting for 0.1% of relapses and presenting as secondary leukemia of donor origin. Distinct in phenotype and cytogenetics from the ori
Externí odkaz:
https://doaj.org/article/b7cce01b312e4f65b8657380b2efa76d
Autor:
Magdalena Karasek, Anna Armatys, Marek Skarupski, Łukasz Bołkun, Katarzyna Budziszewska, Joanna Drozd-Sokołowska, Ewa Zarzycka, Patrycja Mensah-Glanowska, Małgorzata Gajewska, Janusz Hałka, Agnieszka Kopacz, Witold Prejzer, Olga Chyrko, Tomasz Wróbel, Agnieszka Wierzbowska, Marta Sobas
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMixed-phenotype acute leukemia (MPAL) is a rare disease with poor prognosis. So far, no standard approach has been established as the “know-how” of MPAL is based only on retrospective analyses performed on small groups of patients.Mat
Externí odkaz:
https://doaj.org/article/6c1095aeb39d46c9b0c73d98b8066d54
Autor:
Hope L. Mumme, Sunil S. Raikar, Swati S. Bhasin, Beena E. Thomas, Taylor Lawrence, Elizabeth P. Weinzierl, Yakun Pang, Deborah DeRyckere, Chuck Gawad, Daniel S. Wechsler, Christopher C. Porter, Sharon M. Castellino, Douglas K. Graham, Manoj Bhasin
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features, is difficult to diagnose and treat. A better characterization of MPAL is essential to unde
Externí odkaz:
https://doaj.org/article/27b0d44d90b644919eac2539e49cde72
Autor:
Mahsa Khanlari, Lu Wang, Christine Y Bolen, Felipe Sebastian Bautista Otanez, Larissa V. Furtado, Laura Key, Lisa Irwin, Wei Wang, Jeffery M. Klco
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 765-769 (2023)
Abstract Herein, we present a rare case of acute myeloid leukemia (AML) with CBFA2T3‐rearrangement and the expression of megakaryocytic and lymphoid markers, highlighting the need for a high suspicion index in differential diagnosis and applying ad
Externí odkaz:
https://doaj.org/article/91c613b356e94af3a6b2641c91b5245d
Autor:
Ruifang Zheng, Franklin Fuda, Jeffrey R. Gagan, Olga K. Weinberg, Prasad Koduru, Miguel Cantu, Kathleen Ludwig, Jamie M. Truscott, Robert Collins, Stephen Chung, Yazan F. Madanat, Weina Chen
Publikováno v:
Leukemia Research Reports, Vol 21, Iss , Pp 100410- (2024)
B/T mixed phenotype acute leukemia (MPAL) is a rare aggressive leukemia. Three cases of B/T MPAL were identified with comprehensive immunophenotypic, cytogenetic, and molecular studies. T-lineage predominant B/T MPAL shares a genetic signature with T
Externí odkaz:
https://doaj.org/article/29321a2d531d4336987fdcd870ed2b8c