Zobrazeno 1 - 10
of 1 678
pro vyhledávání: '"mitochondrial targeting"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 12975-12998 (2024)
Lili Zhou,1 Yang Du,2 Yating Shang,1 Debiao Xiang,3,* Xinhua Xia1,* 1School of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, People’s Republic of China; 2The Second Affiliated Hospital of Hunan University of Chinese Medi
Externí odkaz:
https://doaj.org/article/3624fab45f6e4e7181d5d43710e8864a
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 7997-8014 (2024)
Yan Wang,1,2,* Fengmei Li,1,2,* Shanshan Wei,1,2,* Wenqun Li,1,2 Junyong Wu,1,2 Shengnan Li,1,2 Xiongbin Hu,1,2 Tiantian Tang,1,2 Xinyi Liu1,2 1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, Peopl
Externí odkaz:
https://doaj.org/article/1c6399d5a59243128c8dc83a5b0f06f4
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101282- (2024)
As the most aggressive and metastatic subtype of breast cancer, clinical demands of triple negative breast cancer (TNBC) have far not been met. Heat shock protein 60 (HSP60) is over expressed in tumor cells and impair the efficacy of photothermal the
Externí odkaz:
https://doaj.org/article/968e732d2eee4f16b451916a304a2584
Publikováno v:
In International Journal of Biological Macromolecules January 2025 285
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In recent decades, nanotechnology has significantly advanced drug delivery systems, particularly in targeting subcellular organelles, thus opening new avenues for disease treatment. Mitochondria, critical for cellular energy and health, when dysfunct
Externí odkaz:
https://doaj.org/article/b5ca6c805f114c1f8214fa69e4436502
Autor:
Meng, Yiling a, Wen, Tao a, ⁎⁎, Liu, Xuanxin a, Yang, Aiyun b, Meng, Jie a, Liu, Jian a, Wang, Jianhua b, Xu, Haiyan a, ⁎
Publikováno v:
In Materials Today Bio December 2024 29
Autor:
Kang, Lin a, Chen, Liqing b, Wang, Qiming b, Jin, Mingji b, Huang, Wei b, Gao, Zhonggao b, ⁎, Cui, Wenxiang c, ⁎⁎
Publikováno v:
In Journal of Drug Delivery Science and Technology March 2025 105
Autor:
Yong Mei, Xiaohua Qin, Zhenyu Yang, Shiyao Song, Xiaoting Liu, Chong Wu, Jieying Qian, Xiaowan Huang, Yunjiao Zhang, Weiling He
Publikováno v:
Bioactive Materials, Vol 32, Iss , Pp 277-291 (2024)
KRAS-TP53 co-mutation is strongly associated with poor prognosis and high malignancy in gastrointestinal cancers. Therefore, a novel approach to oncotherapy may lie in combination therapy targeting both KRAS and TP53. Herein, we present a novel self-
Externí odkaz:
https://doaj.org/article/cc74cdc98aaf4db28fccb096daf269d6
Autor:
Chenyu Wu, Ximiao Chen, Xiaoying Zhao, Yu Chen, Hao Zhou, Yuxin Deng, Chenchao Li, Yang Huang, Weiyang Gao, Di Zhang, Hongwei Ouyang, Xiaolei Zhang
Publikováno v:
Materials & Design, Vol 242, Iss , Pp 112972- (2024)
Spinal cord injury (SCI) is a severe central nerve diseases which lacks effective of treatment. Oxidative stress is a major pathological factor for SCI. It may induce mitochondrial damage, which further lead to ferroptosis and apoptosis in neural cel
Externí odkaz:
https://doaj.org/article/3e9127c741624984a12651a074487d2d
Nanomotor-based H2S donor with mitochondrial targeting function for treatment of Parkinson's disease
Autor:
Zinan Zhao, Lin Chen, Chunhao Yang, Wenyan Guo, Yali Huang, Wenjing Wang, Mimi Wan, Chun Mao, Jian Shen
Publikováno v:
Bioactive Materials, Vol 31, Iss , Pp 578-589 (2024)
Reduction of endogenous hydrogen sulfide (H2S) is considered to have an important impact on the progress of Parkinson's disease (PD), thus exogenous H2S supplementation is expected to become one of the key means to treat PD. However, at present, it i
Externí odkaz:
https://doaj.org/article/b187542044e6418d85fdcdcce209816d