Zobrazeno 1 - 10
of 118
pro vyhledávání: '"mitochondrial motility"'
Publikováno v:
Cells, Vol 12, Iss 9, p 1287 (2023)
Mitochondrial bioenergetics and dynamics (alterations in morphology and motility of mitochondria) play critical roles in neuronal reactions to varying energy requirements in health and disease. In Alzheimer’s disease (AD), mitochondria undergo exce
Externí odkaz:
https://doaj.org/article/a6e1559c85964d62b6742e72b0f8009e
Akademický článek
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Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 410-418 (2019)
Mitochondria are crucial organelles for neurophysiology and brain mitochondrial defects constitute a characteristic of Alzheimer's disease (AD). Impaired axonal mitochondrial traffic, especially the anterograde axonal mitochondrial transport is a pro
Externí odkaz:
https://doaj.org/article/54de96da8a91416a9f62799f8c351ffe
Publikováno v:
Cells, Vol 11, Iss 10, p 1710 (2022)
Recently, we have shown that the physiological roles of a multifunctional protein fructose 1,6-bisphosphatase 2 (FBP2, also called muscle FBP) depend on the oligomeric state of the protein. Here, we present several lines of evidence that in HL-1 card
Externí odkaz:
https://doaj.org/article/9c784cca1aa04da7bef691eb91a58224
Autor:
Ashley E. Gonzalez, Xinnan Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Valosin-containing protein (VCP), also called p97, is an evolutionarily conserved and ubiquitously expressed ATPase with diverse cellular functions. Dominant mutations in VCP are found in a late-onset multisystem degenerative proteinopathy. The neuro
Externí odkaz:
https://doaj.org/article/514d9f2754cd4d2f9783cefcd5835acd
Autor:
Kai Yang, Zhixi Chen, Juanjuan Gao, Weimei Shi, Linfu Li, Shan Jiang, Haibo Hu, Zhiping Liu, Daohua Xu, Longhuo Wu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1445-1459 (2017)
Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, has been reported to show essential roles in molecular pathophysiology of many diseases. Mitochondrion is a dynamic organelle for producing cellular energy and determining cel
Externí odkaz:
https://doaj.org/article/339c88e97c04441e89f5f39f2aafe53c
Akademický článek
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Publikováno v:
Cells; Volume 11; Issue 10; Pages: 1710
Recently, we have shown that the physiological roles of a multifunctional protein fructose 1,6-bisphosphatase 2 (FBP2, also called muscle FBP) depend on the oligomeric state of the protein. Here, we present several lines of evidence that in HL-1 card
Autor:
Infante-Duarte, Bimala Malla, Agustin Liotta, Helena Bros, Rebecca Ulshöfer, Friedemann Paul, Anja E. Hauser, Raluca Niesner, Carmen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1538
Teriflunomide (TFN) limits relapses in relapsing–remitting multiple sclerosis (RRMS) by reducing lymphocytic proliferation through the inhibition of the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) and the subsequent modulation of de n
Autor:
Malla, Bimala, Liotta, Agustin, Bros, Helena, Ulshöfer, Rebecca, Paul, Friedemann, Hauser, Anja E., Niesner, Raluca, Infante-Duarte, Carmen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1538, p 1538 (2022)
Teriflunomide (TFN) limits relapses in relapsing-remitting multiple sclerosis (RRMS) by reducing lymphocytic proliferation through the inhibition of the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) and the subsequent modulation of de nov