Výsledky vyhledávání - "mitochondrial inhibition"

Akademický článek

Selectively down-regulated PD-L1 by albumin-phenformin nanoparticles mediated mitochondrial dysfunction to stimulate tumor-specific immunological response for enhanced mild-temperature photothermal efficacy

Autor: Zaigang Zhou, Ning Jiang, Jiashe Chen, Chunjuan Zheng, Yuanyuan Guo, Ruirong Ye, Ruogu Qi, Jianliang Shen

Publikováno v: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-22 (2021)

Highlights Over-expression of PD-L1 after mild-photothermal therapy significantly limited its efficacy. Phenformin could effectively downregulate PD-L1 expression and inhibit tumor metastasis through AMPK activation. Hydrogen peroxide responsive mang

Externí odkaz: https://doaj.org/article/c48cc67a29084172b104624fff504bb1

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Akademický článek

Activities of Endochin-Like Quinolones Against in vitro Cultured Besnoitia besnoiti Tachyzoites

Autor: Naja Eberhard, Vreni Balmer, Joachim Müller, Norbert Müller, Rolf Winter, Soviti Pou, Aaron Nilsen, Mike Riscoe, Samuel Francisco, Alexandre Leitao, J. Stone Doggett, Andrew Hemphill

Publikováno v: Frontiers in Veterinary Science, Vol 7 (2020)

Endochin-like quinolones (ELQs) potently inhibit the proliferation of Plasmodium, Toxoplasma, Neospora, and Babesia by targeting the cytochrome b Qo and Qi sites and interfering with oxidative phosphorylation and pyrimidine biosynthesis. The activiti

Externí odkaz: https://doaj.org/article/3018e9a1963f4eb2a00b256113e60aed

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Akademický článek

Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Autor: Balaraman Kalyanaraman, Gang Cheng, Micael Hardy, Olivier Ouari, Brian Bennett, Jacek Zielonka

Publikováno v: Redox Biology, Vol 15, Iss C, Pp 347-362 (2018)

Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the most

Externí odkaz: https://doaj.org/article/beeb187ade74409ab4180080809dc0ed

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Effect of Carbon Monoxide (CO) Poisoning, Toxic Effects of CO Poisoning, Symptoms Of Co Poisoning, Influence Of Co On Different Systems of the Body, Pathogenesis of Co Poisoning, Diagnosis of CO Poisoning, Prevention of CO Poisoning and Treatment For CO Poisoning

Autor: Pavan Eswar Reddy. K, Pavan Kumar. K, Muralinath. E, Mohan Naidu. K, Guru Prasad. M, Amrutham Sandeep, Sravani Pragna. K

Carbon monoxide (CO) is treated as silent killer. CO is a dangerous gas that leads to the occurrence of death. The CO is available from coal, gasoline, natural gas, propane as well as wood. The source of CO is defective furnaces, water heater, gas ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b3d80fcd372b1fe024b7f7cc84960b

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Akademický článek

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Akademický článek

Fas-associated factor 1 and Parkinson's disease

Autor: Ranjita Betarbet, Leah R. Anderson, Marla Gearing, Tiffany R. Hodges, Jason J. Fritz, James J. Lah, Allan I. Levey

Publikováno v: Neurobiology of Disease, Vol 31, Iss 3, Pp 309-315 (2008)

Fas-associated factor 1 or FAF1 is a Fas-binding protein implicated in apoptosis. FAF1 is the product of a gene at PARK 10 locus on chromosome 1p32, a locus associated with late-onset PD [Hicks, A.A., Petursson, H., Jonsson, T., Stefansson, H., Johan

Externí odkaz: https://doaj.org/article/7c9fcdd98d094fa0a18df4435acfc15c

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Akademický článek

Decreasing Glycolysis Increases Sensitivity to Mitochondrial Inhibition in Primary Cultures of Renal Proximal Tubule Cells

Publikováno v: In Vitro Cellular & Developmental Biology. Animal, 1994 Jan 01. 30A(1), 30-34.

Externí odkaz: https://www.jstor.org/stable/4294180

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Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Autor: Olivier Ouari, Balaraman Kalyanaraman, Gang Cheng, Micael Hardy, Brian Bennett, Jacek Zielonka

Publikováno v: Redox Biology, Vol 15, Iss C, Pp 347-362 (2018)
Redox Biology
Redox Biology, 2018, 15, pp.347--362. ⟨10.1016/j.redox.2017.12.012⟩

WOS:000436226600032; Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98b676fd28174fc07550280dd0708d7
http://www.sciencedirect.com/science/article/pii/S221323171730931X

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