Zobrazeno 1 - 10
of 8 025
pro vyhledávání: '"mitochondrial fission"'
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background During the aging process, the number and functional activity of endothelial progenitor cells (EPCs) are impaired, leading to the unsatisfactory efficacy of transplantation. Previous studies demonstrated that Yiqihuoxue decoction (
Externí odkaz:
https://doaj.org/article/7d9c24e8c3b24c5f99fd1d45089135f6
Autor:
Jiejie Zhang, Shan Wang, Haitao Zhang, Xiaotong Yang, Xin Ren, Lei Wang, Yihan Yang, Yi Yang, Ya Wen
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-19 (2024)
Abstract The aberrant acetylation of mitochondrial proteins is involved in the pathogenesis of multiple diseases including neurodegenerative diseases and cerebral ischemic injury. Previous studies have shown that depletion of mitochondrial NAD+, whic
Externí odkaz:
https://doaj.org/article/51b25f8766ba48aaa422fc9672ae9deb
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-31 (2024)
Abstract Heterocyclic compounds play a crucial role in the drug discovery process and development due to their significant presence and importance. Here, we report a comprehensive analysis of α-aminophosphonates containing pyridine (3a–g), prepare
Externí odkaz:
https://doaj.org/article/10381ea1e6ae42bc9bc280f33d997cc2
Autor:
Zhi-Yan Liu, Li-Chan Lin, Zhen-Yu Liu, Kai Song, Bin Tu, He Sun, Yang Zhou, Sui Mao, Ye Zhang, Rui Li, Jing-Jing Yang, Jian-Yuan Zhao, Hui Tao
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-20 (2024)
Abstract Background N 6-methyladenosine (m6A) modification of messenger RNA (mRNA) is crucial for liquid-liquid phase separation in mammals. Increasing evidence indicates that liquid-liquid phase separation in proteins and RNAs affects diabetic cardi
Externí odkaz:
https://doaj.org/article/60f532a8b20542a6be55398296b0facd
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 39, Iss 2, Pp 67-80 (2024)
Background: Post-ovulatory aging (POA) of oocytes is related to a decrease in the quality and quantity of oocytes caused by aging. Previous studies on the characteristics of POA have investigated injury to early embryonic developmental ability, but n
Externí odkaz:
https://doaj.org/article/095d52b1f4504633b238675590e8c088
Autor:
Yuki Hanada, Risa Maeda, Takaya Ishihara, Masaki Nakahashi, Yuichi Matsushima, Emi Ogasawara, Toshihiko Oka, Naotada Ishihara
Publikováno v:
Pharmacological Research, Vol 209, Iss , Pp 107414- (2024)
Mitochondrial morphology and function change dynamically in response to intracellular signaling and the surrounding environment. The mitochondrial fission factor Mff, which localizes to the outer mitochondrial membrane, mediates not only mitochondria
Externí odkaz:
https://doaj.org/article/442d9e543406442290c563f69102265a
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101266- (2024)
Abnormal mitochondrial dynamics can lead to seizures, and improved mitochondrial dynamics can alleviate seizures. Vacuolar protein sorting 13D (VPS13D) is closely associated with regulating mitochondrial homeostasis and autophagy. However, further in
Externí odkaz:
https://doaj.org/article/65579879e6764d2895ff3a9b3fe9249b
Autor:
Yu Zhu, Lei Kuang, Yue Wu, Haoyue Deng, Han She, Yuanqun Zhou, Jie Zhang, Liangming Liu, Tao Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/39be276dba444cdb86ee53412ab49633
Autor:
Gongyi Xiao, Xiangwei Li, Huiping Yang, Ruobin Zhang, Junlan Huang, Yu Tian, Mao Nie, Xianding Sun
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background The larval zebrafish tail fin can completely regenerate in 3 days post amputation. mTOR, the main regulator of cell growth and metabolism, plays an essential role in regeneration. Lots of studies have documented the role of mTOR i
Externí odkaz:
https://doaj.org/article/6163a73a05c44372b10dfe6a43deda75
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung diseases, which mainly existed in middle-aged and elderly people. The accumulation of reactive oxygen species (ROS) is a common characteristic of IPF.
Externí odkaz:
https://doaj.org/article/2f47a8f47fe7410f96bd820fe5cdfee2