Zobrazeno 1 - 10
of 412
pro vyhledávání: '"mitochondrial energy metabolism"'
Autor:
Akiyuki Nishimura, Tomohiro Tanaka, Kakeru Shimoda, Tomoaki Ida, Shota Sasaki, Keitaro Umezawa, Hiromi Imamura, Yasuteru Urano, Fumito Ichinose, Toshiro Kaneko, Takaaki Akaike, Motohiro Nishida
Publikováno v:
Redox Biology, Vol 79, Iss , Pp 103445- (2025)
Ischemic heart disease is the main global cause of death in the world. Abnormal sulfide catabolism, especially hydrogen sulfide accumulation, impedes mitochondrial respiration and worsens the prognosis after ischemic insults, but the substantial ther
Externí odkaz:
https://doaj.org/article/331751f6da0e4dc194cde4085037029a
Autor:
Liangliang Bai, Linping Wu, Changsheng Zhang, Zhiwen Liu, Liang Ma, Jing Ni, Dezhen He, Mingxuan Zhu, Shaoyong Peng, Xiaoxia Liu, Huichuan Yu, Yuhe Lei, Yanxin Luo, Yu Zhang, Xiaolin Wang, Gang Wei, Yingjie Li
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101056- (2024)
Diabetic foot ulcer (DFU) is a highly morbid complication in patients with diabetes mellitus, necessitating the development of innovative pharmaceuticals to address unmet medical needs. Sodium ion (Na+) is a well-established mediator for membrane pot
Externí odkaz:
https://doaj.org/article/5371544bd83341798ecac0caf1ff0738
Autor:
Kaixin Guo, Yan Lu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
AimsThe main objective of this study was to investigate the role and mechanism of acupuncture on anti-nerve injury in the acute phase by regulating mitochondrial energy metabolism via monophosphate-activated protein kinase (AMPK)/peroxisome prolifera
Externí odkaz:
https://doaj.org/article/b4d735807cc5425e91a353a6e8ce3771
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Pancreatic adenocarcinoma (PAAD) is a highly malignant gastrointestinal tumor and is associated with an unfavorable prognosis worldwide. Considering the effect of mitochondrial metabolism on the prognosis of pancreatic cancer has rarely b
Externí odkaz:
https://doaj.org/article/f1f77ab2e2044bd0a7dd7a3a99a935c0
Autor:
Akira Nishimura, Sunghyeon Yoon, Tetsuro Matsunaga, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Jun Yoshitake, Yuka Unno, Uladzimir Barayeu, Tsuyoshi Takata, Hiroshi Takagi, Hozumi Motohashi, Albert van der Vliet, Takaaki Akaike
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 103018- (2024)
Supersulfides, which are defined as sulfur species with catenated sulfur atoms, are increasingly being investigated in biology. We recently identified pyridoxal phosphate (PLP)-dependent biosynthesis of cysteine persulfide (CysSSH) and related supers
Externí odkaz:
https://doaj.org/article/7f0b088435fd49b3b0b93a146c4667df
Autor:
Anna Atlante, Daniela Valenti
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 5, Pp 4451-4479 (2023)
Mitochondria have made a long evolutionary path from ancient bacteria immigrants within the eukaryotic cell to become key players for the cell, assuming crucial multitasking skills critical for human health and disease. Traditionally identified as th
Externí odkaz:
https://doaj.org/article/68a0e5c41afa4dba8a1a61bf9fda6e6b
Publikováno v:
Metabolites, Vol 14, Iss 7, p 369 (2024)
Alzheimer’s disease (AD) is a neurodegenerative disease. Mitochondrial energy metabolism and p70 ribosomal protein S6 kinase (p70S6K) play significant roles in AD pathology. However, the potential relationship between them is unclear. In this study
Externí odkaz:
https://doaj.org/article/3d9265d833e14f51803d0657bfccd303
Autor:
Jiaxiang Luo, Chen Ren, Tingting Zhu, Chen Guo, Shichao Xie, Yingying Zhang, Zheng Yang, Wenli Zhao, Xiangsheng Zhang, Jingjing Lu, Lefei Jiao, Qicun Zhou, Douglas R. Tocher, Min Jin
Publikováno v:
Animal Nutrition, Vol 12, Iss , Pp 297-307 (2023)
The physiological processes involved in adaptation to osmotic pressure in euryhaline crustaceans are highly energy demanding, but the effects of dietary lipids (fat) on low salinity adaptations have not been well evaluated. In the present study, a to
Externí odkaz:
https://doaj.org/article/ba8a80e3fa35480f883ae11c7fcc79c7
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Little is known about the association between gut microbiota and intestinal injury under a state of chronic cerebral hypoperfusion (CCH). Here, the effects of gut microbiota and short-chain fatty acids (SCFAs), as important metabo
Externí odkaz:
https://doaj.org/article/1b9fe9d46eb1471f8fac79269b38e870
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