Zobrazeno 1 - 10
of 976
pro vyhledávání: '"mitochondrial calcium uniporter"'
Autor:
Siyu Ren, Jianyu Wang, Zhanchen Dong, Jixun Li, Yu Ma, Ying Yang, Tian Zhou, Tianming Qiu, Liping Jiang, Qiujuan Li, Xiance Sun, Xiaofeng Yao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 280, Iss , Pp 116553- (2024)
The incidence of nonalcoholic steatohepatitis (NASH) is related with perfluorooctane sulfonate (PFOS), yet the mechanism remains ill-defined. Mounting evidence suggests that ferroptosis plays a crucial role in the initiation of NASH. In this study, w
Externí odkaz:
https://doaj.org/article/4d9bc418bcf746ee92febded4702132f
Autor:
Wanhong Li, Bowei Jia, Jiaxun Sheng, Yang Shen, Jun Jin, Xiaoli Sun, Xiangping Liu, Mingzhe Sun
Publikováno v:
Plants, Vol 13, Iss 22, p 3176 (2024)
The mitochondrial calcium uniporters (MCUs) are a family of calcium unidirectional transporters important for cytoplasmic Ca2+ signals. Though the MCU proteins in several plant species have been investigated, genome-wide analysis of MCUs in alfalfa i
Externí odkaz:
https://doaj.org/article/c3ccad6f80ee46109f67ce5893591d2e
Autor:
Zipeng Xu, Xia Chen, Haicun Zhou, Luming Sun, Ruobing Bai, Wenwen Yu, Junhao Yang, Hongbin Liu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveThe objective of this study is to elucidate the influence of MCU on the clinical pathological features of GC patients, to investigate the function and mechanism of the mitochondrial calcium uptake transporter MCU in the initiation and progre
Externí odkaz:
https://doaj.org/article/ff5a84604bc24e65b2986c6230ea4cd4
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 11, Pp 1342-1349 (2023)
Objective(s): Tumor metastasis is the leading cause of death in breast cancer (BC) patients and is a complicated process. Mitochondrial calcium uniporter (MCU), a selective channel responsible for mitochondrial Ca2+ uptake, has been reported to be as
Externí odkaz:
https://doaj.org/article/7baeae1085724c5e990d161782639c3c
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 19, Pp 1531-1542 (2023)
Xiaoxiao Xu, Bin Zhou, Jun Liu, Qianli Ma, Tengyu Zhang, Xiang Wu The First Hospital of Ningbo University, Ningbo, 315211, People’s Republic of ChinaCorrespondence: Xiang Wu, The First Hospital of Ningbo University, Ningbo, 315211, People’s Repub
Externí odkaz:
https://doaj.org/article/7da742e023234a00ad34d08d4206938d
Autor:
Emilia R. Gutiérrez-Mireles, José Carlos Páez-Franco, Raúl Rodríguez-Ruíz, Juan Manuel Germán-Acacio, M. Casandra López-Aquino, Manuel Gutiérrez-Aguilar
Publikováno v:
Plant Signaling & Behavior, Vol 18, Iss 1 (2023)
Plant metabolism is constantly changing and requires input signals for efficient regulation. The mitochondrial calcium uniporter (MCU) couples organellar and cytoplasmic calcium oscillations leading to oxidative metabolism regulation in a vast array
Externí odkaz:
https://doaj.org/article/41b9fffdc70c4541b298d9864535e163
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Ca2+ ions serve as pleiotropic second messengers in the cell, regulating several cellular processes. Mitochondria play a fundamental role in Ca2+ homeostasis since mitochondrial Ca2+ (mitCa2+) is a key regulator of oxidative metabolism and cell death
Externí odkaz:
https://doaj.org/article/1e77b78c320744f09b7d5e2cba0052ea
Autor:
Cai Hongyan, Qiao Jing, Chen Siru, Yang Junting, Hölscher Christian, Wang Zhaojun, Qi Jinshun, Wu Meina
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 54, Pp 1528-1539 (2022)
Alzheimer’s disease (AD) is a progressive and degenerative disorder accompanied by cognitive decline, which could be promoted by mitochondrial dysfunction induced by mitochondrial Ca 2+ (mCa 2+) homeostasis Mitochondrial calcium uniporter (MCU), a
Externí odkaz:
https://doaj.org/article/bb9c8433172d4c4798315c6512d5fdd4
Autor:
Robyn J. Novorolsky, Gracious D. S. Kasheke, Antoine Hakim, Marianna Foldvari, Gabriel G. Dorighello, Israel Sekler, Vidyasagar Vuligonda, Martin E. Sanders, Robert B. Renden, Justin J. Wilson, George S. Robertson
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The neurovascular unit (NVU) is composed of vascular cells, glia, and neurons that form the basic component of the blood brain barrier. This intricate structure rapidly adjusts cerebral blood flow to match the metabolic needs of brain activity. Howev
Externí odkaz:
https://doaj.org/article/4979afa4fa504c8a99e9f3addcc3efee
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