Zobrazeno 1 - 10
of 795
pro vyhledávání: '"mitochondria metabolism"'
Autor:
Mei-Qi Yang, Shu-Ling Zhang, Li Sun, Le-Tian Huang, Jing Yu, Jie-Hui Zhang, Yuan Tian, Cheng-Bo Han, Jie-Tao Ma
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Immune checkpoint blockade therapy has revolutionized cancer treatment, but resistance remains prevalent, often due to dysfunctional tumor-infiltrating lymphocytes. A key contributor to this dysfunction is mitochondrial dysfunction, characte
Externí odkaz:
https://doaj.org/article/bd16ca19c151423f9d4959ccda936bc3
Autor:
Zaigang Zhou, Cheng Li, Chao Li, Lei Zhou, Shuo Tan, Weibin Hou, Congying Xie, Long Wang, Jianliang Shen, Wei Xiong
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract It is newly revealed that collagen works as a physical barrier to tumor immune infiltration, oxygen perfusion, and immune depressor in solid tumors. Meanwhile, after radiotherapy (RT), the programmed death ligand‐1 (PD‐L1) overexpression
Externí odkaz:
https://doaj.org/article/1ecaacc15f814b1784b1d00812acc494
Autor:
Zaigang Zhou, Xin Jiang, Lei Yi, Cheng Li, Haoxiang Wang, Wei Xiong, Zhipeng Li, Jianliang Shen
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Currently, the typical combination therapy of programmed death ligand‐1 (PD‐L1) antibodies with radiotherapy (RT) still exhibits impaired immunogenic antitumor response in clinical due to lessened DNA damage and acquired immune tolerance
Externí odkaz:
https://doaj.org/article/89fdf6b883c046a6ab4d00aa0c36e3f9
Autor:
Yueming Yuan, An Fang, Haoran Wang, Caiqian Wang, Baokun Sui, Jianqing Zhao, Zhen F. Fu, Ming Zhou, Ling Zhao
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Infection with neurotropic viruses may result in changes in host behavior, which are closely associated with degenerative changes in neurons. The lyssavirus genus comprises highly neurotropic viruses, including the rabies virus (RABV), which
Externí odkaz:
https://doaj.org/article/c2405ab3063247c9bc6924bd25bc0aae
Autor:
Flávia Volpato Vieira, Rebeca Figueiredo Nalesso, Letícia Colin Panegossi, Icaro Alex'Sanderson Pereira Godoy, Jamila Cristina Baptistella, Tereza Cristina Cardoso
Publikováno v:
Pubvet, Vol 17, Iss 06 (2023)
Emerging coronavirus infections are a major threat to global public health. In this respect, a novel recombination of canine coronavirus (CCoV) and feline coronavirus (FCoV) was described among human biological samples, giving rise to a potential zoo
Externí odkaz:
https://doaj.org/article/1a321c1f51d24583b45c458a722c9324
Autor:
Makiko Mochizuki-Kashio, Noriko Otsuki, Kota Fujiki, Sherif Abdelhamd, Peter Kurre, Markus Grompe, Atsushi Iwama, Kayoko Saito, Ayako Nakamura-Ishizu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Fanconi Anemia (FA) is an inherited bone marrow (BM) failure disorder commonly diagnosed during school age. However, in murine models, disrupted function of FA genes leads to a much earlier decline in fetal liver hematopoietic stem cell (FL HSC) numb
Externí odkaz:
https://doaj.org/article/1549e69d8d5b4516bf6cdb405a36854c
Akademický článek
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Akademický článek
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Autor:
Tianshi Wang, Ying Cao, Haiyan Zhang, Zihao Wang, Cheuk Him Man, Yunfan Yang, Lingchao Chen, Shuangnian Xu, Xiaojing Yan, Quan Zheng, Yi‐Ping Wang
Publikováno v:
MedComm, Vol 3, Iss 3, Pp n/a-n/a (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) dysregulates antiviral signaling, immune response, and cell metabolism in human body. Viral genome and proteins hijack host metabolic network to support viral biogenesis and pr
Externí odkaz:
https://doaj.org/article/ada4cd8406aa4e52913e920227c47fe4
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCurcumin, a diarylheptanoid chemical compound extracted from curcuma longa, exerts a variety of biological and pharmacological effects in numerous pathological conditions, including ischemia/reperfusion (I/R) injury. In this study, we inves
Externí odkaz:
https://doaj.org/article/b1923e970046426188e2f8d3f083e4f7