Zobrazeno 1 - 10
of 511
pro vyhledávání: '"mismatch repair proteins"'
Autor:
Prof. Dr. Raluca‐Ioana Stefan‐van Staden, Alexandru Adrian Bratei, Dr. Ruxandra‐Maria Ilie‐Mihai, Damaris‐Cristina Gheorghe, Bianca Maria Tuchiu
Publikováno v:
ChemElectroChem, Vol 10, Iss 21, Pp n/a-n/a (2023)
Abstract Two stochastic microdisks were designed and validated for the DNA mismatch repair assessment in gastric and colon cancers, through determining simultaneously the concentrations of MLH1, MSH2, MSH6, PMS2, and of KRAS in whole blood, urine, sa
Externí odkaz:
https://doaj.org/article/0d73c4f75e29452bb1faa2d254cab69f
Publikováno v:
Zhongguo linchuang yanjiu, Vol 36, Iss 2, Pp 196-199 (2023)
Objective To investigate the clinicopathological significance of colorectal cancer with mesenteric tumor deposit(TD) and the relationship with DNA mismatch repair(MMR) protein expression. Methods The clinicopathological characteristics of 393 patient
Externí odkaz:
https://doaj.org/article/75fd08a2f5b344a3b3602397ab97ff02
Akademický článek
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Autor:
Dinisha Einstien, Gayathri Devi Thanigaimani, KS Mouleeswaran, A Prathiba, G Sarumathy, John Vergilin
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 17, Iss 6, Pp EC06-EC09 (2023)
Introduction: Microsatellite Instability (MSI) is the hallmark of Lynch syndrome/Constitutional Mismatch Repair Deficiency (CMMRD) and is also found in many sporadic cancers like colorectal cancer, endometrial, gastric, small intestine, urothelial, c
Externí odkaz:
https://doaj.org/article/3167fe1c28e743dd8860dbf11cb75029
Autor:
Maria Letizia Calandrella, Simona Francesconi, Cecilia Caprera, Claudia Mosillo, Claudia Caserta, Diana Giannarelli, Matteo Corsi, Serena Macrini, Annalisa Guida, Stefano Ascani, Sergio Bracarda
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Upper urinary tract urothelial carcinoma (UTUC) accounts for only about 5–10% of all urothelial cancers and is characterized by an aggressive and frequently rapidly fatal behavior. However, detailed knowledge of its molecular pr
Externí odkaz:
https://doaj.org/article/3941fb50bc194a1397376e4072713bb0
Autor:
Nic Gabriel Reitsam, Bruno Märkl, Sebastian Dintner, Johanna Waidhauser, Dmytro Vlasenko, Bianca Grosser
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immunohistochemical analysis of mismatch repair (MMR) protein expression is widely used to identify tumors with a deficient MMR (dMMR). MMR proteins (MLH1/PMS2 and MSH2/MSH6) work as functional heterodimers, which usually leads to the loss of express
Externí odkaz:
https://doaj.org/article/58b6fd5e238c4581a404ecaa9de48e7b
Autor:
Zhi Shang, Shengming Jin, Wenwen Wang, Yu Wei, Chengyuan Gu, Chen Yang, Yu Zhu, Yao Zhu, Yijun Shen, Junlong Wu, Dingwei Ye
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Expression of DNA mismatch repair (MMR) protein (MLH1, PMS2, MSH2, and MSH6) in upper tract urothelial carcinoma (UTUC) has been explored in Western cohorts, but it is rarely reported in Eastern cohorts. We aimed to assess the loss of MMR protein exp
Externí odkaz:
https://doaj.org/article/8d335e4c72a041d3b183f2b90becf0ae
Publikováno v:
Cancer Medicine, Vol 10, Iss 14, Pp 4743-4751 (2021)
Abstract Objective Neuroendocrine cervical cancer (NECC) is a rare cervical cancer with high aggressivity that causes poor prognosis even in the early stage. Given other neuroendocrine carcinomas and other types of cervical cancer have been proved to
Externí odkaz:
https://doaj.org/article/345c503ac84d40f58cf594a33144355f
Autor:
Carla Colombo, Gabriele Pogliaghi, Delfina Tosi, Marina Muzza, Gaetano Bulfamante, Luca Persani, Laura Fugazzola, Valentina Cirello
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
To date, the molecular mechanisms that underline aggressiveness and resistance to tyrosine kinase inhibitors in some thyroid carcinomas (TCs) are not known yet. We report the case of a young patient with a metastatic poorly differentiated (PDTC) and
Externí odkaz:
https://doaj.org/article/6b52e8ae75c647358805450d7a4674c0
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 64, Iss 1, Pp 132-135 (2021)
Primary adenocarcinoma of the urinary bladder is a rare malignancy with a frequency of less than 2% of all urothelial malignancies. Colonic adenocarcinoma has a much higher prevalence and its infiltration/metastasis in the urinary bladder is a pertin
Externí odkaz:
https://doaj.org/article/3a57f8efe0904b319fbb74f6021b794d