Zobrazeno 1 - 10
of 177
pro vyhledávání: '"mirna sponges"'
Autor:
Rabia KALKAN CAKMAK, Nail BESLI, Bahar SARIKAMIS JOHNSON, Nilufer ERCIN, Hayati Sencer POLAT, Ulkan KILIC
Publikováno v:
Bezmiâlem Science, Vol 12, Iss 4, Pp 413-420 (2024)
Objective: Alzheimer’s disease (AD) is a neurodegenerative ailment that launches insidiously and progresses slowly, and its prevalence gradually increases with age. In a former study, we explored the plasma exosomal circular RNA (circRNA)-micro RNA
Externí odkaz:
https://doaj.org/article/72a2b6582f764813abb28e7483ddb6bb
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 24, Iss 2, Pp 140-156 (2024)
INTRODUCTION. The development of malignant neoplasms is associated with changes in the expression of small non-coding RNAs (miRNAs). This emphasises the need for research into the development of miRNA-targeted inhibitors as a promising approach to ca
Externí odkaz:
https://doaj.org/article/6690babde4ae4d89b7cb5b8712c94f88
Autor:
A.E. Abaturov, V.L. Babуch
Publikováno v:
Zdorovʹe Rebenka, Vol 18, Iss 8, Pp 572-583 (2023)
The scientific review provides the mechanisms of drug regulation of microRNA in the human body. To write the article, information was searched using Scopus, Web of Science, MEDLINE, PubMed, Google Scholar, Embase, Global Health, The Cochrane Library
Externí odkaz:
https://doaj.org/article/338ca164c34f4879a8b7a6f2ec84e235
Publikováno v:
Cells, Vol 12, Iss 24, p 2813 (2023)
CircRNAs are a category of regulatory RNAs that have garnered significant attention in the field of regulatory RNA research due to their structural stability and tissue-specific expression. Their circular configuration, formed via back-splicing, resu
Externí odkaz:
https://doaj.org/article/5c0eb44b12d047ac86c82f07dfd97c76
Publikováno v:
Animal Models and Experimental Medicine, Vol 5, Iss 1, Pp 38-47 (2022)
Abstract Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single‐stranded transcript. They are a novel class of genomic regulators that are linked to many important development and disease processes and are being pursued as cli
Externí odkaz:
https://doaj.org/article/82f46373c1f5485e80077c84cdc6b33c
Publikováno v:
Non-Coding RNA, Vol 9, Iss 4, p 38 (2023)
Circular RNAs (circRNAs) represent single-stranded RNA species that contain covalently closed 3′ and 5′ ends that provide them more stability than linear RNA, which has free ends. Emerging evidence indicates that circRNAs perform essential functi
Externí odkaz:
https://doaj.org/article/4caa98bec1ca4a59a12abdb62df7b5a0
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Triple-negative breast cancer (TNBC) is a special type of breast cancer that lacks effective therapeutic targets. There is a significant need to clarify its pathogenesis, so as to bring new targeted approaches for TNBC management.
Externí odkaz:
https://doaj.org/article/db522db6267c46fda0c28fc033f34092
Autor:
Sabah Nisar, Ajaz A. Bhat, Mayank Singh, Thasni Karedath, Arshi Rizwan, Sheema Hashem, Puneet Bagga, Ravinder Reddy, Farrukh Jamal, Shahab Uddin, Gyan Chand, Davide Bedognetti, Wael El-Rifai, Michael P. Frenneaux, Muzafar A. Macha, Ikhlak Ahmed, Mohammad Haris
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be aberrant RNA splicing by-products with decreased functionality. However, rece
Externí odkaz:
https://doaj.org/article/7399d2a0f846486c93986da2f47d9637
Autor:
Zitao Chen, Xiangchun Pan, Yaru Kong, Yao Jiang, Yuyi Zhong, Hao Zhang, Zhe Zhang, Xiaolong Yuan, Jiaqi Li
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Being the center of the hypothalamus-pituitary-ovary (HPO) axis, the pituitary plays a key role in the onset of puberty. Recent studies show that circular RNAs (circRNAs) can perform as miRNA sponges to regulate development in animals. However, the f
Externí odkaz:
https://doaj.org/article/94d98644e0254c55a0439f47b6ea5156
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 1, Pp 342-352 (2018)
Background/Aims: A growing body of evidence has suggested that circular RNAs (circRNAs) have crucial functions in the regulation of gene expression, and their dysregulation has been implicated in various types of cancers. However, the roles of circRN
Externí odkaz:
https://doaj.org/article/528181c7afbb4e0a81d090bc8de38bb6