Zobrazeno 1 - 10
of 314
pro vyhledávání: '"mir-494"'
Publikováno v:
Journal of Trace Elements and Minerals, Vol 9, Iss , Pp 100176- (2024)
Background/objectives: Inflammation and oxidative stress play a significant role in renal ischemia-reperfusion injury (RIRI). This study aimed to investigate the possible protective effects of pretreatment with sodium selenite on RIRI, emphasizing an
Externí odkaz:
https://doaj.org/article/0acb1d1ddc124a83a7f34a42b13b3960
Autor:
Christian Bergamini, Ilaria Leoni, Nicola Rizzardi, Mattia Melli, Giuseppe Galvani, Camelia Alexandra Coada, Catia Giovannini, Elisa Monti, Irene Liparulo, Francesca Valenti, Manuela Ferracin, Matteo Ravaioli, Matteo Cescon, Francesco Vasuri, Fabio Piscaglia, Massimo Negrini, Claudio Stefanelli, Romana Fato, Laura Gramantieri, Francesca Fornari
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-23 (2023)
Abstract Background Metabolic reprogramming is a well-known marker of cancer, and it represents an early event during hepatocellular carcinoma (HCC) development. The recent approval of several molecular targeted agents has revolutionized the manageme
Externí odkaz:
https://doaj.org/article/34250187980d4eea86e716eacbf07965
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background Increasing evidence suggests that mitophagy is responsible for the pathogenesis of intervertebral disk (IVD) degeneration. Previous studies have shown that Duhuo Jisheng Decoction (DHJSD), a classic Fangji of traditional Chinese m
Externí odkaz:
https://doaj.org/article/f0af7dfb80ec4d7ba904b61aec49e6fa
Autor:
Zhongxian Tian, Xiaohui Hua, Junlan Zhu, Peiwei Li, Ruifan Chen, Xin Li, Tengda Li, Chengfan Zhou, Chuanshu Huang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 263, Iss , Pp 115273- (2023)
Lung cancer primarily arises from exposure to various environmental factors, particularly airborne pollutants. Among the various lung carcinogens, benzo(a)pyrene and its metabolite B[a]PDE are the strongest ones that actively contribute to lung cance
Externí odkaz:
https://doaj.org/article/72dc87aabcec49fe811cc8c4eafe03d5
Publikováno v:
Autoimmunity, Vol 55, Iss 5, Pp 318-327 (2022)
Acute lung injury (ALI) is a common, variously induced lung cell injury with high mortality. It is also an early stage of acute respiratory distress syndrome. BML-111 is a lipoxin A4 receptor agonist that plays an important role in inflammation. Howe
Externí odkaz:
https://doaj.org/article/c34c62d03b2e4d7fa0db4ed7dce9f8ba
Autor:
Theodore Leng, Georgia Kamboj, Xiaoyun Sun, Heather Chang, Prisha Davda, Majesty Greer, Creed M. Stary
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Epiretinal membranes (ERMs) are the result of fibro-cellular proliferation that cause distortion and impairment of central vision. We hypothesized that select microRNAs (miRs) regulate retinal fibro-proliferation and ERM formation. Following IRB appr
Externí odkaz:
https://doaj.org/article/10efe51c974b4a26aecc295048cbd473
Autor:
Hongchang Li, Xianhao Sun, Jindong Li, Weiyan Liu, Gaofeng Pan, Anwei Mao, Jiazhe Liu, Qing Zhang, Longhua Rao, Xiaofeng Xie, Xia Sheng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100821- (2022)
Cytotoxic chemotherapy is the major strategy to prevent and reduce triple-negative breast cancer (TNBC) progression and metastasis. Hypoxia increases chemoresistance and is associated with a poor prognosis for patients with cancer. Based on accumulat
Externí odkaz:
https://doaj.org/article/fdc2ddae048b4c2f998605af1646512d
Akademický článek
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Autor:
Adam Hermawan, Herwandhani Putri
Publikováno v:
Journal of the Egyptian National Cancer Institute, Vol 32, Iss 1, Pp 1-10 (2020)
Abstract Background The focus of trastuzumab resistance biomarkers in recent decades has been on epigenetic and non-coding RNA-based mechanisms. In this study, the potential of miR-494 and its target genes as predictive biomarkers for breast cancer (
Externí odkaz:
https://doaj.org/article/998712d6a2e547e585b0744d33a82483
Autor:
Daniella P. Vansteenkiste, Joelle M. Fenger, Paolo Fadda, Paula Martin‐Vaquero, Ronaldo C. daCosta
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 6, Pp 2685-2692 (2019)
Abstract Background Osseous‐associated cervical spondylomyelopathy (OA‐CSM) is a common condition of the cervical vertebral column that affects giant dog breeds. MicroRNAs (miRNAs) are small RNAs that regulate gene expression, and recent data sug
Externí odkaz:
https://doaj.org/article/df687f1e2ce34a81abca4e007f6b508d