Zobrazeno 1 - 10
of 1 125
pro vyhledávání: '"mir-137"'
Autor:
Shengyun Xu, Jiaoxiang Wang, Kexin Mao, Deling Jiao, Zhu Li, Heng Zhao, Yifei Sun, Jin Feng, Yuanhao Lai, Ruiqi Peng, Yu Fu, Ruoyi Gan, Shuhan Chen, Hong-Ye Zhao, Hong-Jiang Wei, Ying Cheng
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background Neurodevelopmental disorders (NDD), such as autism spectrum disorders (ASD) and intellectual disorders (ID), are highly debilitating childhood psychiatric conditions. Genetic factors are recognized as playing a major role in NDD,
Externí odkaz:
https://doaj.org/article/0e51734de2d9473fa312a94faec51e77
Autor:
Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang, Mengyue Li, Linlin Fan, Xin Zeng, Xinrui Ma, Danyang Zheng, Han Wang, Hui Wang, Hao Liu, Shengjun Liang, Lijie Wu, Shuang Liang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-derived extrac
Externí odkaz:
https://doaj.org/article/002a87ae1a2842e299732e67bb7af3e3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Lung cancer is a prevalent malignancy and the leading cause of cancer-related deaths, posing a significant threat to human health. Despite advancements in treatment, the prognosis for lung cancer patients remains poor due to late diagnosis, cancer re
Externí odkaz:
https://doaj.org/article/e2643917e73f46559ebf69b9717beb1a
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31372- (2024)
Long-term isoflurane inhalation has been reported to induce hippocampal apoptosis in young animals, whereas dexmedetomidine (DEX) can reduce isoflurane-induced neuronal apoptosis. The neuroprotective effect of miR-137 has been reported before, howeve
Externí odkaz:
https://doaj.org/article/7d47ea88e7824100bbbb33def609a8f6
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7229 (2024)
Neurodegenerative diseases affect an increasing part of the population of modern societies, burdening healthcare systems and causing immense suffering at the personal level. The pathogenesis of several of these disorders involves dysregulation of gen
Externí odkaz:
https://doaj.org/article/e30d4c8897ea490085aeef63fbf00e34
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Purpose As the global population ages rapidly, osteoporotic fractures have become an important public health problem. Previous studies have suggested that miR-137 is involved in the regulation of bone formation, but its specific regulatory m
Externí odkaz:
https://doaj.org/article/5f6821a998e54875a7af59400952e67f
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 6, Pp 596-604 (2023)
Abstract Tanshinone IIA (Tan IIA) has an important role in treatment of cardiovascular diseases, including atherosclerosis. The vascular smooth muscle cells (VSMCs) are a major part of the atherosclerotic plaque. However, the biological functions of
Externí odkaz:
https://doaj.org/article/e6552918832c45dba3ee667040647814
Publikováno v:
Cancer Biology & Therapy, Vol 24, Iss 1 (2023)
Background The function of long non-coding RNA (lncRNA) MALAT1 in regulating triple-negative breast cancer (TNBC) stemness and tumorigenesis was investigated. Methods Sphere formation and colony formation assays coupled with flow cytometry were emplo
Externí odkaz:
https://doaj.org/article/b48d8bf29c4c433988e83f1a069d65dc
Autor:
Behnaz Khavari, Michelle M. Barnett, Ebrahim Mahmoudi, Michael P. Geaghan, Adam Graham, Murray J. Cairns
Publikováno v:
Life, Vol 14, Iss 5, p 562 (2024)
Oxidative stress is one of the most important environmental exposures associated with psychiatric disorders, but the underlying molecular mechanisms remain to be elucidated. In a previous study, we observed a substantial alteration of the gene expres
Externí odkaz:
https://doaj.org/article/8067494e375d48fa9d286adefe0c8708