Zobrazeno 1 - 2
of 2
pro vyhledávání: '"minor variant finder"'
Autor:
T. N. Subbotina, I. E. Maslyukova, A. A. Faleeva, P. A. Nikolaeva, A. S. Khazieva, E. A. Dunaeva, K. O. Mironov, L. B. Polushkina, I. S. Martynkevich, S. V. Vereshchagina, B. V. Barankin
Publikováno v:
Онкогематология, Vol 15, Iss 2, Pp 85-91 (2020)
Background. There are problems related to both quantitative assessment of an allele burden level of a mutant gene and interpretation of results in DNA samples with the burden level of the mutant allele less than 15–20 %, when using Sanger sequencin
Externí odkaz:
https://doaj.org/article/bc3b0376a2864fffaa914ecdf25e92fa
Autor:
Irina Evgenevna Maslyukova, Anastasia Aleksandrovna Karnyushka, Tatiana Nikolaevna Subbotina, Anna Sergeevna Hazieva, Elena Aleksandrovna Dunaeva, Konstantin Olegovich Mironov
Publikováno v:
Siberian Journal of Life Sciences and Agriculture, Vol 11, Iss 5-2, Pp 73-78 (2019)
The somatic mutation of JAK2 p. 1849 G> T (V617F) leads to cytokine-independent growth of bone marrow cell lines. It is one of the diagnostic criteria for chronic myeloproliferative neoplasm. Sanger sequencing is the gold standard for analyzing this
Externí odkaz:
https://doaj.org/article/be66360072d44231a798d0d402f295da