Zobrazeno 1 - 10
of 893
pro vyhledávání: '"microtubule-associated protein tau"'
Autor:
Yajun Zhang, Yuqian Wang, Haiping Dou, Shanshan Wang, Danyang Qu, Xin Peng, Ning Zou, Liu Yang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
AimsWhite matter damage (WMD) is linked to both cerebral palsy and cognitive deficits in infants born prematurely. The focus of this study was to examine how caffeine influences the acetylation of proteins within the neonatal white matter and to eval
Externí odkaz:
https://doaj.org/article/599af8a086ed4b32961086b11dca6b3f
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 508 (2024)
Microtubule-associated protein Tau (MAPT) is strongly associated with the development of neurodegenerative diseases. In addition to driving the formation of neurofibrillary tangles (NFT), mutations in the MAPT gene can also cause oxidative stress thr
Externí odkaz:
https://doaj.org/article/7b5d9316109047299c836f5e111e7b20
Autor:
Neil Donison, Matthew Hintermayer, Maegha Subramaniam, Erin Santandrea, Kathryn Volkening, Michael J. Strong
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Phosphorylated microtubule-associated protein tau (tau) aggregates are a pathological hallmark of various neurodegenerative diseases, including chronic traumatic encephalopathy and amyotrophic lateral sclerosis with cognitive impairment. While there
Externí odkaz:
https://doaj.org/article/2299cbd01d6043df929240c2af22b231
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract Synaptic degeneration is a precursor of synaptic and neuronal loss in neurodegenerative diseases such as Alzheimer’s disease (AD) and frontotemporal dementia with tau pathology (FTD-tau), a group of primary tauopathies. A critical role in
Externí odkaz:
https://doaj.org/article/373093bdf15547e2980ab7ec67eb4114
Akademický článek
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Autor:
Rayane Hedna, Attilio DiMaio, Maxime Robin, Diane Allegro, Mario Tatoni, Vincent Peyrot, Pascale Barbier, Hervé Kovacic, Gilles Breuzard
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15050 (2023)
Tau protein has been described for several decades as a promoter of tubulin assembly into microtubules. Dysregulation or alterations in Tau expression have been related to various brain cancers, including the highly aggressive and lethal brain tumor
Externí odkaz:
https://doaj.org/article/4440b53af0b84dbba4580abc12b71dea
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Zhi Ruan, Jean-Christophe Delpech, Srinidhi Venkatesan Kalavai, Alicia A. Van Enoo, Jianqiao Hu, Seiko Ikezu, Tsuneya Ikezu
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Neuronal accumulation of misfolded microtubule-associated protein tau is a hallmark of neuropathology in Alzheimer’s disease, frontotemporal dementia, and other tauopathies, and has been a therapeutic target. Microglia can sprea
Externí odkaz:
https://doaj.org/article/2a1a291cc9424f7d8922c6b52239d88a
Autor:
Yuxing Xia, Stefan Prokop, Kimberly-Marie M. Gorion, Justin D. Kim, Zachary A. Sorrentino, Brach M. Bell, Alyssa N. Manaois, Paramita Chakrabarty, Peter Davies, Benoit I. Giasson
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Tau protein abnormally aggregates in tauopathies, a diverse group of neurologic diseases that includes Alzheimer’s disease (AD). In early stages of disease, tau becomes hyperphosphorylated and mislocalized, which can contribute to its aggr
Externí odkaz:
https://doaj.org/article/9267b6611e3e4525a29fc05172e583f1