Zobrazeno 1 - 10
of 790
pro vyhledávání: '"microglial polarization"'
Autor:
Federica Felice, Pamela De Falco, Martina Milani, Serena Castelli, Antonella Ragnini-Wilson, Giacomo Lazzarino, Nadia D’Ambrosi, Fabio Ciccarone, Maria Rosa Ciriolo
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Microglia play a crucial role in brain development and repair by facilitating processes such as synaptic pruning and debris clearance. They can be activated in response to various stimuli, leading to either pro-inflammatory or ant
Externí odkaz:
https://doaj.org/article/c9d3accd016e4fbdad83968c2173dfab
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 6143-6158 (2024)
Lei Wang,1,* Kai Wang,2,* Yuwen Chen,1 Xiaoyu Zhang,1,3 Wenhao Xu,1,3 Zhong Dong,1,3 Yu Wang1,3,4 1Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, 230000, People’s Republic of China
Externí odkaz:
https://doaj.org/article/d2f4bd8e589047d28f38c6090c2341e9
Autor:
Jing Cheng, Han Yu, Zhi-Feng Zhang, Hong-Xiang Jiang, Ping Wu, Zhou-Guang Wang, Zhi-Biao Chen, Li-Quan Wu
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 35, Iss 1, Pp 1-17 (2024)
Abstract Studies have shown that the inhibition of phosphatase and tensin homolog deleted on chromosome 10 (PTEN)was neuroprotective against ischemia/reperfusion(I/R) injury. Bisperoxovanadium (bpV), a derivative of vanadate, is a well-established in
Externí odkaz:
https://doaj.org/article/f87f12d2544944d0a11db3f92c5d6f6a
Autor:
Jing-Hao Liang, Yue-Hui Zheng, An-Hao Guo, Heng Yu, Chuan-peng Xia, Zhe-Yu Zhang, Long Wu, Hede Yan
Publikováno v:
Journal of Functional Foods, Vol 121, Iss , Pp 106424- (2024)
Astaxanthin (ATX), a naturally occurring carotenoid, exhibits notable neuroprotective properties, including anti-inflammatory effects and regulation of neurotrophic factors. This study investigates the fundamental processes by which astaxanthin facil
Externí odkaz:
https://doaj.org/article/ca312e67c09e47568377729bf526a5e7
Autor:
Xiaoxiang Hou, Xiaolin Qu, Wen Chen, Xianzheng Sang, Yichao Ye, Chengqing Wang, Yangu Guo, Hantong Shi, Chengzi Yang, Kaixin Zhu, Yelei Zhang, Haoxiang Xu, Liquan Lv, Danfeng Zhang, Lijun Hou
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background White matter injury (WMI) represents a significant etiological factor contributing to neurological impairment subsequent to Traumatic Brain Injury (TBI). CD36 receptors are recognized as pivotal participants in the pathogenesis of
Externí odkaz:
https://doaj.org/article/e36dfd09c55c4ec399fe9311e3b30c96
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-18 (2024)
Abstract Microglial activation and polarization play a central role in poststroke inflammation and neuronal damage. Modulating microglial polarization from pro-inflammatory to anti-inflammatory phenotype is a promising therapeutic strategy for the tr
Externí odkaz:
https://doaj.org/article/9988bd25b11843ef81b479c4a95244f1
Autor:
Yunji Yan, Shengwei Bai, Hongxi Han, Junqiang Dai, Liang Niu, Hongyu Wang, Qiang Dong, Hang Yin, Guoqiang Yuan, Yawen Pan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background In the tumor immune microenvironment (TIME), triggering receptor expressed on myeloid cells 2 (trem2) is widely considered to be a crucial molecule on tumor-associated macrophages(TAMs). Multiple studies have shown that trem2 may
Externí odkaz:
https://doaj.org/article/535ade0e5bc9434cbc4acb0765fee23c
Autor:
Xin Zhong, Shiqiang Gong, Linghui Meng, Weifan Yao, Ke Du, Linchi Jiao, Guowei Ma, Jingwei Liang, Binbin Wei, Xin Jin, Junhui Tong, Jianru Dong, Mengyu Liu, Menglin Gao, Huachao Jia, Wenjuan Jiang, Zhihua Yu, Yanzhe Wang, Xiaohong Sun, Minjie Wei, Mingyan Liu
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract The microenvironment mediated by the microglia (MG) M1/M2 phenotypic switch plays a decisive role in the neuronal fate and cognitive function of Alzheimer's disease (AD). However, the impact of metabolic reprogramming on microglial polarizat
Externí odkaz:
https://doaj.org/article/0666a0aaca4144688d40ec72167bc343
Autor:
Yuluo Rong, Jiaxing Wang, Tao Hu, Zhongming Shi, Chuandong Lang, Wei Liu, Weihua Cai, Yongjin Sun, Feng Zhang, Wenzhi Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Spinal cord injury (SCI) is a severe neurological condition that frequently leads to significant sensory, motor, and autonomic dysfunction. This study sought to delineate the potential mechanistic underpinnings of extracellular vesicles (EVs
Externí odkaz:
https://doaj.org/article/2c00a71a026642048f343f0a79dc8bc3
Autor:
Kai Wang, Shujie Zan, Jiachun Xu, Weiming Sun, Caixia Li, Wei Zhang, Daoyan Ni, Ruzhen Cheng, Lin Li, Zhen Yu, Linlin Zhang, Shuang Liu, Yuanwu Cui, Yulian Zhang
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35800- (2024)
Abstrct: Background: Aging is the primary risk factor for the onset of Alzheimer's disease (AD). Inflamma-aging is a major feature in the process of aging, and the chronic neuroinflammation caused by inflamma-aging is closely related to AD. As the ma
Externí odkaz:
https://doaj.org/article/c39e1b8d682f49b68f648c18a69afaa4