Zobrazeno 1 - 10
of 4 209
pro vyhledávání: '"microglial cells"'
Publikováno v:
mSystems, Vol 9, Iss 10 (2024)
ABSTRACT Nocardia farcinica can cause a rare, yet potentially fatal, central nervous system infection. NbtS protein may be a key virulence factor in N. farcinica infection of the brain. In this study, we investigated the function of the virulence-ass
Externí odkaz:
https://doaj.org/article/3e74ead0e20e463a9e1b8cbddc7b9862
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 762320-45 (2024)
Sepsis is defined as a dysregulated host response to infection resulting in life-threatening organ dysfunction. Sepsis-associated encephalopathy (SAE) is the main manifestation of sepsis. Inflammation, peroxidation stress injury, and apoptosis are th
Externí odkaz:
https://doaj.org/article/a2b234f0f81346dfa78ee7fbaad6c185
Autor:
Songhomitra Panda-Jonas, MD, Rahul A. Jonas, MD, Jie Xu, MD, Ya Xing Wang, MD, Jost B. Jonas, MD
Publikováno v:
Ophthalmology Science, Vol 5, Iss 2, Pp 100626- (2025)
Purpose: To examine intraretinally migrated retinal pigment epithelium cells (iRPECs) in enucleated human eyes with various retinal conditions and corresponding intraretinal hyperreflective bodies (iHRBs) in a large cohort of patients with age-relate
Externí odkaz:
https://doaj.org/article/164c14aec75c420dbe075da5e39f1069
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f6601993880f4aa2938a8a613eaac4f4
Autor:
Huang, Caoxin a, 1, ⁎, Zhang, Xiaofang a, 1, Wu, Menghua a, Yang, Chen a, Ge, Xilin a, Chen, Wenting a, Li, Xuejun a, Liu, Suhuan a, b, ⁎, Yang, Shuyu a, c, ⁎
Publikováno v:
In International Immunopharmacology 10 January 2025 144
Autor:
Yi Tian, Xiao Xiao, Weiliang Liu, Shanqing Cheng, Na Qian, Ling Wang, Yang Liu, Rong Ai, Xiaoping Zhu
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Autism spectrum disorder (ASD) encompasses a diverse range of neurodevelopmental disorders, but the precise underlying pathogenesis remains elusive. This study aim to explore the potential mechanism of TREM2 in regulating microgli
Externí odkaz:
https://doaj.org/article/7a826b1cbf2e4f079417e2edf65d4e6f
Autor:
Maria Cristina Barbalace, Michela Freschi, Irene Rinaldi, Lorenzo Zallocco, Marco Malaguti, Clementina Manera, Gabriella Ortore, Mariachiara Zuccarini, Maurizio Ronci, Doretta Cuffaro, Marco Macchia, Silvana Hrelia, Laura Giusti, Maria Digiacomo, Cristina Angeloni
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1074 (2024)
Neuroinflammation is a critical aspect of various neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases. This study investigates the anti-neuroinflammatory properties of oleocanthal and its oxidation product, oleocanthalic acid
Externí odkaz:
https://doaj.org/article/d9f544849f184aaabd43dac2b700cf24
Autor:
Louise H. Lefrançois, Jahn Nitschke, Huihai Wu, Gaël Panis, Julien Prados, Rachel E. Butler, Tom A. Mendum, Nabil Hanna, Graham R. Stewart, Thierry Soldati
Publikováno v:
mSystems, Vol 9, Iss 2 (2024)
ABSTRACTTuberculosis remains the most pervasive infectious disease and the recent emergence of drug-resistant strains emphasizes the need for more efficient drug treatments. A key feature of pathogenesis, conserved between the human pathogen Mycobact
Externí odkaz:
https://doaj.org/article/6f8ef12fa85142f6917fe6f2d44a0b6b
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Depression has long been considered a disease involving immune hyperactivation. The impact of pro-inflammatory cytokines such as TNF-α, IL-1β, IL-6, and IL-8 on depression has been widely studied. However, the effect of IL-33, another pro-inflammat
Externí odkaz:
https://doaj.org/article/61f44db5a9284a2e8369cc074a85d01e
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 2, Pp 253-257 (2023)
Although little attention has been paid to cognitive and emotional dysfunctions observed in patients after spinal cord injury, several reports have described impairments in cognitive abilities. Our group also has contributed significantly to the stud
Externí odkaz:
https://doaj.org/article/dd3f30d2f37e4f21a49e8f581a08cc6f