Zobrazeno 1 - 10
of 3 622
pro vyhledávání: '"microelectrode array"'
Publikováno v:
Pharmacological Research, Vol 209, Iss , Pp 107436- (2024)
Alzheimer's disease is characterized by the aggregation of β-amyloid, a pathological feature believed to drive the neuronal loss and cognitive decline commonly seen in the disease. Given the growing prevalence of this progressive neurodegenerative d
Externí odkaz:
https://doaj.org/article/8a67380942314e249a15681836adb4a6
Autor:
Jihyun Lee, Eliane Duperrex, Ibrahim El-Battrawy, Alyssa Hohn, Ardan M. Saguner, Firat Duru, Vishalini Emmenegger, Lukas Cyganek, Andreas Hierlemann, Hasan Ulusan
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionIn recent years, high-density microelectrode arrays (HD-MEAs) have emerged as a valuable tool in preclinical research for characterizing the electrophysiology of human induced pluripotent stem-cell-derived cardiomyocytes (iPSC-CMs). HD-ME
Externí odkaz:
https://doaj.org/article/a027b4206ff64aacbc594cc330d8ac9b
Autor:
Iliana E Bray, Stephen E Clarke, Kerriann M Casey, Paul Nuyujukian, for the Brain Interfacing Laboratory
Publikováno v:
eLife, Vol 12 (2024)
Lesion studies have historically been instrumental for establishing causal connections between brain and behavior. They stand to provide additional insight if integrated with multielectrode techniques common in systems neuroscience. Here, we present
Externí odkaz:
https://doaj.org/article/89826b64d0e14d0fad398699e7000e35
Autor:
Noora Räsänen, Jari Tiihonen, Marja Koskuvi, Šárka Lehtonen, Nelli Jalkanen, Nelli Karmila, Isabelle Weert, Olli Vaurio, Ilkka Ojansuu, Markku Lähteenvuo, Olli Pietiläinen, Jari Koistinaho
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 4, Pp 100313- (2024)
Background: Development of synaptic activity is a key neuronal characteristic that relies largely on interactions between neurons and astrocytes. Although astrocytes have known roles in regulating synaptic function and malfunction, the use of human-
Externí odkaz:
https://doaj.org/article/e7359c272ddf44e5beee97c07010e73c
Autor:
Emilie Puginier, Karen Leal-Fischer, Julien Gaitan, Marie Lallouet, Pier-Arnaldo Scotti, Matthieu Raoux, Jochen Lang
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundPancreatic islets are important in nutrient homeostasis and improved cellular models of clonal origin may very useful especially in view of relatively scarce primary material. Close 3D contact and coupling between β-cells are a hallmark of
Externí odkaz:
https://doaj.org/article/8c6ce2d72bcf4b8a945a0a37c3ff899e
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
With cancer as one of the leading causes of death worldwide, there is a need for the development of accurate, cost-effective, easy-to-use, and fast drug-testing assays. While the NCI 60 cell-line screening as the gold standard is based on a colorimet
Externí odkaz:
https://doaj.org/article/b1ab2aa1b247446db1ac3291d5e3d281
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Flexible high-density microelectrode arrays (HDMEAs) are emerging as a key component in closed-loop brain–machine interfaces (BMIs), providing high-resolution functionality for recording, stimulation, or both. The flexibility of these arrays provid
Externí odkaz:
https://doaj.org/article/c3790900597f4500aa4441f57029ab67
Autor:
Ell Maximilian, Zeck Günther
Publikováno v:
Current Directions in Biomedical Engineering, Vol 9, Iss 2, Pp 16-18 (2023)
Detecting cells on substrates time-continuously without the need of optical microscopy is broad interest in biotechnological applications. We demonstrate the stability and repeatability of a method to detect cancer cells using cell adhesion noise spe
Externí odkaz:
https://doaj.org/article/75581bdcc7a94ec4b2e2310a103c089f
Autor:
Rachel Van Duyne, Elena Irollo, Angel Lin, James A. Johnson, Alain M. Guillem, Erick V. O’Brien, Laura Merja, Bradley Nash, Joshua G. Jackson, Atom Sarkar, Zachary A. Klase, Olimpia Meucci
Publikováno v:
Cells, Vol 13, Iss 13, p 1127 (2024)
HIV-associated neurocognitive disorders (HAND) persist under antiretroviral therapy as a complex pathology that has been difficult to study in cellular and animal models. Therefore, we generated an ex vivo human brain slice model of HIV-1 infection f
Externí odkaz:
https://doaj.org/article/306ea5e6bf6e4dcdabacd95052e8aecf