Zobrazeno 1 - 10
of 1 260
pro vyhledávání: '"microcrystal"'
Autor:
Laurens Bourda, Subhrajyoti Bhandary, Sho Ito, Christian R. Göb, Pascal Van Der Voort, Kristof Van Hecke
Publikováno v:
IUCrJ, Vol 11, Iss 4, Pp 510-518 (2024)
Although COF-300 is often used as an example to study the synthesis and structure of (3D) covalent organic frameworks (COFs), knowledge of the underlying synthetic processes is still fragmented. Here, an optimized synthetic procedure based on a combi
Externí odkaz:
https://doaj.org/article/bf1ba850e546468a82883d5c48b3540c
Publikováno v:
IUCrJ, Vol 11, Iss 3, Pp 309-324 (2024)
Dynamical refinement is a well established method for refining crystal structures against 3D electron diffraction (ED) data and its benefits have been discussed in the literature [Palatinus, Petříček & Corrêa, (2015). Acta Cryst. A71, 235–244;
Externí odkaz:
https://doaj.org/article/2ae573aaf9b942648b8aefb7001df070
Autor:
Livia Deris Prado, Isabella Costa Ramos de Castro, Karen Medeiros Gonçalves, Thamyrys Barreto Argenta, Leandro Tasso, Helvécio Vinícius Antunes Rocha
Publikováno v:
Química Nova, Vol 48, Iss 2 (2024)
Efavirenz, an antiretroviral drug, is a class 2 according to the biopharmaceutics classification system. Many dissolution enhancement systems have been tried and our group had success using wet milling to decrease particle size and granules were obta
Externí odkaz:
https://doaj.org/article/162d04bd0fa345b7841705212392a85e
Publikováno v:
Journal of Structural Biology: X, Vol 10, Iss , Pp 100107- (2024)
Clostripain secreted from Clostridium histolyticum is the founding member of the C11 family of Clan CD cysteine peptidases, which is an important group of peptidases secreted by numerous bacteria. Clostripain is an arginine-specific endopeptidase. Be
Externí odkaz:
https://doaj.org/article/f8ebe8552c8544a8b6e77f0a351d2084
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract Quantitative analysis of complex mixtures, including compounds having similar chemical properties, is demonstrated using an automatic and high throughput approach to microcrystal electron diffraction (MicroED). Compositional analysis of orga
Externí odkaz:
https://doaj.org/article/81f681c703b346feb17bb71886282940
Publikováno v:
Journal of Structural Biology: X, Vol 9, Iss , Pp 100102- (2024)
Microcrystal electron diffraction (MicroED) has emerged as a powerful technique for unraveling molecular structures from microcrystals too small for X-ray diffraction. However, a significant hurdle arises with plate-like crystals that consistently or
Externí odkaz:
https://doaj.org/article/8535d678483245299ce21056f86413f3
Autor:
R. Beanland
Publikováno v:
IUCrJ, Vol 11, Iss 3, Pp 277-278 (2024)
Over 30 years ago, it was shown that bonding between atoms has a noticeable effect on convergent beam electron diffraction patterns. The paper by Olech et al. [(2024). IUCrJ, 11, 309–324] demonstrates that its influence is also clearly present in 3
Externí odkaz:
https://doaj.org/article/8fb969c3d43b4c3c84e5fa283debed06
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Meclizine (Antivert, Bonine) is a first‐generation H1 antihistamine used in the treatment of motion sickness and vertigo. Despite its wide medical use for over 70 years, its crystal structure and the details of protein‐drug interactions
Externí odkaz:
https://doaj.org/article/8fbba48bbc7a4c1db24d2dd2d1b546e9
Autor:
Nasa Sakamoto, Katsuhiko Gato
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 79, Iss 10, Pp 920-922 (2023)
Quabodepistat [(5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-3,4-dihydroquinolin-2(1H)-one); C21H20ClF3N2O4] and 2,5-dihydroxybenzoic acid (2,5DHBA; C7H6O4) were successfully co-crystallized. Given the sma
Externí odkaz:
https://doaj.org/article/3048a425765a46c5b8a25ee11de7ba09
Publikováno v:
IUCrJ, Vol 10, Iss 4, Pp 430-436 (2023)
In this work, a novel crystal growth method termed suspended drop crystallization has been developed. Unlike traditional methods, this technique involves mixing protein and precipitant directly on an electron microscopy grid without any additional su
Externí odkaz:
https://doaj.org/article/68984af222c643ccbbc98efd18555d28