Zobrazeno 1 - 10
of 525
pro vyhledávání: '"microbeam radiation-therapy"'
Autor:
Michael Valceski, Elette Engels, Sarah Vogel, Jason Paino, Dylan Potter, Carolyn Hollis, Abass Khochaiche, Micah Barnes, Matthew Cameron, Alice O’Keefe, Kiarn Roughley, Anatoly Rosenfeld, Michael Lerch, Stéphanie Corde, Moeava Tehei
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract DNA damage occurs in all living cells. γ-H2AX imaging by fluorescent microscopy is widely used across disciplines in the analysis of double-strand break (DSB) DNA damage. Here we demonstrate a method for the quantitative analysis of such DB
Externí odkaz:
https://doaj.org/article/5f6c406cc4f841d6acda58190038600a
Autor:
Sarvenaz Keshmiri, Gaëtan Lemaire, Sylvan Brocard, Camille Verry, Yacine Bencheikh, Samy Kefs, Laura Eling, Raphaël Serduc, Jean-François Adam
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 30, Iss , Pp 100565- (2024)
Background and Purpose: Microbeam Radiation Therapy (MRT) aims to deliver higher doses to the target while minimizing radiation damage to healthy tissues using synchrotron x-ray microbeams. Translational MRT research has now started, driven by promis
Externí odkaz:
https://doaj.org/article/7cb4191bf72b42429bf04ab16a411b56
Autor:
Elette Engels, Jason R. Paino, Sarah E. Vogel, Michael Valceski, Abass Khochaiche, Nan Li, Jeremy A. Davis, Alice O’Keefe, Andrew Dipuglia, Matthew Cameron, Micah Barnes, Andrew W. Stevenson, Anatoly Rosenfeld, Michael Lerch, Stéphanie Corde, Moeava Tehei
Publikováno v:
Radiation, Vol 3, Iss 4, Pp 183-202 (2023)
Synchrotron Microbeam Radiation Therapy (MRT) is an innovative technique that spatially segments the synchrotron radiation field for cancer treatment. A microbeam peak dose is often hundreds of times the dose in the valley (the sub-millimeter region
Externí odkaz:
https://doaj.org/article/3ae3e8c988f24431b48b35986efbdfe2
Autor:
Raphael Serduc, Audrey Bouchet
Publikováno v:
Journal of Synchrotron Radiation, Vol 30, Iss 3, Pp 591-595 (2023)
Synchrotron microbeam radiation therapy (MRT) is based on the spatial fractionation of the incident synchrotron beam into arrays of parallel microbeams, typically a few tens of micrometres wide and depositing several hundred Gray. This high dose, hig
Externí odkaz:
https://doaj.org/article/4423d8766f4247f39d6064fa8df64edb
Publikováno v:
Journal of Synchrotron Radiation, Vol 30, Iss 2, Pp 359-367 (2023)
It has been shown lately that gold nanoparticles (AuNPs) and ionizing radiation (IR) have inhibitory effects on cancer cell migration while having promoting effects on normal cells' motility. Also, IR increases cancer cell adhesion with no significan
Externí odkaz:
https://doaj.org/article/0e2f7c144b444f28929efd29d4068355
Autor:
Jeremy Davis, Andrew Dipuglia, Matthew Cameron, Jason Paino, Ashley Cullen, Susanna Guatelli, Marco Petasecca, Anatoly Rosenfeld, Michael Lerch
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 1, Pp 125-137 (2022)
Successful transition of synchrotron-based microbeam radiation therapy (MRT) from pre-clinical animal studies to human trials is dependent upon ensuring that there are sufficient and adequate measures in place for quality assurance purposes. Transmis
Externí odkaz:
https://doaj.org/article/441a7a1250464ab392af847c502d5c97
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Akademický článek
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Autor:
Johanna Winter, Marek Galek, Christoph Matejcek, Jan J. Wilkens, Kurt Aulenbacher, Stephanie E. Combs, Stefan Bartzsch
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 14, Iss , Pp 74-81 (2020)
Background and purpose: Microbeam radiotherapy (MRT) is a preclinical concept in radiation oncology with arrays of alternating micrometer-wide high-dose peaks and low-dose valleys. Experiments demonstrated a superior normal tissue sparing at similar
Externí odkaz:
https://doaj.org/article/2af8f29c5b874c5285421cbcc97ff2ed