Zobrazeno 1 - 10
of 106
pro vyhledávání: '"microRNA-17"'
Autor:
Lei Yang, Hong Du, Xuejing Zhang, Bulang Gao, Dongliang Zhang, Zongrong Qiao, Xianhui Su, Tong Bao, Siqin Han
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Circular RNAs (circRNAs) can act as microRNA (miRNA) sponges, thus regulating gene expression. The role of circRNAs in the process of oxygen-glucose deprivation/reoxygenation (OGD/R) is unclear. Here, we explored the mechanism und
Externí odkaz:
https://doaj.org/article/256ba7e1ffb8429aa17a0ba3d6734201
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 1-13 (2022)
LncRNAs can be transported to tumor cells where they exert regulatory effects by bone marrow mesenchymal stem cells (BMSC)-derived exosomes. Here, we aimed to investigate the functional mechanism of BMSC-derived exosomal lncRNA PTENP1 in the progress
Externí odkaz:
https://doaj.org/article/4cac2e96931e47848c388558fff59743
Autor:
Kai Han, Feng-Wei Wang, Chen-Hui Cao, Han Ling, Jie-Wei Chen, Ri-Xin Chen, Zi-Hao Feng, Jie Luo, Xiao-Han Jin, Jin-Ling Duan, Shu-Man Li, Ning-Fang Ma, Jing-Ping Yun, Xin-Yuan Guan, Zhi-Zhong Pan, Ping Lan, Rui-Hua Xu, Dan Xie
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-18 (2020)
Abstract Background Metastasis causes the vast majority of colorectal carcinoma (CRC)-related deaths. However, little is known about the specific traits and underlying mechanisms of metastasis-initiating cells in primary CRC. And whether or not circu
Externí odkaz:
https://doaj.org/article/380d73f1e2204556af19e4714851a964
Autor:
Eivind Hasvik, Tiril Schjølberg, Daniel Pitz Jacobsen, Anne Julsrud Haugen, Lars Grøvle, Elina Iordanova Schistad, Johannes Gjerstad
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-9 (2019)
Abstract Background Previous studies suggest that regulatory microRNAs (miRs) may modulate neuro-inflammatory processes. The purpose of the present study was to examine the role of miR-17 following intervertebral disc herniation. Methods In a cohort
Externí odkaz:
https://doaj.org/article/ffb1d67c4a324772a661bea20fc39ca1
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 53, Iss 10 (2020)
This study determined the expression of plasminogen activator inhibitor-1 (PAI-1) and microRNA (miR)-17 in a mouse depression model. Forty male mice were divided evenly into control and depression groups. A chronic unpredictable mild stress (CUMS) mo
Externí odkaz:
https://doaj.org/article/4e0cb6d8c8844ef9853f4f4b7f98871e
Publikováno v:
FEBS Open Bio, Vol 8, Iss 9, Pp 1508-1523 (2018)
Integrated studies of accumulated data can be performed to obtain more reliable information and more feasible measures for investigating potential diagnostic biomarkers of gastric cancer (GC) and to explore related molecular mechanisms. This study ai
Externí odkaz:
https://doaj.org/article/1289c0d475034b668fb57658f337f97a
Autor:
Di Chen, Brandon J. Dixon, Desislava M. Doycheva, Bo Li, Yang Zhang, Qin Hu, Yue He, Zongduo Guo, Derek Nowrangi, Jerry Flores, Valery Filippov, John H. Zhang, Jiping Tang
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background The endoplasmic reticulum (ER) is responsible for the control of correct protein folding and protein function which is crucial for cell survival. However, under pathological conditions, such as hypoxia–ischemia (HI), there is an
Externí odkaz:
https://doaj.org/article/35cc4eb655054ed0a3bdcded8756876c
Akademický článek
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Akademický článek
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Autor:
Shan Fu
Publikováno v:
International Journal of Molecular Medicine
Acute lung injury (ALI) is a common lung disease with a high mortality rate, which is characterized by an excessive uncontrolled inflammatory response. MicroRNA (miR)-17 has previously emerged as a novel regulatory molecule of inflammatory response i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8201d10ec3125d5982b574f7796ea9fb
https://doi.org/10.3892/ijmm.2020.4599
https://doi.org/10.3892/ijmm.2020.4599