Zobrazeno 1 - 10
of 3 168
pro vyhledávání: '"microRNA/miRNA"'
Autor:
Charlotte Ling, Magdalena Vavakova, Bilal Ahmad Mir, Johanna Säll, Alexander Perfilyev, Melina Martin, Per-Anders Jansson, Cajsa Davegårdh, Olof Asplund, Ola Hansson, Allan Vaag, Emma Nilsson
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background A large proportion of skeletal muscle insulin resistance in type 2 diabetes (T2D) is caused by environmental factors. Methods By applying multiomics mRNA, microRNA (miRNA), and DNA methylation platforms in biopsies from 20 monozyg
Externí odkaz:
https://doaj.org/article/7246b0eb7bc44c71b1797a70ea93092c
Publikováno v:
BioTechniques, Vol 76, Iss 8, Pp 371-379 (2024)
Methods for sequence-specific microRNA (miRNA) analysis are crucial for miRNA research and guiding nursing strategies. We have devised a colorimetric technique for detecting miRNA using a dumbbell probe-based polymerase/endonuclease assisted chain di
Externí odkaz:
https://doaj.org/article/6d4947c5d7424114ab62ce19bc9944bb
Publikováno v:
Bone & Joint Research, Vol 13, Iss 8, Pp 411-426 (2024)
Aims: This study explored the shared genetic traits and molecular interactions between postmenopausal osteoporosis (POMP) and sarcopenia, both of which substantially degrade elderly health and quality of life. We hypothesized that these motor system
Externí odkaz:
https://doaj.org/article/bc59b144083d42fcb21ae53d5c6c5441
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background A retrotransposon HORT1 in the promoter of the anthocyanin activator gene PeMYB11, microRNA858 (miR858) that targets PeMYB11, and a repressor PeMYBx have been implicated in pigmentation patterning diversity of harlequin Phalaenops
Externí odkaz:
https://doaj.org/article/0420b256e87b4c21ad4d9be2e34dfa63
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Salidroside inhibited the proliferation of cancer cell. Nevertheless, the mechanism has not been completely clarified. The purpose of the study is to explore the mechanisms of salidroside against gastric cancer. To analyze the changes of microRNA (mi
Externí odkaz:
https://doaj.org/article/75ab24a3ccb74ad898582a96c21974d3
Autor:
Rawan Amr Elmasri, Alaa A. Rashwan, Sarah Hany Gaber, Monica Mosaad Rostom, Paraskevi Karousi, Montaser Bellah Yasser, Christos K. Kontos, Rana A. Youness
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 2, Pp 547-559 (2024)
A non-negligible part of our DNA has been proven to be transcribed into non-protein coding RNA and its intricate involvement in several physiological processes has been highly evidenced. The significant biological role of non-coding RNAs (ncRNAs), in
Externí odkaz:
https://doaj.org/article/006b961d5e9949cfa957bf4f6d2dc296
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background This study was designed to investigate the mechanism by which miR-30a-5p mediates cardiomyocyte apoptosis after acute myocardial infarction (AMI) induced by hypoxia/reoxygenation (H/R). Methods Differentially expressed miRNAs were
Externí odkaz:
https://doaj.org/article/aa13dd7aef844144895c47a7b3cf4c5e
Autor:
Richard Taylor, Nikolas Nikolaou
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
In neurons, a diverse range of coding and non-coding RNAs localize to axons, dendrites, and synapses, where they facilitate rapid responses to local needs, such as axon and dendrite extension and branching, synapse formation, and synaptic plasticity.
Externí odkaz:
https://doaj.org/article/d5948f72a1ba40979afe12d98a401ae3
Autor:
Saghar Yousefnia
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Long non-coding RNAs (lncRNAs) are versatile RNAs that regulate various cellular processes, such as gene regulation, by acting as signals, decoys, guides, and scaffolds. A novel recognized lncRNA, LOXL1-antisense RNA 1 (LOXL1-AS1), is dysregulated in
Externí odkaz:
https://doaj.org/article/e168fd2defeb4539986a26337eefd9dc
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder that affects the central nervous system (CNS). Neuroinflammation is a crucial factor in the pathological advancement of PD. PD is characterized by the presence of activated microgli
Externí odkaz:
https://doaj.org/article/a3d8a34c471943fa8d503dfe2cbfa86e