Zobrazeno 1 - 10
of 309
pro vyhledávání: '"miRTarBase"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 4, Pp 511-532 (2022)
The dynamic spectrum of microRNA (miRNA) has grown significantly over the years with its identification and exploration in cancer therapeutics and is currently identified as an important resource for innovative strategies due to its functional behavi
Externí odkaz:
https://doaj.org/article/632ad0051ddc431fb5f06d5003f88eb2
Autor:
Dan Ofer, Michal Linial
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Post-transcriptional regulation in multicellular organisms is mediated by microRNAs. However, the principles that determine if a gene is regulated by miRNAs are poorly understood. Previous works focused mostly on miRNA seed matches and other features
Externí odkaz:
https://doaj.org/article/bf8aaa3f1a164dd89e84e408c5a009f6
Publikováno v:
Network Biology, Vol 10, Iss 1, Pp 1-9 (2020)
Sialic acids and MMPs play critical roles in inflammatory diseases. Furthermore, Interaction between Sialic acid and receptors such as siglecs leads phosphorylation of ITIM domains and promote downstream inhibitory signaling through SHP-1 phosphatase
Externí odkaz:
https://doaj.org/article/8d30fda49ee44510bdf31449b06e82cd
Autor:
Hsi-Yuan Huang, Zhuo Wang, Hsien Da Huang, Jingyue Chang, Yijun Luo, Tzong-Yi Lee, Yun Tang, Jhih-Hua Jhong, Xiaoxuan Cai, Yi-Gang Chen, Tzu Hao Chang, Wenshuo Li, Lantian Yao, Shidong Cui, Feng-Xiang Wei, Jingting Wan, Weiming Chen, Qi Chen
Publikováno v:
Nucleic Acids Research
Circular RNAs (circRNAs), which are single-stranded RNA molecules that have individually formed into a covalently closed continuous loop, act as sponges of microRNAs to regulate transcription and translation. CircRNAs are important molecules in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17438e685be151d53bec17ae82714ba4
https://doi.org/10.1093/nar/gkab1036
https://doi.org/10.1093/nar/gkab1036
Autor:
Guanghan Fan, Xuyong Wei, Shusen Zheng, Haiyang Xie, Chenzhi Zhang, Rongli Wei, Xiao Xu, Zhe-Tuo Qi
Publikováno v:
Hepatobiliary & Pancreatic Diseases International. 20:433-451
Background Nonalcoholic fatty liver disease and its advanced stage, nonalcoholic steatohepatitis (NASH), are the major cause of hepatocellular carcinoma (HCC) and other end-stage liver disease. However, the potential mechanism and therapeutic strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dce6430425428d57c3456db05084c04
https://doi.org/10.1016/j.hbpd.2021.06.001
https://doi.org/10.1016/j.hbpd.2021.06.001
Publikováno v:
Journal of Inflammation Research
Purpose This study aims to identify differentially expressed genes (DEGs) in macrophages exposed to ultra-high-molecular-weight polyethylene (UHMWPE) or vitamin E-blended UHMWPE (VE-UHMWPE) particles, thereby providing potential targets for the treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3521ad5aaf4093125f282f53412c689
https://doi.org/10.2147/jir.s320839
https://doi.org/10.2147/jir.s320839
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5499-5512 (2021)
Cancer Medicine
Cancer Medicine
Background Clear‐cell renal cell carcinoma (ccRCC) is stubborn to traditional chemotherapy and radiation treatment, which makes its clinical management a major challenge. Recently, we have made efforts in understanding the etiology of ccRCC. Increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40e5dfdb774b355263f8a8fdf6c3de4
https://doi.org/10.1002/cam4.4109
https://doi.org/10.1002/cam4.4109
Autor:
Ping-Hong You, Jiang Guo, Ying-Wen Liu, Yong-Bo Chen, Liang-You Tang, Liang Gao, Jin-Dong Zhang
Publikováno v:
BioMed Research International, Vol 2021 (2021)
BioMed Research International
BioMed Research International
Aim. This study is aimed at constructing the competing endogenous RNA (ceRNA) network in chromophobe renal cell carcinoma (ChRCC). Methods. Clinical and RNA sequence profiles of patients with ChRCC, including messenger RNAs (mRNAs), microRNAs (miRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800d1809b9af246678f686694447d498
https://doi.org/10.1155/2021/5589101
https://doi.org/10.1155/2021/5589101
Publikováno v:
Aging (Albany NY)
Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder in women of childbearing age. Recent studies suggest important roles for lncRNAs in PCOS development. Based on the hypothesis that lncRNAs are able to regulate mRNA func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8131b041156ab386e575fa66fadf4ad
https://doi.org/10.18632/aging.202659
https://doi.org/10.18632/aging.202659
Autor:
Jiangbo Wan, Bo Liu
Publikováno v:
Bioengineered, Vol 12, Iss 1, Pp 2592-2602 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Long non-coding RNAs (lncRNAs) were considered to be involved in vascular complications in diabetes mellitus, but still only limited knowledge in this regard has been obtained. Herein, we further explored the roles of lncRNAs and mRNAs in diabetic va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f455bcfbac3d70176b79605aec7b737
https://doaj.org/article/e6ba5f683db44ed4b2fefe5f4a1c2bc5
https://doaj.org/article/e6ba5f683db44ed4b2fefe5f4a1c2bc5