Zobrazeno 1 - 10
of 112
pro vyhledávání: '"miRNA therapy"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
A microRNA is a small, single-stranded, non-coding ribonucleic acid that plays a crucial role in RNA silencing and can regulate gene expression. With the in-depth study of miRNA in development and disease, miRNA has become an attractive target for no
Externí odkaz:
https://doaj.org/article/83a7641f4037475485e64eee0fa15ff0
Autor:
Chiara Papi, Jessica Gasparello, Matteo Zurlo, Lucia Carmela Cosenza, Roberto Gambari, Alessia Finotti
Publikováno v:
Non-Coding RNA, Vol 9, Iss 2, p 29 (2023)
(1) Background: MicroRNAs are involved in the expression of the gene encoding the chloride channel CFTR (Cystic Fibrosis Transmembrane Conductance Regulator); the objective of this short report is to study the effects of the treatment of bronchial ep
Externí odkaz:
https://doaj.org/article/4b1c2c4c6c6049969c434e3cd3914a11
Autor:
Walter J. Lukiw
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/a350a177d0b64f8d8cd38d000c18b33d
Autor:
Zhi-Zhong Deng, Ya-Hui Chen
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 2, p 31 (2023)
Spinal cord injury is a serious and devastating condition. Recently, research into microRNAs (miRNAs) has become increasingly exhaustive and it has been determined that they are closely related to the pathophysiological processes of spinal cord injur
Externí odkaz:
https://doaj.org/article/0c9f08686a9f4e9ba3331b469179f100
Autor:
G. Ian Gallicano, Jiayu Fu, Samiksha Mahapatra, Michael V. R. Sharma, Conor Dillon, Claire Deng, Maliha Zahid
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 871 (2022)
Causes and treatments for heart failure (HF) have been investigated for over a century culminating in data that have led to numerous pharmacological and surgical therapies. Unfortunately, to date, even with the most current treatments, HF remains a p
Externí odkaz:
https://doaj.org/article/4d87087299014bdda1e67f3e139e6f71
Autor:
Elisa Callegari, Lucilla D’Abundo, Paola Guerriero, Carolina Simioni, Bahaeldin K. Elamin, Marta Russo, Alice Cani, Cristian Bassi, Barbara Zagatti, Luciano Giacomelli, Stella Blandamura, Farzaneh Moshiri, Simona Ultimo, Antonio Frassoldati, Giuseppe Altavilla, Laura Gramantieri, Luca Maria Neri, Silvia Sabbioni, Massimo Negrini
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 485-493 (2018)
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. Prognosis is poor, and therapeutic options are limited. MicroRNAs (miRNAs) have emerged as potential therapeutic molecules against cancer. Here, we investig
Externí odkaz:
https://doaj.org/article/4318c2eae7294e60b9b3f85625e0de1e
Autor:
Olga A. Patutina, Svetlana K. Miroshnichenko, Nadezhda L. Mironova, Aleksandra V. Sen’kova, Elena V. Bichenkova, David J. Clarke, Valentin V. Vlassov, Marina A. Zenkova
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Control of the expression of oncogenic small non-coding RNAs, notably microRNAs (miRNAs), is an attractive therapeutic approach. We report a design platform for catalytic knockdown of miRNA targets with artificial, sequence-specific ribonucleases. mi
Externí odkaz:
https://doaj.org/article/f4b56814e4af47f7b059a8be3d18d8f9
Autor:
Olga Patutina, Daria Chiglintseva, Elena Bichenkova, Svetlana Gaponova, Nadezhda Mironova, Valentin Vlassov, Marina Zenkova
Publikováno v:
Molecules, Vol 25, Iss 10, p 2459 (2020)
Irreversible destruction of disease-associated regulatory RNA sequences offers exciting opportunities for safe and powerful therapeutic interventions against human pathophysiology. In 2017, for the first time we introduced miRNAses–miRNA-targeted c
Externí odkaz:
https://doaj.org/article/541a1ba4d2404fb3bbf78b1f9a1ee7a8
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Akademický článek
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