Zobrazeno 1 - 10
of 829
pro vyhledávání: '"miRNA sponge"'
Autor:
Mina Shahpari, MohamadReza Hashemi, Tayebeh Younesirad, Aida Hasanzadeh, Mohammad mahdi Mosanne, Mohamadreza Ahmadifard
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e37089- (2024)
Circular RNAs are noncoding RNAs with circular conformation mainly due to backsplicing event. CircRNAs can potentially impact cell biological processes by interacting with cell signaling pathways. Numerous circRNAs have been found to be aberrantly ex
Externí odkaz:
https://doaj.org/article/fffb83548a2c424baff245cb604b2f0a
Autor:
Hua-yang Fan, Ming-da Zhao, Hong-jie Jiang, Zhen-wei Yu, Yu-jiang Fan, Xin-hua Liang, Ya-ling Tang, Yong Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2748-2760 (2024)
Circular RNAs (circRNAs) are ideal biomarkers of oral squamous cell carcinoma (OSCC) because of their highly stable closed-loop structure, and they can act as microRNA (miRNA) sponges to regulate OSCC progression. By analyzing clinical samples, we id
Externí odkaz:
https://doaj.org/article/bc6c22e2f4734da28b8e2db285502560
CircITGA7 regulates malignant phenotypes in bladder cancer cells via targeting miR‐330‐3p/KLF10 axis
Autor:
Xian‐Xu Yang, Chao Wang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 4, Pp 324-334 (2024)
Abstract Bladder cancer (BCa) is one of the common malignancies. Circular RNAs (circRNAs) play regulatory roles in cancer progression. CircITGA7 is a circRNA generated from several exons of ITGA7. The potential role of circITGA7 in BCa remains unknow
Externí odkaz:
https://doaj.org/article/34c5a69d5a8d42b0857a5eec0a15a584
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract With an estimated one million new cases reported annually, gastric cancer (GC) ranks as the fifth most diagnosed malignancy worldwide. The early detection of GC remains a major challenge, and the prognosis worsens either when patients develo
Externí odkaz:
https://doaj.org/article/2e3b723394f14f19bd80eb0d51d20d54
Autor:
Zaosong Zheng, Xiangbo Zeng, Yuanchao Zhu, Mengxin Leng, Zhiyong Zhang, Qiong Wang, Xiaocen Liu, Siying Zeng, Yongyuan Xiao, Chenxi Hu, Shiyu Pang, Tong Wang, Bihong Xu, Peidan Peng, Fei Li, Wanlong Tan
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Renal cell carcinoma (RCC) is one of the most common malignant tumor worldwide. Metastasis is a leading case of cancer-related deaths of RCC. Circular RNAs (circRNAs), a class of noncoding RNAs, have emerged as important regulator
Externí odkaz:
https://doaj.org/article/8f3dad64b3794290b703a43a82f1d4ff
Autor:
Yu Tian, Meng Zhang, Li-xia Liu, Zi-chao Wang, Bin Liu, Youcai Huang, Xiaoling Wang, Yun-zhi Ling, Furong Wang, Xiaoqiang Feng, Yanyang Tu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related deaths in the world. The development and progression of HCC are closely correlated with the abnormal regulation of non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), lon
Externí odkaz:
https://doaj.org/article/7035cc5e06264a8eac0063a2d762d5d3
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-26 (2023)
Abstract Background Abdominal fat deposition depends on both the proliferation of preadipocytes and their maturation into adipocytes, which is a well-orchestrated multistep process involving many regulatory molecules. Circular RNAs (circRNAs) have em
Externí odkaz:
https://doaj.org/article/7e384ecf911a4249978f49b418137426
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Organ fibrosis can occur in virtually all major organs with relentlessly progressive and irreversible progress, ultimately resulting in organ dysfunction and potentially death. Unfortunately, current clinical treatments cannot halt or revers
Externí odkaz:
https://doaj.org/article/da60e73e030f4af8bf51696b0c485130
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106946- (2023)
Ocular neovascular disease (OND), characterized by the aberrant formation of immature blood vessels, is the leading cause of vision impairment and blindness. It is important to find effective ways to diagnose and treat these diseases. Circular RNA (c
Externí odkaz:
https://doaj.org/article/0f1d00982eb549089c4df24d73dadeb1
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Macrophages (Mφ) are long-lived myeloid cells that can polarize towards the proinflammatory M1 or proresolving M2 phenotype to control diverse biological processes such as inflammation, tissue damage, and regeneration. Noncoding RNA are a class of n
Externí odkaz:
https://doaj.org/article/24a74937c9374b4c9f97e777bb2b7a85