Bone marrow mesenchymal stem cells expressing Neat-1, Hotair-1, miR-21, miR-644, and miR-144 subsided cyclophosphamide-induced ovarian insufficiency by remodeling the IGF-1–kisspeptin system, ovarian apoptosis, and angiogenesis

Autor: Amany I. Ahmed, Mohamed F. Dowidar, Asmaa F. Negm, Hussein Abdellatif, Asma Alanazi, Mohammed Alassiri, Walaa Samy, Dina Mohamed Mekawy, Eman M. A. Abdelghany, Nesma I. El-Naseery, Mohamed A. Ibrahem, Emad Ali Albadawi, Wed Salah, Mamdouh Eldesoqui, Emil Tîrziu, Iulia Maria Bucur, Ahmed Hamed Arisha, Tarek Khamis

Publikováno v: Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-21 (2024)

Abstract Ovarian insufficiency is one of the common reproductive disorders affecting women with limited therapeutic aids. Mesenchymal stem cells have been investigated in such disorders before yet, the exact mechanism of MSCs in ovarian regeneration

Externí odkaz: https://doaj.org/article/12264e85efd9421e80924edd94522be2

Correction: Bone marrow mesenchymal stem cells expressing Neat-1, Hotair-1, miR-21, miR-644, and miR-144 subsided cyclophosphamide-induced ovarian insufficiency by remodeling the IGF-1-kisspeptin system, ovarian apoptosis, and angiogenesis.

Autor: Ahmed AI; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt., Dowidar MF; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt., Negm AF; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt., Abdellatif H; Department of Human and Clinical Anatomy, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman.; Human Anatomy and Embryology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Alanazi A; Collage of Medicine, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia., Alassiri M; King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.; Department of Basic Medical Sciences, College of Science and Health Professions (COSHP), King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia., Samy W; Medical Biochemistry Department, Faculty of Medicine, Zagazig University, Zagazig, 44519, Egypt., Mekawy DM; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Badr University in Cairo, Badr City, 11829, Egypt., Abdelghany EMA; Human Anatomy and Embryology Department, Faculty of Medicine, Zagazig University, Zagazig, 44519, Egypt., El-Naseery NI; Department of Histology and Cytology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt., Ibrahem MA; Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, 44519, Egypt., Albadawi EA; Department of Anatomy, College of Medicine, Taibah University, Medina, Saudi Arabia., Salah W; Department of Anatomy, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia., Eldesoqui M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O.Box 71666, 11597, Riyadh, Saudi Arabia.; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt., Tîrziu E; Department of Animal Production and Veterinary Public Health, Faculty of Veterinary Medicine, University of Life Sciences, 'King Mihai I' From Timisoara [ULST], Aradului St. 119, 300645, Timisoara, Romania., Bucur IM; Department of Animal Production and Veterinary Public Health, Faculty of Veterinary Medicine, University of Life Sciences, 'King Mihai I' From Timisoara [ULST], Aradului St. 119, 300645, Timisoara, Romania. Iulia.bucur@usvt.ro., Arisha AH; Department of Animal Physiology and Biochemistry, Faculty of Veterinary Medicine, Badr University in Cairo, Badr City, 11829, Egypt. vetahmedhamed@zu.edu.eg.; Department of Physiology and Laboratory of Biotechnology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt. vetahmedhamed@zu.edu.eg., Khamis T; Department of Pharmacology and Laboratory of Biotechnology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt. t.khamis@vet.zu.edu.eg.

Publikováno v: Journal of ovarian research [J Ovarian Res] 2024 Nov 29; Vol. 17 (1), pp. 239. Date of Electronic Publication: 2024 Nov 29.

Circular RNA circPFKP suppresses the proliferation and metastasis of gastric cancer cell via sponging miR-644 and regulating ADAMTSL5 expression

Autor: Shuai, Kong, Shubo, Tian, Zhu, Wang, Yulong, Shi, Jizhun, Zhang, Hongqing, Zhuo

Publikováno v: Bioengineered. 13:12326-12337

The treatment of gastric cancer (GC) is extremely challenging; however, the specific pathogenesis of GC remains unclear. Circular RNAs (CircRNAs) are non-coding RNAs that can regulate gene expression both transcriptionally and post-transcriptionally.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7444ad406f4b04e033a3d5aa721d6951
https://doi.org/10.1080/21655979.2022.2073001

Tumor Suppressor MicroRNAs in Clinical and Preclinical Trials for Neurological Disorders.

Autor: Lui, Austin¹ (AUTHOR) alui@ucdavis.edu, Do, Timothy¹ (AUTHOR) vkailash2@student.touro.edu, Alzayat, Omar¹ (AUTHOR), Yu, Nina¹ (AUTHOR), Phyu, Su² (AUTHOR), Santuya, Hillary Joy¹ (AUTHOR), Liang, Benjamin¹ (AUTHOR), Kailash, Vidur¹ (AUTHOR), Liu, Dewey¹ (AUTHOR), Inslicht, Sabra S.^3,4 (AUTHOR), Shahlaie, Kiarash⁵ (AUTHOR), Liu, DaZhi^1,6 (AUTHOR) dzliu@ucdavis.edu

Publikováno v: Pharmaceuticals (14248247). Apr2024, Vol. 17 Issue 4, p426. 22p.

Potential Implications of miRNAs in the Pathogenesis, Diagnosis, and Therapeutics of Alzheimer's Disease.

Autor: Wang, Long¹ (AUTHOR), Shui, Xindong¹ (AUTHOR), Diao, Yuelin¹ (AUTHOR) wanglong@fjmu.edu.cn, Chen, Duoting¹ (AUTHOR), Zhou, Ying¹ (AUTHOR) zhouying@fjmu.edu.cn, Lee, Tae Ho¹ (AUTHOR) zhouying@fjmu.edu.cn

Publikováno v: International Journal of Molecular Sciences. Nov2023, Vol. 24 Issue 22, p16259. 24p.