Zobrazeno 1 - 10
of 458
pro vyhledávání: '"miR-200b"'
Autor:
Min Jiang, Feng Qi, Kai Zhang, Xiaofei Zhang, Jingjing Ma, Suhua Xia, Longbang Chen, Zhengyuan Yu, Jing Chen, Dongqin Chen
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background Long non-coding RNAs (lncRNAs) are implicated in the development of multiple cancers. In our previous study, we demonstrated that HDAC1/4-mediated silencing of microRNA-200b (miR-200b) enhances docetaxel (DTX)-resistance of human
Externí odkaz:
https://doaj.org/article/f4c0f938d069486081dc1af8147ed008
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 37, Iss 7, Pp 572-582 (2021)
Abstract Nobiletin is a polymethoxylated flavone present in citrus fruits, which has been reported to have inhibitory effects on tumorigenesis of cancers. However, the biological function of nobiletin in breast cancer (BC) is largely unknown. To inve
Externí odkaz:
https://doaj.org/article/a81fa21035544d74ae95730040c443ba
Publikováno v:
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Background Ovarian cancer is the seventh most common cancer in women and the second most reason of gynecologic cancer-related death. Growing evidence showed that exosomal miRNA plays a crucial role in the progression of ovarian cancer. Metho
Externí odkaz:
https://doaj.org/article/faf59de3119341a5a6e7d6d8cbc49edf
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Human trophoblast stem cells (TSCs) have been confirmed to play a cardioprotective role in heart failure. However, whether trophoblast stem cell-derived exosomes (TSC-Exos) can protect cardiomyocytes from doxorubicin (Dox)-induced injury rem
Externí odkaz:
https://doaj.org/article/854bb467a17741d49254a9614e4f61d8
Autor:
Chaosheng Yu, Fang Chen, Xiaoqi Wang, Zhimou Cai, Mengxue Yang, Qingwen Zhong, Jialian Feng, Junzheng Li, Congxiang Shen, Zhong Wen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-13 (2020)
Abstract Background Recurrence and distant metastasis are still the main factors leading to treatment failure for malignant tumors including nasopharyngeal carcinoma (NPC). Therefore, elucidating the molecular mechanisms underlying nasopharyngeal car
Externí odkaz:
https://doaj.org/article/d42181fb6b064939bcac5b76ae7a9d1d
Publikováno v:
Di-san junyi daxue xuebao, Vol 42, Iss 4, Pp 407-413 (2020)
Objective To investigate the role of microRNA-200b (miR-200b) in corneal neovascularization (CNV) in rats and explore the possible mechanisms. Methods Twenty-four female SD rats were subjected to corneal suture to induce CNV in one eye, with the othe
Externí odkaz:
https://doaj.org/article/595e7210b5b84f2ba738e35c8fe0d995
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 48, Iss 1, Pp 656-663 (2020)
Smoking is an important factor in the pathogenesis of chronic obstructive pulmonary disease (COPD), which is commonly characterised by cellular senescence and inflammation. Recently, miR-200b has emerged as an important target to cure lung disease; h
Externí odkaz:
https://doaj.org/article/c21cfc20ef334cb2a9e65affe2d8b44f
Autor:
Yin Zhang, Qinge Wang, Yuping Xu, Jing Sun, Yanbo Ding, Li Wang, Bingfang Chen, Kewen Sun, Jianping Chen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Benign esophageal strictures (BESs) frequently results from esophageal fibrosis. The transformation of fibroblasts into fibrocyte is an important cause of fibrosis. The treatment of fibrosis is challenging. Some previous studies have indicated the an
Externí odkaz:
https://doaj.org/article/fbdc017864a14ba6a01a4a4d0f2599cd
Autor:
Shasha Ren, Jiuzhou Liu, Yun Feng, Zhenyu Li, Liang He, Leilei Li, Xiaozhong Cao, Zhenghua Wang, Yanwu Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Background Hypoxia is a key feature of breast cancer, which affects cancer development, metastasis and metabolism. Previous studies suggested that circular RNAs (circRNAs) could participate in cancer progression and hypoxia regulation. This
Externí odkaz:
https://doaj.org/article/1989987b87f5413284072cd2cebfc26a
Autor:
Ruxu Gao, Naiwen Zhang, Jianyu Yang, Yuyan Zhu, Zhe Zhang, Jianfeng Wang, Xiaolong Xu, Zeliang Li, Xiankui Liu, Zhenhua Li, Jun Li, Chuize Kong, Jianbin Bi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background The effect of competing endogenous RNA (ceRNA) can regulate gene expression by competitively binding microRNAs. Fascin-1 (FSCN1) plays an important role in the regulation of cellular migration and invasion during tumor progression
Externí odkaz:
https://doaj.org/article/95f6303b9b0643fb8a9c4acb9286c895