The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

Autor: Katharina Hutter, Thomas Rülicke, Tamas G. Szabo, Lill Andersen, Andreas Villunger, Sebastian Herzog

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

MicroRNAs are small non-coding RNAs that have emerged as post-transcriptional regulators involved in development and function of different types of immune cells, and aberrant miRNA expression has often been linked to cancer. One prominent miRNA famil

Externí odkaz: https://doaj.org/article/d7203d1cea344819b421c719e24a2b13

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Functionally conserved non-coding regulators of cardiomyocyte proliferation and regeneration in mouse and human

Autor: Claire Morgan, Michael D. Schneider, Sian E. Harding, Peter O'Gara, Josef M. Penninger, Pascal Gellert, Leonardo Bottolo, Prashant K. Srivastava, Bonnie Razzaghi, Bernhard J. Haubner, Melissa J. Collins, Timothy J. Aitman, Marta Abreu Paiva, Martyna Adamowicz, Priyanka Raina, Laurence Game, Michela Noseda

Publikováno v: Adamowicz-Brice, M, Morgan, C, Haubner, B J, Noseda, M, Collins, M J, Abreu Paiva, M, Srivastava, P K, Gellert, P, Razzaghi, B, O'Gara, P, Raina, P, Game, L, Bottolo, L, Schneider, M D, Harding, S E, Penninger, J & Aitman, T 2018, ' Functionally conserved non-coding regulators of cardiomyocyte proliferation and regeneration in mouse and human ', Circulation: Cardiovascular Genetics, vol. 11, no. 2 . https://doi.org/10.1161/CIRCGEN.117.001805

Background: The adult mammalian heart has little regenerative capacity after myocardial infarction (MI), whereas neonatal mouse heart regenerates without scarring or dysfunction. However, the underlying pathways are poorly defined. We sought to deriv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3650ddca0d327697dfaa772548a7204c
https://www.pure.ed.ac.uk/ws/files/53398381/Adamowicz_et_al_.pdf

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

Autor: Louise M Burrell, Indrajeetsinh Rana, Claire L. Curl, Scott C. Ritchie, Pasi Soininen, Johannes Kettunen, Piyush M Srivastava, Mary E. Wlodek, Sean G. Byars, Markus Perola, Stuart P. Berzins, Jason Kelly, Olli T. Raitakari, Francine Z. Marques, Paul Lewandowski, Bryan Wai, Veikko Salomaa, Mika Kähönen, Yosuke Minoda, Jimmy D. Bell, Stephen B. Harrap, Emma Raitoharju, Priscilla R. Prestes, Saku Ruohonen, Fadi J. Charchar, Aki S. Havulinna, Peter Würtz, Antti J. Kangas, Terho Lehtimäki, Scott A. Booth, Lea M.D. Delbridge, Michael Inouye, Sheila K Patel, Maree A McGlynn, Mika Ala-Korpela

Publikováno v: Marques, F Z, Prestes, P R, Byars, S G, Ritchie, S C, Würtz, P, Patel, S K, Booth, S A, Rana, I, Minoda, Y, Berzins, S P, Curl, C L, Bell, J R, Wai, B, Srivastava, P M, Kangas, A J, Soininen, P, Ruohonen, S, Kähönen, M, Lehtimäki, T, Raitoharju, E, Havulinna, A, Perola, M, Raitakari, O, Salomaa, V, Ala-Korpela, M, Kettunen, J, McGlynn, M, Kelly, J, Wlodek, M E, Lewandowski, P A, Delbridge, L M, Burrell, L M, Inouye, M, Harrap, S B & Charchar, F J 2017, ' Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure ', Journal of the American Heart Association, vol. 6, no. 6, e005971 . https://doi.org/10.1161/JAHA.117.005971
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Background Cardiac hypertrophy increases the risk of developing heart failure and cardiovascular death. The neutrophil inflammatory protein, lipocalin‐2 (LCN2/NGAL), is elevated in certain forms of cardiac hypertrophy and acute heart failure. Howev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d103192332afee719e450d9adc746d
http://hdl.handle.net/10138/203757

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