Zobrazeno 1 - 10
of 537
pro vyhledávání: '"miR-148a"'
Autor:
Xuchang Zhou, Hong Cao, Tao Liao, Weizhong Hua, Ruobing Zhao, Dongxue Wang, Huili Deng, Yajing Yang, ShengYao Liu, Guoxin Ni
Publikováno v:
Non-coding RNA Research, Vol 10, Iss , Pp 163-176 (2025)
Objective: Investigating whether mechanosensitive lncRNA H19 can directly target miR-148a to alleviate cartilage damage in post-traumatic osteoarthritis (PTOA). Methods: Thirty-two female rats were randomly divided into four groups: Sham-operated gro
Externí odkaz:
https://doaj.org/article/ce573f8eb51f49a6a076fbe46bf0d686
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-11 (2023)
Abstract MicroRNAs are involved in the immune systems of host animals and play essential roles in several immune-related pathways. In the current study, we investigated the systemic biological function of the chicken miRNA gga-miR-148a-3p on immune r
Externí odkaz:
https://doaj.org/article/b2fad73ff88b4953963c5aaa39804574
Autor:
O.E. Abaturov, A.O. Tovarnytska
Publikováno v:
Zdorovʹe Rebenka, Vol 18, Iss 1, Pp 32-39 (2023)
Background. Breast milk (BM) is an optimal nutritional product for newborns and a source of exogenous microRNAs (miR). MiR-148a is one of the most highly expressed miR of BM. Currently, there is a lack of data on the miR-148a effect on the developmen
Externí odkaz:
https://doaj.org/article/1b7632b0d45141a584a409b62d912346
Autor:
Priyanka Madaan, Uttam Sharma, Nipanshi Tyagi, Balvinder Kaur Brar, Shivani Bansal, Hemant Rituraj Kushwaha, Harmanpreet Singh Kapoor, Aklank Jain, Manju Jain
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Psoriasis is a chronic inflammatory skin disease with keratinocyte hyperproliferation and T cells as key mediators of lesional and systemic inflammatory changes. To date, no suitable differential biomarkers are available for the disease diagnosis. Mo
Externí odkaz:
https://doaj.org/article/3b43bfa13f7a4b1182b28bb00434fdd6
Autor:
Siyuan Tian, Xia Zhou, Miao Zhang, Lina Cui, Bo Li, Yansheng Liu, Rui Su, Keshuai Sun, Yinan Hu, Fangfang Yang, Guoyun Xuan, Shuoyi Ma, Xiaohong Zheng, Xinmin Zhou, Changcun Guo, Yulong Shang, Jingbo Wang, Ying Han
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Despite emerging evidence on the therapeutic potential of mesenchymal stem cells (MSCs) for liver fibrosis, the underlying mechanisms remain unclear. At present, MSC-derived exosomes (MSC-EXOs) are widely accepted as crucial messe
Externí odkaz:
https://doaj.org/article/f737994c3a15412893e39020386110de
Autor:
Takeshi Chiba, Aya Kooka, Kiyoko Kowatari, Megumi Yoshizawa, Naoko Chiba, Akira Takaguri, Yoshiyuki Fukushi, Fuminori Hongo, Hideki Sato, Shinichiro Wada
Publikováno v:
International Breastfeeding Journal, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Milk-derived microRNAs (miRNAs), including hsa-miR-148a-3p (miR-148a) and hsa-miR-125b-5p (miR-125b), have been shown to be beneficial to the gastrointestinal function in infants. Here, we investigated their expression during lact
Externí odkaz:
https://doaj.org/article/ab19b35de087404582ce6f59ba34940a
Akademický článek
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Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background MCM3AP-AS1 is a recently characterized lncRNA playing an oncogenic role in several cancers. However, its role in lung cancer remains unknown. Here, we aimed to explore the functions of MCM3AP-AS1 in small cell lung cancer (SCLC) a
Externí odkaz:
https://doaj.org/article/01b54ec498d74bdab2d8329daf638f27
Autor:
Hans Martin Singh, Mathias Felix Leber, Sascha Bossow, Christine E. Engeland, Jan Dessila, Christian Grossardt, Karim Zaoui, John C. Bell, Dirk Jäger, Christof von Kalle, Guy Ungerechts
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss , Pp 340-355 (2021)
Advanced pancreatic cancer is characterized by few treatment options and poor outcomes. Oncolytic virotherapy and chemotherapy involve complementary pharmacodynamics and could synergize to improve therapeutic efficacy. Likewise, multimodality treatme
Externí odkaz:
https://doaj.org/article/95b9c48283a54a47bc599fb72e9ab78d
Autor:
Fengge Ma, Yating Zhan, Rocío Bartolomé-Cabrero, Wei Ying, Masahide Asano, Zhe Huang, Changchun Xiao, Alicia González-Martín
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A microRNA (miRNA) often regulates the expression of hundreds of target genes. A fundamental question in the field of miRNA research is whether a miRNA exerts its biological function through regulating a small number of key targets or through small c
Externí odkaz:
https://doaj.org/article/ecfc024c2cf4473db512b45cf640eea7