Zobrazeno 1 - 10
of 2 787
pro vyhledávání: '"miR-146a"'
Autor:
Keerthana Chithanathan, Monika Jürgenson, Katrina Ducena, Anu Remm, Kalev Kask, Ana Rebane, Li Tian, Alexander Zharkovsky
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background MicroRNAs (miRNAs) play crucial roles in regulating inflammation and cellular senescence. Among them, miR-146a has emerged as a key modulator of inflammation, but its role in obesity-induced senescence remains unexplored. This stu
Externí odkaz:
https://doaj.org/article/ed07ab84635d4886b4a291dc8a041d30
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background and objectives Behçet’s disease (BD) is an ongoing systemic vasculitis with mouth and genital ulceration and eye, skin, and systemic affection. It has considerable morbidity and mortality, and a high incidence and a higher male
Externí odkaz:
https://doaj.org/article/afd345974ccd4d6ab73863615633bc67
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background Sepsis-induced myocardial injury (SIMI) is a severe complication of sepsis, contributing significantly to mortality. Mitochondrial dysfunction and dysregulated autophagy are implicated in SIMI pathogenesis. Long non-coding RNA MAL
Externí odkaz:
https://doaj.org/article/bb3ba06f97784a29876e69241482abc5
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 10, Pp 1249-1254 (2024)
Objective·To investigate the expression of miR-146a in peripheral blood CD4+ T lymphocytes of patients with rheumatoid arthritis (RA) and its correlation with inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6).
Externí odkaz:
https://doaj.org/article/589f1eeb6daf44bbaae3681cf7cd1c57
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Small extracellular vesicles (sEVs) have the ability to transfer genetic material between cells, but their role in mediating HBV infection and regulating M1 macrophages to promote immune evasion remains unclear. In this study, we utilized PM
Externí odkaz:
https://doaj.org/article/f87a085529ea456083fd96ea64f128aa
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 17, Pp 2747-2760 (2024)
Hua Ji,1,* YaTing Lu,1,* Gui Liu,2 Xiaotong Zhao,1 Murong Xu,1 Mingwei Chen1 1Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei City, Anhui Province, People’s Republic of China; 2Department of End
Externí odkaz:
https://doaj.org/article/9c94c5582b854cf193fde219d6e623c3
Autor:
Dalia Saad ElFeky, Noha Mohamed Omar, Olfat Gamil Shaker, Walaa Abdelrahman, Tamer A. Gheita, Mona Gamal Nada
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionLupus nephritis (LN) is one of the most prevalent severe organ manifestations of systemic lupus erythematosus (SLE), impacting 70% of SLE patients. MicroRNAs (miRNAs), are small non-coding RNA molecules which influence the expression of a
Externí odkaz:
https://doaj.org/article/e40320c430784e9a828576d8d99dc948
Autor:
HaiFeng Liu, Hongchuan Deng, Haocheng Huang, Jiahui Cao, Xinmiao Wang, Ziyao Zhou, Zhijun Zhong, Dechun Chen, Guangneng Peng
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionThe most common factor leading to renal failure or death is renal IR (ischemia-reperfusion). Studies have shown that mesenchymal stem cells (MSCs) and their exosomes have potential therapeutic effects for IR injury by inhibiting M1 macrop
Externí odkaz:
https://doaj.org/article/6b401db5b4874d30ac7d551cbc1857eb
Autor:
Ruiqi Han, Huimin Zhong, Yang Zhang, Huan Yu, Yumeng Zhang, Shouyue Huang, Zijian Yang, Yisheng Zhong
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Purpose To explore the impact of microRNA 146a (miR-146a) and the underlying mechanisms in profibrotic changes following glaucoma filtering surgery (GFS) in rats and stimulation by transforming growth factor (TGF)-β1 in rat Tenon’s capsul
Externí odkaz:
https://doaj.org/article/1e1a33f7ef2244a58f106919c449b8f2
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Ex vivo drug screening is a potentially powerful tool for the future of cancer care, but the accuracy of results is contingent on the culture model. Both monolayer (2D) and spheroid (3D) culture systems offer advantages, but given the differ
Externí odkaz:
https://doaj.org/article/81626952cd494d1baa82e7bbce47b17c