Zobrazeno 1 - 10
of 1 006
pro vyhledávání: '"miR-143"'
Autor:
Ming-Yi Lu, Pei-Ling Hsieh, Shih-Chi Chao, Chih-Yuan Fang, Yoichi Ohiro, Yi-Wen Liao, Cheng-Chia Yu, Min-Te Chang
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 3, Pp 1416-1425 (2024)
Background/purpose: Persistent activation of myofibroblasts is attributed to various dysregulated biological events conferring multiple types of fibrosis diseases, including oral submucous fibrosis (OSF). Although the significance of non-coding RNAs
Externí odkaz:
https://doaj.org/article/d0451fcb97e945d883d1d1c1fcd42e60
Autor:
E. N. Voropaeva, T. I. Pospelova, A. M. Nesterets, M. I. Churkina, O. V. Berezina, V. N. Maksimov
Publikováno v:
Сибирский научный медицинский журнал, Vol 43, Iss 5, Pp 169-175 (2023)
The study of DNA methylation status in malignant lymphomas is a new field of research in oncohematology. The aim of this study was to quantify the level of methylation of the MIR-143 gene in the tumor tissue of patients with diffuse large B-cell lymp
Externí odkaz:
https://doaj.org/article/96e6255394d843d59b1f12e0684d684b
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 954 (2024)
Cardiac mesoderm enhancer-associated non-coding RNA (CARMN), an evolutionarily conserved long non-coding RNA (lncRNA), serves as the host gene for the miR143/145 cluster. It plays a crucial role in cardiovascular cell differentiation and the maintena
Externí odkaz:
https://doaj.org/article/d217307f810948e98b1c9047293f446c
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 3, Pp 134-143 (2023)
The purpose of the study was to present up-to-date data on the regulation of expression, function in normal tissues and multidirectional activity in the oncogenesis of miR-143/145 microRNAs cluster, as well as to evaluate the possibilities and limita
Externí odkaz:
https://doaj.org/article/00a681db88dd45c6b7e6921ceddb5f1a
Autor:
Daniele Lavacchi, Simone Polvani, Antonio Taddei, Federico Scolari, Luca Messerini, Enrico Caliman, Luca Moraldi, Alessia Guidolin, Gian Luca Grazi, Andrea Galli, Serena Pillozzi, Lorenzo Antonuzzo
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionPancreatic adenocarcinoma (PC) is one of the most lethal malignancies; even after resection the patients’ 5-year disease-free survival (DFS) is lower than 26%. The genetic mutational landscape of PC is dominated by activating KRAS mutat
Externí odkaz:
https://doaj.org/article/efcffb8b6c89433990e68a34e3066f61
Autor:
Jun Arima, Kohei Taniguchi, Nobuhiko Sugito, Kazuki Heishima, Yoshihisa Tokumaru, Yosuke Inomata, Kazumasa Komura, Tomohito Tanaka, Masa-Aki Shibata, Sang-Woong Lee, Yukihiro Akao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102079- (2023)
Replenishing tumor-suppressor miRNAs (TS-miRNAs) is a potential next-generation nucleic acid–based therapeutic approach. Establishing an effective miRNA delivery system is essential to successful TS-miRNA therapy. To overcome vulnerability to RNA n
Externí odkaz:
https://doaj.org/article/7b66e61b743a46dbb834022e28a5558d
Publikováno v:
Boğaziçi Tıp Dergisi, Vol 10, Iss 1, Pp 19-25 (2023)
INTRODUCTION: Brain damage in the early-period after subarachnoid hemorrhage (SAH) is a significant cause of mortality; however, cell proliferation, apoptosis, and inflammatory cascades play roles in preventing. This study aimed to determine the effe
Externí odkaz:
https://doaj.org/article/ad59e94c73104598b8a644b449042868
Autor:
Archana Shrestha, Behnaz Lahooti, A. K. M. Nawshad Hossian, Mahboubeh Madadi, Constantinos M. Mikelis, George Mattheolabakis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4432 (2024)
The mainstays of lung cancer pathogenesis are cell cycle progression dysregulation, impaired apoptosis, and unregulated cell proliferation. While individual microRNA (miR) targeting or delivering is a promising approach that has been extensively stud
Externí odkaz:
https://doaj.org/article/5678caba4dca4c77804a1d6c698a485f
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionCirculating microRNAs are promising biomarkers for multiple sclerosis (MS). Our aim was to correlate serum microRNA levels with various magnetic resonance imaging (MRI) parameters.MethodsWe recruited 50 MS patients and measured cervical s
Externí odkaz:
https://doaj.org/article/85ad228fdddf45b38b3e1ebfeb055b5b
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-20 (2022)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer and is susceptible to develop gemcitabine (GEM) resistance. Decreased expression of human equilibrative nucleoside transporter 1 (hENT1) accompanied by
Externí odkaz:
https://doaj.org/article/0512b8f0a3da405696e4498be5410a03