Zobrazeno 1 - 10
of 318
pro vyhledávání: '"miR-140"'
Autor:
Jack B. Roberts, Olivia L.G. Boldvig, Guillaume Aubourg, S. Tanishq Kanchenapally, David J. Deehan, Sarah J. Rice, John Loughlin
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background Transitioning from a genetic association signal to an effector gene and a targetable molecular mechanism requires the application of functional fine-mapping tools such as reporter assays and genome editing. In this report, we unde
Externí odkaz:
https://doaj.org/article/9c31b31140bb46b0badb848d45713eab
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 700-705 (2022)
Background FAM230B serves as an oncogenic lncRNA in both gastric cancer and papillary thyroid cancer, while its role in acute myeloid leukemia (AML) is unclear. We predicted that FAM230B could be a target of miR-140, a well-characterized tumor suppre
Externí odkaz:
https://doaj.org/article/8d089fbd6c30472780119b7a3506f020
Autor:
Shuang-feng CHU, Tian-qi ZHAO, Abdelaziz Adam Idriss ARBAB, Yi YANG, Zhi CHEN, Zhang-ping YANG
Publikováno v:
Journal of Integrative Agriculture, Vol 21, Iss 10, Pp 3004-3016 (2022)
Fat is an indispensable nutrient and basic metabolite for sustaining life, and milk is particularly rich in fatty acids, including a variety of saturated and unsaturated fatty acids. MicroRNA (miRNA) and mRNA play an important role in the regulation
Externí odkaz:
https://doaj.org/article/6b251e097c0b4f2eb8d820c53a4c2a7e
Autor:
Mingyue Xia, Shuyan Wang, Yannan Qi, Kaili Long, Enjie Li, Lingfeng He, Feiyan Pan, Zhigang Guo, Zhigang Hu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/8a1b2119daf94e70b3ef3b72edf88983
Akademický článek
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Publikováno v:
Jichu yixue yu linchuang, Vol 42, Iss 9, Pp 1344-1349 (2022)
Objective To evaluate the effect of miR-140 on the sensitivity of imatinib(IM)-resistant chronic myeloid leukemia (CML) cell strain KBM5R to IM and potential underlying mechanism. Methods The expression level of miR-140 and Bcl-2 in CML cells KBM5 an
Externí odkaz:
https://doaj.org/article/cb45a36f84e84c00a556a30f7eb48508
Autor:
Shujie Li, Yue Xie, Wei Zhou, Qian Zhou, Dan Tao, Haonan Yang, Kaijin Mao, Shi Li, Jinyan Lei, Yongzhong Wu, Ying Wang
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16868- (2023)
Objective: To investigate the effect of MALAT1 on the modulating the radiosensitivity of lung adenocarcinoma, through regulation of the expression of the miR-140/PD-L1 axis. Methods: The online databases UALCAN and dbDEMC were searched for the MALAT1
Externí odkaz:
https://doaj.org/article/5ffd5d0244f94633b3dc195aa57c9b1d
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Background Osteoarthritis (OA) is a common degenerative joint disease, and chondrocyte extracellular matrix (ECM) degradation is one vital pathological feature of OA. Long noncoding RNA (lncRNA), a new kind of gene regulator, plays an import
Externí odkaz:
https://doaj.org/article/c813674b9d70431bacc8fef7c8a6d120
Autor:
Mingyue Xia, Shuyan Wang, Yannan Qi, Kaili Long, Enjie Li, Lingfeng He, Feiyan Pan, Zhigang Guo, Zhigang Hu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The expression of O-GlcNAc transferase (OGT) and its catalytic product, O-GlcNAcylation (O-GlcNAc), are elevated in many types of cancers, including prostate cancer (PC). Inhibition of OGT serves as a potential strategy for PC treatment alone or comb
Externí odkaz:
https://doaj.org/article/de42b44a8c9c4483870087e1aad8e21a
Autor:
Josef Horak, Alexandra Dolnikova, Ozge Cumaogullari, Andrea Cumova, Nazila Navvabi, Ludmila Vodickova, Miroslav Levy, Michaela Schneiderova, Vaclav Liska, Ladislav Andera, Pavel Vodicka, Alena Opattova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cancer therapy failure is a fundamental challenge in cancer treatment. One of the most common reasons for therapy failure is the development of acquired resistance of cancer cells. DNA-damaging agents are frequently used in first-line chemotherapy re
Externí odkaz:
https://doaj.org/article/3522c5a78afe4cca8e6b702e06abe405