Zobrazeno 1 - 10
of 737
pro vyhledávání: '"miR‐17‐5p"'
Autor:
Maryam Mohammad-Sadeghipour, Mohammad Hadi Nematollahi, Hassan Ahmadinia, Mohammad Reza Hajizadeh, Mehdi Mahmoodi
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 5, Pp 606-621 (2024)
Background and purpose: This study investigated modulating the G protein-coupled estrogen receptor (GPER) on the IRElα/TXNIP pathway and its role in drug resistance in MDA-MB231 cells. Experimental approach: To determine the optimal concentrations o
Externí odkaz:
https://doaj.org/article/a5a44b0e0c494b0aa67c886b131b425d
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Lung adenocarcinoma is the most common type of lung cancer, accounting for approximately 40% of all lung cancer cases, and has the highest incidence among lung cancer subtypes. Recent studies have suggested that long non-coding RNAs (lncRN
Externí odkaz:
https://doaj.org/article/e9ef9bd3a26f47c69708a304f406b336
Akademický článek
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Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The incidence of gastric cancer ranks the first among digestive tract tumors in China. However, there are no specific symptoms in the early stage of the tumor and the diagnosis process is complex, so more effective detection metho
Externí odkaz:
https://doaj.org/article/873405375eb7414691e54b9e22538444
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Acute myeloid leukemia (AML), characterized by the abnormal accumulation of immature marrow cells in the bone marrow, is a malignant tumor of the blood system. Currently, the pathogenesis of AML is not yet clear. Therefore, this study aims t
Externí odkaz:
https://doaj.org/article/b1ccfa254b9a44e59008c027b132e52b
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 114-128 (2023)
Triple-negative breast cancer (TNBC) is a subtype of breast cancer, and its mechanisms of occurrence and development remain unclear. In this study, we aim to investigate the role and molecular mechanisms of the demethylase FTO (fat mass and obesity-a
Externí odkaz:
https://doaj.org/article/133ed32891e240c29cd19b22359f8699
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to respiratory failure. Many preclinical studies have invest
Externí odkaz:
https://doaj.org/article/c73d06e5f9d246c99ad570c9878253a0
Autor:
Qian Wei, Jianlong Su, Sheng Meng, Yaxi Wang, Kui Ma, Bingmin Li, Ziqiang Chu, Qilin Huang, Wenzhi Hu, Zihao Wang, Lige Tian, Xi Liu, Tanshi Li, Xiaobing Fu, Cuiping Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Delayed wound healing is a major complication of diabetes, and is associated with impaired cellular functions. Current treatments are unsatisfactory. Based on the previous reports on microRNA expression in small extracellular vesicles (sEVs)
Externí odkaz:
https://doaj.org/article/ecd7ceddb3b646569c32e74fb22c5c71
Autor:
Qunwen Pan, Xiaobing Xu, Wen He, Yan Wang, Zhi Xiang, Xiaojuan Jin, Qiong Tang, Ting Zhao, Xiaotang Ma
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-17 (2023)
Abstract Background/aims Diabetes mellitus (DM) is highly susceptible to diabetic hind limb ischemia (DHI). MicroRNA (MiR)-17-5p is downregulated in DM and plays a key role in vascular protection. Endothelial progenitor cell (EPC)-released exosomes (
Externí odkaz:
https://doaj.org/article/119e86862bb44bc9acfd3c8c2a281b06
Autor:
Nazila Bostanshirin, Bahareh Hajikhani, Amir Abbas Vaezi, Fatemeh Kermanian, Fatemeh Sameni, Somayeh Yaslianifard, Mehdi Goudarzi, Masoud Dadashi
Publikováno v:
Infectious Agents and Cancer, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract Background Colorectal cancer (CRC) is considered the second-deadliest and third-most common malignancy worldwide. Studying the carcinogenic mechanism of bacteria or their role in aggravating cancer can be precious. Fusobacterium nucleatum (F
Externí odkaz:
https://doaj.org/article/4d4ac3dcfe3842728e6fbd35e1979619