Zobrazeno 1 - 10
of 537
pro vyhledávání: '"miR‐146a‐5p"'
Autor:
Wittaya Chaiwangyen, Orawan Khantamat, Komsak Pintha, Napapan Kangwan, Amnart Onsa-ard, Piyawan Nuntaboon, Angkana Songkrao, Pilaiporn Thippraphan, Dana Chaiyasit, Francisco Lázaro Pereira de Sousa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Air pollution poses a significant global concern, notably impacting pregnancy outcomes through mechanisms such as DNA damage, oxidative stress, inflammation, and altered miRNA expression, all of which can adversely affect trophoblast functio
Externí odkaz:
https://doaj.org/article/23050718864b498a8c1da25a1a208303
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAllergic asthma is prevalent in children, with Dermatophagoides farinae as a common indoor allergen. Current treatments for allergic airway inflammation are limited and carry risks. Mesenchymal stem cell-derived extracellular vesicles (MS
Externí odkaz:
https://doaj.org/article/103abe7461214ebe9a7873963c907dd8
Autor:
Chunyu Zhao, Jianing Li
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Hypoxia/reoxygenation (H/R) induces cardiomyocyte ferroptosis, a core remodeling event in myocardial ischemia/reperfusion injury. Methyltransferase-like 14 (METTL14) emerges as a writer of N6-methyladenosine (m6A) modification. Th
Externí odkaz:
https://doaj.org/article/c414905c708c4a10bce1a68dcd8586e5
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Aim To elaborate the underlying mechanisms by which IL-1β promote progression of Dry eye disease(DED) through effect on pyroptosis and apoptosis of corneal epithelial cells(CECs). Methods 400 mOsM solutions were used to establish the DED mo
Externí odkaz:
https://doaj.org/article/22c7bdafd0ce4da1b989232ea227fd06
Autor:
Dongdong Lu, Yisi Liu, Luyuan Kang, Xiangyu Zhang, Jie Hu, Hao Ye, Bingxu Huang, Yujun Wu, Jinbiao Zhao, Zhaolai Dai, Junjun Wang, Dandan Han
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Backgrounds The intestinal development in early life is profoundly influenced by multiple biological components of breast milk, in which milk-derived extracellular vesicles (mEVs) contain a large amount of vertically transmitted signal from
Externí odkaz:
https://doaj.org/article/6c6e85fcb0da4aa4929245e390c9e96a
Autor:
Fengting Zhu, Taotan Yang, Mengmeng Ning, Yang Liu, Wei Xia, Yan Fu, Ting Wen, Mei Zheng, Ruilong Xia, Ran Qian, Yang Li, Minxuan Sun, Jianping Liu, Li Tian, Qian Zhou, Xin Yu, Changgeng Peng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionInflammatory bowel disease (IBD) is a chronic disease involving multiple genes, and the current available targeted drugs for IBD only deliver moderate efficacy. Whether there is a single gene that systematically regulates IBD is not yet k
Externí odkaz:
https://doaj.org/article/c5d3fffd77b24617a10f5bd96229db22
Publikováno v:
Thoracic Cancer, Vol 15, Iss 1, Pp 44-56 (2024)
Abstract Background Circular RNAs (circRNAs) have been reported to be involved in the initiation and development of cancers. The aim of this study was to determine the role of a circRNA, circ_0020123, in the development of non‐small cell lung cance
Externí odkaz:
https://doaj.org/article/8adbc19eff8e43a2b79ca5b344b5fff7
Autor:
Qingfeng Lv, Yuan Wang, Wei Tian, Yuqiu Liu, Mengqi Gu, Xiaotong Jiang, Yanjun Cai, Ruiheng Huo, Yuchen Li, Lei Li, Xietong Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Exosomes originating from human umbilical cord mesenchymal stem cells (hucMSC-exos) have become a novel strategy for treating various diseases owing to their ability to regulate intercellular signal communication. However, the potential of h
Externí odkaz:
https://doaj.org/article/0fa33ef19c18429daafafa8aed48b648
miR-146a-5p inhibits proliferation and invasion of prostate cancer cell line PC-3 by targeting SMAD4
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 8, Pp 1215-1221 (2023)
Objective To explore the inhibition effect and mechanism of miR-146a-5p on proliferation and invasion of prostate cancer (PCa) cell line PC-3 by targeting SMAD4. Methods RT-qPCR was used to detect the expression of miR-146a-5p in PCa tissues and cell
Externí odkaz:
https://doaj.org/article/00d8f2d0088b4f53a4cc8204fe379b7f
Autor:
Klodjan Stafa, Antonella Rella, Whitby Eagle, Kelly Dong, Kelsey Morris, Dawn Layman, Krystle Corallo, Jacqueline Trivero, Robert Maidhof, Earl Goyarts, Nadine Pernodet
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction: The skin is the largest organ of the human body and fulfills protective, immune, and metabolic functions. Skin function and barrier integrity are actively regulated through circadian rhythm–associated genes and epigenetic mechanisms i
Externí odkaz:
https://doaj.org/article/38e549ebc7f940cc8159b316bea52a90